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Protein

Thymidine kinase

Gene

DICPUDRAFT_49097

Organism
Dictyostelium purpureum (Slime mold)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + thymidine = ADP + thymidine 5'-phosphate.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei93Proton acceptorUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinaseUniRule annotation, Transferase
Biological processDNA synthesisUniRule annotation
LigandATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Thymidine kinaseUniRule annotation (EC:2.7.1.21UniRule annotation)
Gene namesi
ORF Names:DICPUDRAFT_49097Imported
OrganismiDictyostelium purpureum (Slime mold)Imported
Taxonomic identifieri5786 [NCBI]
Taxonomic lineageiEukaryotaAmoebozoaMycetozoaDictyosteliidaDictyostelium
Proteomesi
  • UP000001064 Componenti: Unassembled WGS sequence

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi5786.XP_003290301.1.

Family & Domainsi

Sequence similaritiesi

Belongs to the thymidine kinase family.UniRule annotation

Phylogenomic databases

eggNOGiKOG3125. Eukaryota.
COG1435. LUCA.
InParanoidiF0ZSA2.
KOiK00857.
OMAiCAGLDQD.

Family and domain databases

InterProiView protein in InterPro
IPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020633. Thymidine_kinase_CS.
PANTHERiPTHR11441. PTHR11441. 1 hit.
PfamiView protein in Pfam
PF00265. TK. 1 hit.
PIRSFiPIRSF035805. TK_cell. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiView protein in PROSITE
PS00603. TK_CELLULAR_TYPE. 1 hit.

Sequencei

Sequence statusi: Complete.

F0ZSA2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAIIPTVVGK IQVIFGPMFS GKTTELIRRI KRFNFANKKC LLIKYSKDTR
60 70 80 90 100
YNDNIDKSFL VTHDKQNYQA FPCSILEDIR EQAEKYDVIG IDEGQFFPDV
110 120 130 140 150
VQFSEELANQ GKTVIIAALD GTFQRKPFAS VIDLVSKAEV ITKLTAVCMV
160 170 180 190 200
CYNDAAFSKR IVDDDNIELI GGIDKYISVC RGCYHKDTSM KTLKSVRNVH
210 220 230
DKALSGAVVA AHDQFYQDGP QNMAVDDIHL NNDY
Length:234
Mass (Da):26,378
Last modified:May 3, 2011 - v1
Checksum:i5DE7E252765CE172
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GL871154 Genomic DNA. Translation: EGC33181.1.
RefSeqiXP_003290301.1. XM_003290253.1.

Genome annotation databases

EnsemblProtistsiEGC33181; EGC33181; DICPUDRAFT_49097.
GeneIDi10504656.
KEGGidpp:DICPUDRAFT_49097.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiF0ZSA2_DICPU
AccessioniPrimary (citable) accession number: F0ZSA2
Entry historyiIntegrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: May 3, 2011
Last modified: July 5, 2017
This is version 33 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported