ID   F1KZZ8_ASCSU            Unreviewed;       278 AA.
AC   F1KZZ8;
DT   03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT   03-MAY-2011, sequence version 1.
DT   27-MAR-2024, entry version 44.
DE   RecName: Full=Galectin {ECO:0000256|RuleBase:RU102079};
OS   Ascaris suum (Pig roundworm) (Ascaris lumbricoides).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Ascaridomorpha; Ascaridoidea; Ascarididae; Ascaris.
OX   NCBI_TaxID=6253 {ECO:0000313|EMBL:ADY43452.1};
RN   [1] {ECO:0000313|EMBL:ADY43452.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=21685128; DOI=10.1101/gr.121426.111;
RA   Wang J., Czech B., Crunk A., Wallace A., Mitreva M., Hannon G.J.,
RA   Davis R.E.;
RT   "Deep small RNA sequencing from the nematode Ascaris reveals conservation,
RT   functional diversification, and novel developmental profiles.";
RL   Genome Res. 21:1462-1477(2011).
RN   [2] {ECO:0007829|PDB:4HL0}
RP   X-RAY CRYSTALLOGRAPHY (2.00 ANGSTROMS).
RX   PubMed=23385453; DOI=10.1107/S0907444912045106;
RA   Jeong M.S., Hwang H.G., Yu H.S., Jang S.B.;
RT   "Structure of full-length Toxascaris leonina galectin with two
RT   carbohydrate-recognition domains.";
RL   Acta Crystallogr. D 69:168-175(2013).
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DR   EMBL; JI168813; ADY43452.1; -; mRNA.
DR   PDB; 4HL0; X-ray; 2.00 A; A/B=1-278.
DR   PDBsum; 4HL0; -.
DR   AlphaFoldDB; F1KZZ8; -.
DR   SMR; F1KZZ8; -.
DR   UniLectin; F1KZZ8; -.
DR   GO; GO:0030246; F:carbohydrate binding; IEA:UniProtKB-UniRule.
DR   CDD; cd00070; GLECT; 2.
DR   Gene3D; 2.60.120.200; -; 2.
DR   InterPro; IPR013320; ConA-like_dom_sf.
DR   InterPro; IPR044156; Galectin-like.
DR   InterPro; IPR001079; Galectin_CRD.
DR   PANTHER; PTHR11346; GALECTIN; 1.
DR   PANTHER; PTHR11346:SF189; GALECTIN; 1.
DR   Pfam; PF00337; Gal-bind_lectin; 2.
DR   SMART; SM00908; Gal-bind_lectin; 2.
DR   SMART; SM00276; GLECT; 2.
DR   SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 2.
DR   PROSITE; PS51304; GALECTIN; 2.
PE   1: Evidence at protein level;
KW   3D-structure {ECO:0007829|PDB:4HL0};
KW   Lectin {ECO:0000256|RuleBase:RU102079, ECO:0000313|EMBL:ADY43452.1}.
FT   DOMAIN          11..142
FT                   /note="Galectin"
FT                   /evidence="ECO:0000259|PROSITE:PS51304"
FT   DOMAIN          151..278
FT                   /note="Galectin"
FT                   /evidence="ECO:0000259|PROSITE:PS51304"
SQ   SEQUENCE   278 AA;  31422 MW;  192A0ED78667A695 CRC64;
     MATETSYPVP YRSKLTEPFE PGQTLIIKGK TAEDSVRFTI NLHNTSADFS GNDVPLHISV
     RFDEGKIVFN TFSKGEWGKE ERKSNPYKKG DDIDIRIRAH DSKFSISVDQ KEVKEYEHRV
     PLSSVTHFSV DGDILITYIH WGGKYYPVPY ESGLAGDGLA PGKSLLIFAT PEKKGKRFHI
     NLLKKNGDIA LHFNPRFDEK AIVRNSLISG EWGNEEREGK NPLEKGIGCD LEFRNEEYAF
     QIYVDGERFA TYAHRLDPHD INGLQIGGDV EVTGIQMV
//