F1DAL0 (F1DAL0_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Thyroid hormone nuclear receptor alpha EMBL ADZ17381.1

Gene names

Name:

NR1F1 EMBL ADZ17381.1

Organism

Homo sapiens (Human) EMBL ADZ17381.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	467 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Belongs to the nuclear hormone receptor family. RuleBase RU000377 Contains 1 nuclear receptor DNA-binding domain. SAAS SAAS000536

Ontologies

Keywords
Biological process	Transcription Transcription regulation RuleBase RU004334 SAAS SAAS000536
Cellular component	Nucleus RuleBase RU004334 SAAS SAAS000536
Domain	Zinc-finger RuleBase RU004334 SAAS SAAS000536
Ligand	DNA-binding RuleBase RU004334 SAAS SAAS000536 Metal-binding Zinc
Molecular function	Receptor RuleBase RU004334 EMBL ADZ17381.1
Gene Ontology (GO)
Biological_process	intracellular receptor mediated signaling pathway Inferred from electronic annotation. Source: GOC
Cellular_component	nucleus Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity Inferred from electronic annotation. Source: InterPro sequence-specific DNA binding Inferred from electronic annotation. Source: InterPro steroid hormone receptor activity Inferred from electronic annotation. Source: InterPro zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	F1DAL0 [UniParc]. Last modified May 3, 2011. Version 1. Checksum: 47FCD7891A149D5B	FASTA	467	53,412
	10 20 30 40 50 60 MMYFVIAAMK AQIEIIPCKI CGDKSSGIHY GVITCEGCKG FFRRSQQSNA TYSCPRQKNC 70 80 90 100 110 120 LIDRTSRNRC QHCRLQKCLA VGMSRDAVKF GRMSKKQRDS LYAEVQKHRM QQQQRDHQQQ 130 140 150 160 170 180 PGEAEPLTPT YNISANGLTE LHDDLSNYID GHTPEGSKAD SAVSSFYLDI QPSPDQSGLD 190 200 210 220 230 240 INGIKPEPIC DYTPASGFFP YCSFTNGETS PTVSMAELEH LAQNISKSHL ETCQYLREEL 250 260 270 280 290 300 QQITWQTFLQ EEIENYQNKR EVMWQLCAIK ITEAIQYVVE FAKRIDGFME LCQNDQIVLL 310 320 330 340 350 360 KAGSLEVVFI RMCRAFDSQN NTVYFDGKYA SPDVFKSLGC EDFISFVFEF GKSLCSMHLT 370 380 390 400 410 420 EDEIALFSAF VLMSADRSWL QEKVKIEKLQ QKIQLALQHV LQKNHREDGI LTKLICKVST 430 440 450 460 LRALCGRHTE KLMAFKAIYP DIVRLHFPPL YKELFTSEFE PAMQIDG

References

[1]	"Isolation of cDNA coding for putatively new variants of multiple human nuclear receptors." Kaighin V.A., Martin A.L., Aronstam R.S. Submitted (DEC-2010) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Kidney EMBL ADZ17381.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	HQ709174 mRNA. Translation: ADZ17381.1.
IPI	IPI00243584.
UniGene	Hs.560343. Hs.655155.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
UCSC	uc021sni.1. human.
Gene expression databases
ArrayExpress	F1DAL0.
Bgee	F1DAL0.
Family and domain databases
Gene3D	1.10.565.10. 2 hits. 3.30.50.10. 1 hit.
InterPro	IPR008946. Nucl_hormone_rcpt_ligand-bd. IPR000536. Nucl_hrmn_rcpt_lig-bd_core. IPR003079. ROR_rcpt. IPR001723. Str_hrmn_rcpt. IPR001628. Znf_hrmn_rcpt. IPR013088. Znf_NHR/GATA. [Graphical view]
Pfam	PF00104. Hormone_recep. 1 hit. PF00105. zf-C4. 1 hit. [Graphical view]
PRINTS	PR01293. RORNUCRECPTR. PR00398. STRDHORMONER. PR00047. STROIDFINGER.
SMART	SM00430. HOLI. 1 hit. SM00399. ZnF_C4. 1 hit. [Graphical view]
SUPFAM	SSF48508. Str_ncl_receptor. 1 hit.
PROSITE	PS00031. NUCLEAR_REC_DBD_1. 1 hit. PS51030. NUCLEAR_REC_DBD_2. 1 hit. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	RORA. human.
NextBio	35505313.

Entry information

Entry name

F1DAL0_HUMAN

Accession

Primary (citable) accession number: F1DAL0

Entry history

Integrated into UniProtKB/TrEMBL:	May 3, 2011
Last sequence update:	May 3, 2011
Last modified:	April 3, 2013
This is version 14 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.