SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

F1D8N5

- F1D8N5_HUMAN

UniProt

F1D8N5 - F1D8N5_HUMAN

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Submitted name:

Androgen nuclear receptor variant 2

Gene
NR3C4
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. sequence-specific DNA binding Source: InterPro
  2. sequence-specific DNA binding transcription factor activity Source: InterPro
  3. steroid hormone receptor activity Source: InterPro
  4. zinc ion binding Source: InterPro

GO - Biological processi

  1. transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

ReceptorUniRule annotationImported

Keywords - Biological processi

Transcription, Transcription regulationUniRule annotationSAAS annotations

Keywords - Ligandi

DNA-bindingUniRule annotationSAAS annotations, Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Androgen nuclear receptor variant 2Imported
Gene namesi
Name:NR3C4Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. nucleus Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

NucleusUniRule annotationSAAS annotations

PTM / Processingi

Proteomic databases

PRIDEiF1D8N5.

Expressioni

Gene expression databases

ArrayExpressiF1D8N5.
BgeeiF1D8N5.

Structurei

3D structure databases

ProteinModelPortaliF1D8N5.
SMRiF1D8N5. Positions 24-97, 138-387.

Family & Domainsi

Sequence similaritiesi

Belongs to the nuclear hormone receptor family.UniRule annotation
Contains nuclear receptor DNA-binding domain.SAAS annotations

Keywords - Domaini

Zinc-fingerUniRule annotationSAAS annotations

Phylogenomic databases

KOiK08557.

Family and domain databases

Gene3Di1.10.565.10. 1 hit.
3.30.50.10. 1 hit.
InterProiIPR008946. Nucl_hormone_rcpt_ligand-bd.
IPR000536. Nucl_hrmn_rcpt_lig-bd_core.
IPR001723. Str_hrmn_rcpt.
IPR001628. Znf_hrmn_rcpt.
IPR013088. Znf_NHR/GATA.
[Graphical view]
PfamiPF00104. Hormone_recep. 1 hit.
PF00105. zf-C4. 1 hit.
[Graphical view]
PRINTSiPR00398. STRDHORMONER.
PR00047. STROIDFINGER.
SMARTiSM00430. HOLI. 1 hit.
SM00399. ZnF_C4. 1 hit.
[Graphical view]
SUPFAMiSSF48508. SSF48508. 1 hit.
PROSITEiPS00031. NUCLEAR_REC_DBD_1. 1 hit.
PS51030. NUCLEAR_REC_DBD_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F1D8N5-1 [UniParc]FASTAAdd to Basket

« Hide

MILWLHSLET ARDHVLPIDY YFPPQKTCLI CGDEASGCHY GALTCGSCKV    50
FFKRAAEGKQ KYLCASRNDC TIDKFRRKNC PSCRLRKCYE AGMTLGARKL 100
KKLGNLKLQE EGEASSTTSP TEETTQKLTV SHIEGYECQP IFLNVLEAIE 150
PGVVCAGHDN NQPDSFAALL SSLNELGERQ LVHVVKWAKA LPGFRNLHVD 200
DQMAVIQYSW MGLMVFAMGW RSFTNVNSRM LYFAPDLVFN EYRMHKSRMY 250
SQCVRMRHLS QEFGWLQITP QEFLCMKALL LFSIIPVDGL KNQKFFDELR 300
MNYIKELDRI IACKRKNPTS CSRRFYQLTK LLDSVQPIAR ELHQFTFDLL 350
IKSHMVSVDF PEMMAEIISV QVPKILSGKV KPIYFHTQ 388
Length:388
Mass (Da):44,643
Last modified:May 3, 2011 - v1
Checksum:i495BAE974B4EFC75
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
HQ692823 mRNA. Translation: ADZ17334.1.
RefSeqiNP_001011645.1. NM_001011645.2.
UniGeneiHs.76704.

Genome annotation databases

GeneIDi367.
KEGGihsa:367.
UCSCiuc004dwv.2. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
HQ692823 mRNA. Translation: ADZ17334.1 .
RefSeqi NP_001011645.1. NM_001011645.2.
UniGenei Hs.76704.

3D structure databases

ProteinModelPortali F1D8N5.
SMRi F1D8N5. Positions 24-97, 138-387.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi F1D8N5.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 367.
KEGGi hsa:367.
UCSCi uc004dwv.2. human.

Organism-specific databases

CTDi 367.

Phylogenomic databases

KOi K08557.

Miscellaneous databases

ChiTaRSi AR. human.
GenomeRNAii 367.
NextBioi 1531.

Gene expression databases

ArrayExpressi F1D8N5.
Bgeei F1D8N5.

Family and domain databases

Gene3Di 1.10.565.10. 1 hit.
3.30.50.10. 1 hit.
InterProi IPR008946. Nucl_hormone_rcpt_ligand-bd.
IPR000536. Nucl_hrmn_rcpt_lig-bd_core.
IPR001723. Str_hrmn_rcpt.
IPR001628. Znf_hrmn_rcpt.
IPR013088. Znf_NHR/GATA.
[Graphical view ]
Pfami PF00104. Hormone_recep. 1 hit.
PF00105. zf-C4. 1 hit.
[Graphical view ]
PRINTSi PR00398. STRDHORMONER.
PR00047. STROIDFINGER.
SMARTi SM00430. HOLI. 1 hit.
SM00399. ZnF_C4. 1 hit.
[Graphical view ]
SUPFAMi SSF48508. SSF48508. 1 hit.
PROSITEi PS00031. NUCLEAR_REC_DBD_1. 1 hit.
PS51030. NUCLEAR_REC_DBD_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Isolation of cDNA coding for multiple human nuclear receptor clones."
    Kaighin V.A., Martin A.L., Aronstam R.S.
    Submitted (DEC-2010) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: LungImported.

Entry informationi

Entry nameiF1D8N5_HUMAN
AccessioniPrimary (citable) accession number: F1D8N5
Entry historyi
Integrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: May 3, 2011
Last modified: March 19, 2014
This is version 20 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi