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Protein
Submitted name:

RAR-related orphan nuclear receptor variant 2

Gene

NR1F3

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi7 – 82Nuclear receptorPROSITE-ProRule annotationAdd BLAST76

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotationSAAS annotation, ReceptorUniRule annotationImported
Biological processTranscription, Transcription regulationPROSITE-ProRule annotationSAAS annotation
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
RAR-related orphan nuclear receptor variant 2Imported
Gene namesi
Name:NR1F3Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

  • Nucleus PROSITE-ProRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

PTM / Processingi

Proteomic databases

PaxDbiF1D8P6.
PRIDEiF1D8P6.

Expressioni

Gene expression databases

BgeeiENSG00000143365.
ExpressionAtlasiF1D8P6. baseline and differential.
GenevisibleiF1D8P6. HS.

Structurei

3D structure databases

ProteinModelPortaliF1D8P6.
SMRiF1D8P6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini7 – 82Nuclear receptor DNA-bindingInterPro annotationAdd BLAST76

Sequence similaritiesi

Belongs to the nuclear hormone receptor family.UniRule annotationSAAS annotation

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG4216. Eukaryota.
ENOG410XUGR. LUCA.

Family and domain databases

Gene3Di3.30.50.10. 1 hit.
InterProiView protein in InterPro
IPR000536. Nucl_hrmn_rcpt_lig-bd.
IPR001723. Nuclear_hrmn_rcpt.
IPR003079. ROR_rcpt.
IPR001628. Znf_hrmn_rcpt.
IPR013088. Znf_NHR/GATA.
PfamiView protein in Pfam
PF00104. Hormone_recep. 1 hit.
PF00105. zf-C4. 1 hit.
PRINTSiPR01293. RORNUCRECPTR.
PR00398. STRDHORMONER.
PR00047. STROIDFINGER.
SMARTiView protein in SMART
SM00430. HOLI. 1 hit.
SM00399. ZnF_C4. 1 hit.
SUPFAMiSSF48508. SSF48508. 1 hit.
PROSITEiView protein in PROSITE
PS00031. NUCLEAR_REC_DBD_1. 1 hit.
PS51030. NUCLEAR_REC_DBD_2. 1 hit.

Sequencei

Sequence statusi: Complete.

F1D8P6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRTQIEVIPC KICGDKSSGI HYGVITCEGC KGFFRRSQRC NAAYSCTRQQ
60 70 80 90 100
NCPIDRTSRN RCQHCRLQKC LALGMSRDAV KFGRMSKKQR DSLHAEVQKQ
110 120 130 140 150
LQQRQQQQQE PVVKTPPAGA QGADTLTYTL GLPDGQLPLG SSPDLPEASA
160 170 180 190 200
CPPGLLKASG SGPSYSNNLA KAGLNGASCH LEYSPERGKA EGRESFYSTG
210 220 230 240 250
SQLTPDRCGL RFEEHRHPGL GELGQGPDSY GSPSFRSTPE APYASLTEIE
260 270 280 290 300
HLVQSVCKSY RETCQLRLED LLRQRSNIFS REEVTGYQRK SMWEMWERCA
310 320 330 340 350
HHLTEAIQYV VEFAKRLSGF MELCQNDQIV LLKAGAMEVV LVRMCRAYNA
360 370 380 390 400
DNRTVFFEGK YGGMELFRAL GCSELISSIF DFSHSLSALH FSEDEIALYT
410 420 430 440 450
ALVLINAHRP GLQEKRKVEQ LQYNLELAFH HHLCKTHRQS ILAKLPPKGK
460 470 480 490
LRSLCSQHVE RLQIFQHLHP IVVQAAFPPL YKELFSTETE SPVGLSK
Length:497
Mass (Da):55,813
Last modified:May 3, 2011 - v1
Checksum:i6D0048673483EA11
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HQ692834 mRNA. Translation: ADZ17345.1.
RefSeqiNP_001001523.1. NM_001001523.1.
UniGeneiHs.256022.
Hs.607993.

Genome annotation databases

GeneIDi6097.

Similar proteinsi

Entry informationi

Entry nameiF1D8P6_HUMAN
AccessioniPrimary (citable) accession number: F1D8P6
Entry historyiIntegrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: May 3, 2011
Last modified: July 5, 2017
This is version 52 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.