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Protein
Submitted name:

Kallikrein 1-related peptidase C12

Gene

Klk1c12

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase, Protease, Serine proteaseUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Kallikrein 1-related peptidase C12Imported
Gene namesi
Name:Klk1c12Imported
Synonyms:LOC687880Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 1

Organism-specific databases

RGDi1303192. Klk1c12.
1596223. LOC687880.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 17Sequence analysisAdd BLAST17
ChainiPRO_500326698818 – 259Sequence analysisAdd BLAST242

Keywords - PTMi

Disulfide bondSAAS annotation

Proteomic databases

PaxDbiF1LNH4.

Expressioni

Gene expression databases

BgeeiENSRNOG00000047662.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000025631.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini25 – 256Peptidase S1InterPro annotationAdd BLAST232

Sequence similaritiesi

Belongs to the peptidase S1 family.SAAS annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG3627. Eukaryota.
COG5640. LUCA.
GeneTreeiENSGT00760000118862.
KOiK01325.
OMAiLPNENCT.
OrthoDBiEOG091G0DF7.
TreeFamiTF331065.

Family and domain databases

CDDicd00190. Tryp_SPc. 1 hit.
InterProiView protein in InterPro
IPR009003. Peptidase_S1_PA.
IPR001314. Peptidase_S1A.
IPR001254. Trypsin_dom.
IPR018114. TRYPSIN_HIS.
IPR033116. TRYPSIN_SER.
PfamiView protein in Pfam
PF00089. Trypsin. 1 hit.
PRINTSiPR00722. CHYMOTRYPSIN.
SMARTiView protein in SMART
SM00020. Tryp_SPc. 1 hit.
SUPFAMiSSF50494. SSF50494. 1 hit.
PROSITEiView protein in PROSITE
PS50240. TRYPSIN_DOM. 1 hit.
PS00134. TRYPSIN_HIS. 1 hit.
PS00135. TRYPSIN_SER. 1 hit.

Sequencei

Sequence statusi: Complete.

F1LNH4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MWLQILFLFL SVGRIDAAPP GQSRVVGGYK CEKNSQPWQV AVINRYLCGG
60 70 80 90 100
VLIDPSWVIT AAHCYSHNYH VLLGRNNLFK DEPFAQYRFV NQSFPHPDYN
110 120 130 140 150
PFFMKNHTLF PGDDHSNDLM LLHLSEPADI TDGVKVIDLP TEEPKVGSTC
160 170 180 190 200
LASGWSSTKP LEWEFPDDLQ CVNINILSNE KCIKAHTQMV TDVMLCAGEL
210 220 230 240 250
EGGKDTCNGD SGGPLLCDGV LQGITSWSSV PCGETNRPAI YTKLIKFTSW

IKEVMKENS
Length:259
Mass (Da):28,855
Last modified:May 3, 2011 - v1
Checksum:i4F37350CA6B64E1F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07003222 Genomic DNA. No translation available.
RefSeqiNP_001005382.2. NM_001005382.2.
XP_017446169.1. XM_017590680.1.

Genome annotation databases

EnsembliENSRNOT00000025631; ENSRNOP00000025631; ENSRNOG00000047662.
GeneIDi292855.
687880.
KEGGirno:292855.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07003222 Genomic DNA. No translation available.
RefSeqiNP_001005382.2. NM_001005382.2.
XP_017446169.1. XM_017590680.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000025631.

Proteomic databases

PaxDbiF1LNH4.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000025631; ENSRNOP00000025631; ENSRNOG00000047662.
GeneIDi292855.
687880.
KEGGirno:292855.

Organism-specific databases

CTDi292855.
RGDi1303192. Klk1c12.
1596223. LOC687880.

Phylogenomic databases

eggNOGiKOG3627. Eukaryota.
COG5640. LUCA.
GeneTreeiENSGT00760000118862.
KOiK01325.
OMAiLPNENCT.
OrthoDBiEOG091G0DF7.
TreeFamiTF331065.

Gene expression databases

BgeeiENSRNOG00000047662.

Family and domain databases

CDDicd00190. Tryp_SPc. 1 hit.
InterProiView protein in InterPro
IPR009003. Peptidase_S1_PA.
IPR001314. Peptidase_S1A.
IPR001254. Trypsin_dom.
IPR018114. TRYPSIN_HIS.
IPR033116. TRYPSIN_SER.
PfamiView protein in Pfam
PF00089. Trypsin. 1 hit.
PRINTSiPR00722. CHYMOTRYPSIN.
SMARTiView protein in SMART
SM00020. Tryp_SPc. 1 hit.
SUPFAMiSSF50494. SSF50494. 1 hit.
PROSITEiView protein in PROSITE
PS50240. TRYPSIN_DOM. 1 hit.
PS00134. TRYPSIN_HIS. 1 hit.
PS00135. TRYPSIN_SER. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiF1LNH4_RAT
AccessioniPrimary (citable) accession number: F1LNH4
Entry historyiIntegrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: May 3, 2011
Last modified: April 12, 2017
This is version 47 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.