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Protein
Submitted name:

Ligand-gated ion channel 4

Gene

ASU_09594

Organism
Ascaris suum (Pig roundworm) (Ascaris lumbricoides)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionIon channelUniRule annotation, ReceptorImported
Biological processIon transport, Transport

Names & Taxonomyi

Protein namesi
Submitted name:
Ligand-gated ion channel 4Imported
Submitted name:
Neuronal acetylcholine receptor subunit alpha-10Imported
Gene namesi
ORF Names:ASU_09594Imported
OrganismiAscaris suum (Pig roundworm) (Ascaris lumbricoides)Imported
Taxonomic identifieri6253 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaAscarididaAscaridoideaAscarididaeAscaris
Proteomesi
  • UP000017900 Componenti: Unassembled WGS sequence

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei266 – 289HelicalSequence analysisAdd BLAST24
Transmembranei301 – 319HelicalSequence analysisAdd BLAST19
Transmembranei339 – 364HelicalSequence analysisAdd BLAST26
Transmembranei500 – 518HelicalSequence analysisAdd BLAST19

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 20Sequence analysisAdd BLAST20
ChainiPRO_500765556521 – 523Sequence analysisAdd BLAST503

Structurei

3D structure databases

ProteinModelPortaliF1KX45.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini61 – 264Neur_chan_LBDInterPro annotationAdd BLAST204

Sequence similaritiesi

Belongs to the ligand-gated ion channel (TC 1.A.9) family. [View classification]UniRule annotationSAAS annotation

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Family and domain databases

Gene3Di1.20.58.390. 1 hit.
2.70.170.10. 1 hit.
InterProiView protein in InterPro
IPR006202. Neur_chan_lig-bd.
IPR036734. Neur_chan_lig-bd_sf.
IPR006201. Neur_channel.
IPR036719. Neuro-gated_channel_TM_sf.
IPR018000. Neurotransmitter_ion_chnl_CS.
PANTHERiPTHR18945. PTHR18945. 1 hit.
PfamiView protein in Pfam
PF02931. Neur_chan_LBD. 1 hit.
PRINTSiPR00252. NRIONCHANNEL.
SUPFAMiSSF63712. SSF63712. 1 hit.
SSF90112. SSF90112. 1 hit.
PROSITEiView protein in PROSITE
PS00236. NEUROTR_ION_CHANNEL. 1 hit.

Sequencei

Sequence statusi: Complete.

F1KX45-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRVFGALLLS LIKFVVPSEG FVSKSRLRSK ETEIDLKSNK GTEMDFEHDD
60 70 80 90 100
FTIIESDAHS RLIGYIRRRA RPFQRPVLHS HSPIDIHVRA ALYQIVDLDQ
110 120 130 140 150
RNNLATLSAY FDVWWIDDFV KWNASQFDGI TKTFIPARWI WKPEFYLYHS
160 170 180 190 200
VQGRIPDYAP DATAEINGDG RLRMFIPVTS RALCPINVKY FPFDTQNCTF
210 220 230 240 250
ACGSWSYQFE FVKLLVEDEA VFLGDFYDNQ EWLLENATLY NGTLGYLGNE
260 270 280 290 300
SFSTVYMELM LRRQSFYYVF NFVFPITLVS LVAIIGFHAP INATGRRESK
310 320 330 340 350
FRLGIMTLLS MSVMLLMLVD EMKFALASIP GQRGSFSDVP LLGVFHMIQI
360 370 380 390 400
LIISVATCTS SVFVHLEKYA LRNQSFHAIP WWLRFLTAEK LFCCYVPPKL
410 420 430 440 450
RRSRREEPKR NNYIVTHSVN SSPENTVERN LIPTDVNFVE CQQESAVSEM
460 470 480 490 500
VLEGPPPITT QRIELLVSLM RQFIHMKHEM QRRHSLPPYW ERVIRRLENL
510 520
SLSTYLLLIG INVTMFMYPE LWY
Length:523
Mass (Da):60,932
Last modified:May 3, 2011 - v1
Checksum:iE5528E7649A1670B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JI167353 mRNA. Translation: ADY42449.1.
AEUI02000395 Genomic DNA. Translation: ERG81817.1.

Similar proteinsi

Entry informationi

Entry nameiF1KX45_ASCSU
AccessioniPrimary (citable) accession number: F1KX45
Entry historyiIntegrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: May 3, 2011
Last modified: October 25, 2017
This is version 39 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported