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Protein
Submitted name:

Aldehyde dehydrogenase, mitochondrial

Gene

Aldh2

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionOxidoreductaseUniRule annotation

Enzyme and pathway databases

ReactomeiR-RNO-380612. Metabolism of serotonin.
R-RNO-71384. Ethanol oxidation.

Names & Taxonomyi

Protein namesi
Submitted name:
Aldehyde dehydrogenase, mitochondrialImported
Submitted name:
RCG21519, isoform CRA_aImported
Gene namesi
Name:Aldh2Imported
ORF Names:rCG_21519Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 12

Organism-specific databases

RGDi69219. Aldh2.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSRNOG00000001344.

Structurei

3D structure databases

SMRiF1LN88.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini47 – 510AldedhInterPro annotationAdd BLAST464

Sequence similaritiesi

Belongs to the aldehyde dehydrogenase family.UniRule annotation

Phylogenomic databases

eggNOGiKOG2450. Eukaryota.
COG1012. LUCA.
GeneTreeiENSGT00760000118999.
OMAiTFVQEDV.
OrthoDBiEOG091G05E8.
TreeFamiTF300455.

Family and domain databases

Gene3Di3.40.605.10. 1 hit.
InterProiView protein in InterPro
IPR016161. Ald_DH/histidinol_DH.
IPR016160. Ald_DH_CS_CYS.
IPR029510. Ald_DH_CS_GLU.
IPR016162. Ald_DH_N.
IPR015590. Aldehyde_DH_dom.
PfamiView protein in Pfam
PF00171. Aldedh. 1 hit.
SUPFAMiSSF53720. SSF53720. 1 hit.
PROSITEiView protein in PROSITE
PS00070. ALDEHYDE_DEHYDR_CYS. 1 hit.
PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.

Sequencei

Sequence statusi: Complete.

F1LN88-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLRAALSTAR RGPRLSRLLS AAATSAVPAP NQQPEVFCNQ IFINNEWHDA
60 70 80 90 100
VSKKTFPTVN PSTGEVICQV AEGNKEDVDK AVKAARAAFQ LGSPWRRMDA
110 120 130 140 150
SDRGRLLYRL ADLIERDRTY LAALETLDNG KPYVISYLVD LDMVLKCLRY
160 170 180 190 200
YAGWADKYHG KTIPIDGDFF SYTRHEPVGV CGQIIPWNFP LLMQAWKLGP
210 220 230 240 250
ALATGNVVVM KVAEQTPLTA LYVANLIKEA GFPPGVVNIV PGFGPTAGAA
260 270 280 290 300
IASHEDVDKV AFTGSTEVGH LIQVAAGSSN LKRVTLELGG KSPNIIMSDA
310 320 330 340 350
DMDWAVEQAH FALFFNQGQC CCAGSRTFVQ EDVYDEFVER SVARAKSRVV
360 370 380 390 400
GNPFDSRTEQ GPQVDETQFK KILGYIKSGQ QEGAKLLCGG GAAADRGYFI
410 420 430 440 450
QPTVFGDVKD GMTIAKEEIF GPVMQILKFK TIEEVVGRAN NSKYGLAAAV
460 470 480 490 500
FTKDLDKANY LSQALQAGTV WINCYDVFGA QSPFGGYKMS GSGRELGEYG
510
LQAYTEVKTV TVKVPQKNS
Length:519
Mass (Da):56,516
Last modified:April 3, 2013 - v2
Checksum:i2B17D04DCEF302CA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07036373 Genomic DNA. No translation available.
AABR07036374 Genomic DNA. No translation available.
CH473973 Genomic DNA. Translation: EDM13724.1.
CH473973 Genomic DNA. Translation: EDM13725.1.
CH473973 Genomic DNA. Translation: EDM13726.1.
RefSeqiXP_006249447.1. XM_006249385.3.
UniGeneiRn.101781.

Genome annotation databases

EnsembliENSRNOT00000001816; ENSRNOP00000001816; ENSRNOG00000001344.
GeneIDi29539.

Similar proteinsi

Entry informationi

Entry nameiF1LN88_RAT
AccessioniPrimary (citable) accession number: F1LN88
Entry historyiIntegrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: April 3, 2013
Last modified: December 20, 2017
This is version 55 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported