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Protein
Submitted name:

Retinoic acid nuclear receptor gamma variant 2

Gene

NR1B3

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi76 – 151Nuclear receptorPROSITE-ProRule annotationAdd BLAST76

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotationSAAS annotation, ReceptorUniRule annotationImported
Biological processTranscription, Transcription regulationPROSITE-ProRule annotationSAAS annotation
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Retinoic acid nuclear receptor gamma variant 2Imported
Gene namesi
Name:NR1B3Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

  • Nucleus PROSITE-ProRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

PTM / Processingi

Proteomic databases

PRIDEiF1D8P1.

Expressioni

Gene expression databases

BgeeiENSG00000172819.
ExpressionAtlasiF1D8P1. baseline and differential.
GenevisibleiF1D8P1. HS.

Structurei

3D structure databases

ProteinModelPortaliF1D8P1.
SMRiF1D8P1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini76 – 151Nuclear receptor DNA-bindingInterPro annotationAdd BLAST76

Sequence similaritiesi

Belongs to the nuclear hormone receptor family.UniRule annotationSAAS annotation

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Family and domain databases

Gene3Di1.10.565.10. 1 hit.
3.30.50.10. 1 hit.
InterProiView protein in InterPro
IPR000536. Nucl_hrmn_rcpt_lig-bd.
IPR001723. Nuclear_hrmn_rcpt.
IPR003078. Retinoic_acid_rcpt.
IPR001628. Znf_hrmn_rcpt.
IPR013088. Znf_NHR/GATA.
PfamiView protein in Pfam
PF00104. Hormone_recep. 1 hit.
PF00105. zf-C4. 1 hit.
PRINTSiPR01292. RETNOICACIDR.
PR00398. STRDHORMONER.
PR00047. STROIDFINGER.
SMARTiView protein in SMART
SM00430. HOLI. 1 hit.
SM00399. ZnF_C4. 1 hit.
SUPFAMiSSF48508. SSF48508. 1 hit.
PROSITEiView protein in PROSITE
PS00031. NUCLEAR_REC_DBD_1. 1 hit.
PS51030. NUCLEAR_REC_DBD_2. 1 hit.

Sequencei

Sequence statusi: Complete.

F1D8P1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYDCMETFAP GPRRLYGAAG PGAGLLRRAT GGSCFAGLES FAWPQPASLQ
60 70 80 90 100
SVETQSTSSE EMVPSSPSPP PPPRVYKPCF VCNDKSSGYH YGVSSCEGCK
110 120 130 140 150
GFFRRSIQKN MVYTCHRDKN CIINKVTRNR CQYCRLQKCF EVGMSKEAVR
160 170 180 190 200
NDRNKKKKEV KEEGSPDSYE LSPQLEELIT KVSKAHQETF PSLCQLGKYT
210 220 230 240 250
TNSSADHRVQ LDLGLWDKFS ELATKCIIKI VEFAKRLPGF TGLSIADQIT
260 270 280 290 300
LLKAACLDIL MLRICTRYTP EQDTMTFSDG LTLNRTQMHN AGFGPLTDLV
310 320 330 340 350
FAFAGQLLPL EMDDTETGLL SAICLICGDR MDLEEPEKVD KLQEPLLEAL
360 370 380 390 400
RLYARRRRPS QPYMFPRMLM KITDLRGIST KGAERAITLK MEIPGPMPPL
410 420 430 440
IREMLENPEM FEDDSSQPGP HPNASSEDEV PGGQGKGGLK SPA
Length:443
Mass (Da):49,308
Last modified:May 3, 2011 - v1
Checksum:i4D709194F5111E86
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HQ692829 mRNA. Translation: ADZ17340.1.
RefSeqiNP_001036193.1. NM_001042728.2.
UniGeneiHs.1497.
Hs.733399.

Genome annotation databases

GeneIDi5916.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HQ692829 mRNA. Translation: ADZ17340.1.
RefSeqiNP_001036193.1. NM_001042728.2.
UniGeneiHs.1497.
Hs.733399.

3D structure databases

ProteinModelPortaliF1D8P1.
SMRiF1D8P1.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiF1D8P1.

Protocols and materials databases

DNASUi5916.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi5916.

Organism-specific databases

CTDi5916.

Miscellaneous databases

ChiTaRSiRARG. human.
GenomeRNAii5916.

Gene expression databases

BgeeiENSG00000172819.
ExpressionAtlasiF1D8P1. baseline and differential.
GenevisibleiF1D8P1. HS.

Family and domain databases

Gene3Di1.10.565.10. 1 hit.
3.30.50.10. 1 hit.
InterProiView protein in InterPro
IPR000536. Nucl_hrmn_rcpt_lig-bd.
IPR001723. Nuclear_hrmn_rcpt.
IPR003078. Retinoic_acid_rcpt.
IPR001628. Znf_hrmn_rcpt.
IPR013088. Znf_NHR/GATA.
PfamiView protein in Pfam
PF00104. Hormone_recep. 1 hit.
PF00105. zf-C4. 1 hit.
PRINTSiPR01292. RETNOICACIDR.
PR00398. STRDHORMONER.
PR00047. STROIDFINGER.
SMARTiView protein in SMART
SM00430. HOLI. 1 hit.
SM00399. ZnF_C4. 1 hit.
SUPFAMiSSF48508. SSF48508. 1 hit.
PROSITEiView protein in PROSITE
PS00031. NUCLEAR_REC_DBD_1. 1 hit.
PS51030. NUCLEAR_REC_DBD_2. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiF1D8P1_HUMAN
AccessioniPrimary (citable) accession number: F1D8P1
Entry historyiIntegrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: May 3, 2011
Last modified: February 15, 2017
This is version 48 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.