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F1LNK2 (F1LNK2_RAT) Unreviewed, UniProtKB/TrEMBL

Last modified April 3, 2013. Version 19. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesSubmitted name:
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 Ensembl ENSRNOP00000048553
Gene names
Name:Plcb4 Ensembl ENSRNOP00000048553 RGD 3345
OrganismRattus norvegicus (Rat) [Reference proteome] Ensembl ENSRNOP00000048553
Taxonomic identifier10116 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Rattus

Protein attributes

Sequence length1176 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Sequence similarities

Contains 1 C2 domain. RuleBase RU003412 SAAS SAAS008973

Contains 1 PI-PLC X-box domain. SAAS SAAS008973

Contains 1 PI-PLC Y-box domain. SAAS SAAS008973

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSRNOP00000048553

Sequences

Sequence LengthMass (Da)Tools
F1LNK2 [UniParc].

Last modified May 3, 2011. Version 1.
Checksum: 7D0DD3A07780A211

FASTA1,176134,570
        10         20         30         40         50         60 
MAKPYEFNWQ KEVPSFLQEG AVFDRYEEES FVFEPNCLFK VDEFGFFLTW KSEGKEGQVL 

        70         80         90        100        110        120 
ECSLINSIRL AAIPKDPKIL AALESVGKSE NDLEGRILCV CSGTDLVNIG FTYMVAENPE 

       130        140        150        160        170        180 
ITKQWVEGLR SIIHNFRANN VSPMTCLKKH WMKLAFLTNT SGKIPVRSIT RTFASGKTEK 

       190        200        210        220        230        240 
VIFQALKELG LPSGKNDEIE PAAFTYEKFY ELTQKICPRT DIEDLFKKIN GDKTDYLTVD 

       250        260        270        280        290        300 
QLVSFLNEHQ RDPRLNEILF PFYDAKRAMQ IIEMYEPDEE LKKKGLISSD GFCRYLMSDE 

       310        320        330        340        350        360 
NAPVFLDRLE LYQEMDHPLA HYFISSSHNT YLTGRQFGGK SSVEMYRQVL LAGCRCVELD 

       370        380        390        400        410        420 
CWDGKGEDQE PIITHGKAMC TDILFKDVIQ AIKETAFVTS EYPVILSFEN HCSKYQQYKM 

       430        440        450        460        470        480 
SKYCEDLFGD LLLKQALESH PLEPGRPLPS PNDLKRKILI KNKRLKPEVE KKQLEALKSM 

       490        500        510        520        530        540 
MEAGESAAPA SILEDDNEEE IESAADQEEE AHPEYKFGNE LSADDFSHKE AVANSVKKGL 

       550        560        570        580        590        600 
VTVEDEQAWM ASYKYVGATT NIHPYLSTMI NYAQPVKFQG FHVAEERNIH YNMSSFNESV 

       610        620        630        640        650        660 
GLGYLKTHAI EFVNYNKRQM SRIYPKGGRV DSSNYMPQIF WNAGCQMVSL NYQTPDLAMQ 

       670        680        690        700        710        720 
LNQGKFEYNG SCGYLLKPDF MRRPDRTFDP FSETPVDGVI AATCSVQVIS GQFLSDKKIG 

       730        740        750        760        770        780 
TYVEVDMYGL PTDTIRKEFR TRMVMNNGLN PVYNEESFVF RKVILPDLAV LRIAVYDDNN 

       790        800        810        820        830        840 
KLIGQRILPL DGLQAGYRHI SLRNEGNKPL SLPTIFCNIV LKTYVPDGFG DIVDALSDPK 

       850        860        870        880        890        900 
KFLSITEKRA DQMRAMGIET SDIADVPSDT SKNDKKGKAN PAKANVTPQS SSELRPTTTA 

       910        920        930        940        950        960 
ALGSGQEAKK GIELIPQVRI EDLKQMKAYL KHLKKQQKEL NSLKKKHAKE HSTMQKLHCT 

       970        980        990       1000       1010       1020 
QVDKIVAQYD KEKSTHEKIL EKAMKKKGGS NCLEIKKETE IKIQTLTSDH KSKVKEIVAQ 

      1030       1040       1050       1060       1070       1080 
HTKEWSEMIN THSAEEQEIR DLHLSQQCEL LRKLLINAHE QQTQQLKLSH DRESKEMRAH 

      1090       1100       1110       1120       1130       1140 
QAKISMENSK AISQDKSIKN KAERERRVRE LNSSNTKKFL EERKRLAMKQ SKEMDQLKKV 

      1150       1160       1170 
QLEHLEFLEK QNEQAKEMQQ MVKLEAEMDR RPATVV

« Hide

References

« Hide 'large scale' references
[1]"Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
Rat Genome Sequencing Project Consortium
Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J., Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G., Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G., Morgan M. expand/collapse author list , Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S., Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J., Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M., Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S., Collins F.S.
Nature 428:493-521(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Brown Norway Ensembl ENSRNOP00000048553.
[2]Ensembl
Submitted (JUL-2011) to UniProtKB
Cited for: IDENTIFICATION.
Strain: Brown Norway Ensembl ENSRNOP00000048553.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AABR06026347 Genomic DNA. No translation available.
AABR06026348 Genomic DNA. No translation available.
AABR06026349 Genomic DNA. No translation available.
IPIIPI00211614.

3D structure databases

ProteinModelPortalF1LNK2.
ModBaseSearch...

Proteomic databases

PRIDEF1LNK2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSRNOT00000042853; ENSRNOP00000048553; ENSRNOG00000033119.

Organism-specific databases

RGD3345. Plcb4.

Phylogenomic databases

GeneTreeENSGT00700000104181.

Gene expression databases

ArrayExpressF1LNK2.

Family and domain databases

Gene3D1.10.238.10. 1 hit.
2.30.29.30. 1 hit.
3.20.20.190. 2 hits.
InterProIPR000008. C2_Ca-dep.
IPR008973. C2_Ca/lipid-bd_dom_CaLB.
IPR018029. C2_membr_targeting.
IPR011992. EF-hand-like_dom.
IPR011993. PH_like_dom.
IPR001192. Pinositol_PLipase_C.
IPR016280. PLC-beta.
IPR009535. PLC-beta_CS.
IPR017946. PLC-like_Pdiesterase_TIM-brl.
IPR015359. PLipase_C_EF-hand-like.
IPR000909. PLipase_C_PInositol-sp_X_dom.
IPR001711. PLipase_C_Pinositol-sp_Y.
[Graphical view]
PANTHERPTHR10336. PTHR10336. 1 hit.
PfamPF00168. C2. 1 hit.
PF06631. DUF1154. 1 hit.
PF09279. efhand_like. 1 hit.
PF00388. PI-PLC-X. 1 hit.
PF00387. PI-PLC-Y. 1 hit.
[Graphical view]
PIRSFPIRSF000956. PLC-beta. 1 hit.
PRINTSPR00390. PHPHLIPASEC.
SMARTSM00239. C2. 1 hit.
SM00148. PLCXc. 1 hit.
SM00149. PLCYc. 1 hit.
[Graphical view]
SUPFAMSSF49562. C2_CaLB. 1 hit.
SSF51695. PLC-like_Pdiesterase_TIM-brl. 1 hit.
PROSITEPS50004. C2. 1 hit.
PS50007. PIPLC_X_DOMAIN. 1 hit.
PS50008. PIPLC_Y_DOMAIN. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio35575833.

Entry information

Entry nameF1LNK2_RAT
AccessionPrimary (citable) accession number: F1LNK2
Entry history
Integrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: May 3, 2011
Last modified: April 3, 2013
This is version 19 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info