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Protein
Submitted name:

Disabled homolog 2

Gene

Dab2

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-RNO-190873 Gap junction degradation
R-RNO-196025 Formation of annular gap junctions
R-RNO-8856825 Cargo recognition for clathrin-mediated endocytosis
R-RNO-8856828 Clathrin-mediated endocytosis

Names & Taxonomyi

Protein namesi
Submitted name:
Disabled homolog 2Imported
Gene namesi
Name:Dab2Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 2

Organism-specific databases

RGDi621007 Dab2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

PeptideAtlasiF1LMP9
PRIDEiF1LMP9

Expressioni

Gene expression databases

BgeeiENSRNOG00000028930

Interactioni

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini45 – 196PIDInterPro annotationAdd BLAST152

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili171 – 192Sequence analysisAdd BLAST22

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG3535 Eukaryota
ENOG410XZ1H LUCA
GeneTreeiENSGT00520000055585
OMAiIPQENAD
OrthoDBiEOG091G0382
TreeFamiTF316724

Family and domain databases

Gene3Di2.30.29.30, 1 hit
InterProiView protein in InterPro
IPR011993 PH-like_dom_sf
IPR006020 PTB/PI_dom
PfamiView protein in Pfam
PF00640 PID, 1 hit
SMARTiView protein in SMART
SM00462 PTB, 1 hit
PROSITEiView protein in PROSITE
PS01179 PID, 1 hit

Sequencei

Sequence statusi: Complete.

F1LMP9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSNEVETSTT NGQPDQQAAP KAPSKKEKKK GSEKTDEYLL ARFKGDGVKY
60 70 80 90 100
KAKLIGIDDV PDARGDKMSQ DSMMKLKGMA AAGRSQGQHK QRIWVNISLS
110 120 130 140 150
GIKIIDEKTG VIEHEHPVNK ISFIARDVTD NRAFGYVCGG EGQHQFFAIK
160 170 180 190 200
TGQQAEPLVV DLKDLFQVIY NVKKKEEEKK KVEEANKAEE NGSEALMTLD
210 220 230 240 250
DQANKLKLGV DQMDLFGDMS TPPDLNNPTE SRDILLVDLN SEIDTNQNSL
260 270 280 290 300
RENPFLTNGV TSCSLPRPKP QASFLPESAF SANLNFFPTP NPDPFRDDPF
310 320 330 340 350
AQPDQSAPSS FHSLTSADQK KANPGSLSTP QSKRPLNGDT DYFGQQFDQI
360 370 380 390 400
SNRTGKQEAQ GGPWPYPSSQ TQQAVRTQNG VSEQNGFHIK SSPNPFVGSP
410 420 430 440 450
PKGLSVPNGV KQDLESSVQS SAHDSIAIIP PPQSTKPGRG RRTAKSSAND
460 470 480 490 500
LLASDIFASE PPGQMSPTGQ PAVPQANFMD LFKTSAPAPM GSGPLVGLGT
510 520 530 540 550
VPVTPPQAGP WTPVVFTPST TVVPGAIISG QPSGFGQPLV FGTTPAVQVW
560 570 580 590 600
NQPSSFATAA SPPPPAVWCP TTSVAPNTWS STSPLGNPFQ SSNIFPPSTI
610 620 630 640 650
STQSFPQPMM SSVLVTPPQP PPRNGPLKDT LSDAFTGLDP LGDKEVKEVK
660 670 680 690 700
EMFKDFQLRQ PPLVPSRKGE TPSSGTSSAF SSYFNNKVGI PQEHVDHDDF
710 720 730 740 750
DANQLLNKIN EPPKPAPRQG VLSGTKSADN SLENPFSKGF SSTNPSVVSQ
760
PASSDAHRSP FGNPFA
Length:766
Mass (Da):82,219
Last modified:July 22, 2015 - v3
Checksum:iD5B12B2EABC3409E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07008397 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSRNOT00000050655; ENSRNOP00000043878; ENSRNOG00000028930

Similar proteinsi

Entry informationi

Entry nameiF1LMP9_RAT
AccessioniPrimary (citable) accession number: F1LMP9
Entry historyiIntegrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: July 22, 2015
Last modified: March 28, 2018
This is version 50 of the entry and version 3 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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Main funding by: National Institutes of Health