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F0ZSY6

- F0ZSY6_DICPU

UniProt

F0ZSY6 - F0ZSY6_DICPU

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Protein

DNA ligase

Gene

DICPUDRAFT_81260

Organism
Dictyostelium purpureum (Slime mold)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. DNA binding Source: InterPro
  3. DNA ligase (ATP) activity Source: UniProtKB-EC

GO - Biological processi

  1. DNA biosynthetic process Source: InterPro
  2. DNA ligation involved in DNA repair Source: InterPro
  3. DNA recombination Source: UniProtKB-KW
  4. DNA replication Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

LigaseUniRule annotation

Keywords - Biological processi

DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
Gene namesi
ORF Names:DICPUDRAFT_81260Imported
OrganismiDictyostelium purpureum (Slime mold)Imported
Taxonomic identifieri5786 [NCBI]
Taxonomic lineageiEukaryotaAmoebozoaMycetozoaDictyosteliidaDictyostelium
ProteomesiUP000001064: Unassembled WGS sequence

Family & Domainsi

Sequence similaritiesi

Belongs to the ATP-dependent DNA ligase family.UniRule annotation

Phylogenomic databases

InParanoidiF0ZSY6.
KOiK10776.
OMAiINTGAKF.

Family and domain databases

Gene3Di1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
3.40.50.10190. 2 hits.
InterProiIPR001357. BRCT_dom.
IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamiPF00533. BRCT. 1 hit.
PF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
PF12738. PTCB-BRCT. 1 hit.
[Graphical view]
SMARTiSM00292. BRCT. 2 hits.
[Graphical view]
SUPFAMiSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
SSF52113. SSF52113. 2 hits.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS50172. BRCT. 2 hits.
PS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F0ZSY6-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSEDKSGSLY SLSKLCEKLK EESTHSGKTQ IISSFCKVFN GDLYLLAKLL
60 70 80 90 100
LCKEDKRVFR MRDKVMLKIC AHIWDADLDD MIADLDNGDF TETCKKFYIE
110 120 130 140 150
YGKYPEKSTL TLKQVDDFLD SLTLSGKFDE QVKIISSLLK KCTPQDFRLI
160 170 180 190 200
CRIIDSDLKI NTGAKFFLDA LHPNAYDAYK KANNLHGVIE KIQKHSFESD
210 220 230 240 250
EESDDERSSS SSSNKKKSKK SIDSDDSDNE KSSSKKKSKS KSKSFDVAIK
260 270 280 290 300
LMTPIKPMLP KAVKDVDDVA KSSSCFYSEI KYDGERIQIH KDGNKFSCFS
310 320 330 340 350
RNLKPLMPWK VDEVKQYIPK ATKANQMILD GEVLLMDTKT GIPLPFGTLG
360 370 380 390 400
AHKKKGFIDA TVCVFLFDIL YLDGKSLIHL PLEERREILE KNVTVVKHRV
410 420 430 440 450
EFSEVTIVKG IQEKYKLTNL LNRAFKEKLE GLVIKNADSI YEPGARHWIK
460 470 480 490 500
VKKDYIKGMA DSADLIAIGG YYGSGSFGGL VTVFLMACYD KVSKRYKTVV
510 520 530 540 550
KASGGLDDKT IDKLQPKIKE TMKKISKDHT KVPDWIDINK PYTPDFIVEH
560 570 580 590 600
PRDAMILEIE SAELTKTNYH TSGYSMRFPR IVRFREDKDY KTATNLQELM
610 620 630 640 650
ELGKDAKIIP TDDIEGEFDD ENLIAKRNKK KSLSITATTS TTTTTTTSSK
660 670 680 690 700
SKDKDQQQSD NEEEDSKTKD KLFYVGGDLT QPFSGSGDTS PNIFVLNYVD
710 720 730 740 750
NTDKWNNKGI SGAISKRFPK VVESFEKIKS GESKSEKVLE ENIDKEKKKI
760 770 780 790 800
FVCNLSCIVP PKSKDESYSF SLKHFKSAIK ESKGVIKNKN GSVHIAKPSF
810 820 830 840 850
SKPSWSEIEE VLIDELYDSG IKVFVHSIKS PPSVSKTSTL SSKTTTIDVS
860 870 880 890 900
VNNNNNNNKN ENENEKTSLK RDRDQMLEHE ILKELEEKEL EAPVFGNVNV
910 920 930 940 950
VFDQSVLDNQ KLAKKCERLI KILGGRVSEK WCAIKGLDKT THLICDDGES
960 970 980 990 1000
DLYHHVSRLG GAIAKTQWVE DCFNNDLLLP IDEIYCYVSK NGSSTSQNHS
1010 1020 1030 1040 1050
SKSLDTNTTK NSNAMQIDKL GESTSTSKKE EKQCKSSPSP TKKQHLLNIF
1060 1070 1080 1090 1100
SDCSIYLHEN VNDRDTLKRY IVAFGGDVVD QINEKTTHLI ASLPPNFSTV
1110 1120 1130 1140
KPKDLFKQFL QQNKTHNKKI GNSLWLWDSI NMGEVLDIKS YKLF
Length:1,144
Mass (Da):129,457
Last modified:May 3, 2011 - v1
Checksum:i9E6CFEC950E9ECED
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GL871165 Genomic DNA. Translation: EGC32964.1.
RefSeqiXP_003290530.1. XM_003290482.1.

Genome annotation databases

GeneIDi10507925.
KEGGidpp:DICPUDRAFT_81260.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GL871165 Genomic DNA. Translation: EGC32964.1 .
RefSeqi XP_003290530.1. XM_003290482.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 10507925.
KEGGi dpp:DICPUDRAFT_81260.

Phylogenomic databases

InParanoidi F0ZSY6.
KOi K10776.
OMAi INTGAKF.

Family and domain databases

Gene3Di 1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
3.40.50.10190. 2 hits.
InterProi IPR001357. BRCT_dom.
IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view ]
Pfami PF00533. BRCT. 1 hit.
PF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
PF12738. PTCB-BRCT. 1 hit.
[Graphical view ]
SMARTi SM00292. BRCT. 2 hits.
[Graphical view ]
SUPFAMi SSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
SSF52113. SSF52113. 2 hits.
TIGRFAMsi TIGR00574. dnl1. 1 hit.
PROSITEi PS50172. BRCT. 2 hits.
PS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: QSDP1Imported.

Entry informationi

Entry nameiF0ZSY6_DICPU
AccessioniPrimary (citable) accession number: F0ZSY6
Entry historyi
Integrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: May 3, 2011
Last modified: October 29, 2014
This is version 15 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3