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Protein
Submitted name:

Plasminogen activator inhibitor 1

Gene

Serpine1

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-RNO-114608. Platelet degranulation.
R-RNO-3000178. ECM proteoglycans.
R-RNO-75205. Dissolution of Fibrin Clot.

Names & Taxonomyi

Protein namesi
Submitted name:
Plasminogen activator inhibitor 1Imported
Gene namesi
Name:Serpine1Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 12

Organism-specific databases

RGDi3249. Serpine1.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 23Sequence analysisAdd BLAST23
ChainiPRO_500326597824 – 402Sequence analysisAdd BLAST379

Proteomic databases

PaxDbiF1LM16.

Expressioni

Gene expression databases

BgeeiENSRNOG00000001414.

Interactioni

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini40 – 402SERPINInterPro annotationAdd BLAST363

Sequence similaritiesi

Belongs to the serpin family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG2392. Eukaryota.
COG4826. LUCA.
GeneTreeiENSGT00900000140788.
OMAiPYEKEVP.
OrthoDBiEOG091G0ION.
TreeFamiTF352620.

Family and domain databases

InterProiView protein in InterPro
IPR023795. Serpin_CS.
IPR023796. Serpin_dom.
IPR000215. Serpin_fam.
IPR036186. Serpin_sf.
PANTHERiPTHR11461. PTHR11461. 1 hit.
PfamiView protein in Pfam
PF00079. Serpin. 1 hit.
SMARTiView protein in SMART
SM00093. SERPIN. 1 hit.
SUPFAMiSSF56574. SSF56574. 1 hit.
PROSITEiView protein in PROSITE
PS00284. SERPIN. 1 hit.

Sequencei

Sequence statusi: Complete.

F1LM16-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQMSSALTCL TLGLVLVFGK GFASPLPESH TAQQATNFGV KVFQHVVQAS
60 70 80 90 100
KDRNVVFSPY GVSSVLAMLQ LTTAGKTRQQ IQDAMGFNIS ERGTAPALRK
110 120 130 140 150
LSKELMGSWN KNEISTADAI FVQRDLELVQ GFMPHFFKLF RTTVKQVDFS
160 170 180 190 200
EMERARFIIN DWVERHTKGM ISDLLAKGAV NELTRLVLVN ALYFNGQWKT
210 220 230 240 250
PFLEASTHQR LFHKSDGSTI SVPMMAQNNK FNYTEFTTPD GHEYDILELP
260 270 280 290 300
YHGETLSMFI AAPFEKDVPL SAITNILDAE LIRQWKSNMT RLPRLLILPK
310 320 330 340 350
FSLETEVDLR GPLEKLGMTD IFSSTQADFT SLSDQEQLSV AQALQKVKIE
360 370 380 390 400
VNESGTVASS STAILVSARM APTEMVLDRS FLFVVRHNPT ETILFMGQLM

EP
Length:402
Mass (Da):45,042
Last modified:May 3, 2011 - v1
Checksum:i2B6397F7F475E403
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07035800 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSRNOT00000001916; ENSRNOP00000001916; ENSRNOG00000001414.

Similar proteinsi

Entry informationi

Entry nameiF1LM16_RAT
AccessioniPrimary (citable) accession number: F1LM16
Entry historyiIntegrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: May 3, 2011
Last modified: October 25, 2017
This is version 51 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported