Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Glutamate decarboxylase

Gene

gadA

Organism
Dictyostelium purpureum (Slime mold)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamate = 4-aminobutanoate + CO2.UniRule annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotation

GO - Molecular functioni

  1. glutamate decarboxylase activity Source: UniProtKB-EC
  2. pyridoxal phosphate binding Source: InterPro

GO - Biological processi

  1. glutamate metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

DecarboxylaseUniRule annotation, Lyase

Keywords - Ligandi

Pyridoxal phosphateUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate decarboxylaseUniRule annotation (EC:4.1.1.15UniRule annotation)
Gene namesi
Name:gadAImported
ORF Names:DICPUDRAFT_146669Imported
OrganismiDictyostelium purpureum (Slime mold)Imported
Taxonomic identifieri5786 [NCBI]
Taxonomic lineageiEukaryotaAmoebozoaMycetozoaDictyosteliidaDictyostelium
ProteomesiUP000001064: Unassembled WGS sequence

Family & Domainsi

Sequence similaritiesi

Belongs to the group II decarboxylase family.UniRule annotation

Phylogenomic databases

InParanoidiF0Z6K2.
KOiK01580.
OMAiDPDLVWD.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PANTHERiPTHR11999:SF1. PTHR11999:SF1. 1 hit.
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.

Sequencei

Sequence statusi: Complete.

F0Z6K2-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSLHSIKSEN TKEKKGNSNK YKRCYDLYAE KSATHPINKY KINDHPTDPD
60 70 80 90 100
LSKNLILDEL LLDGNAKQNL ATFCQTDVDI NIHTLMDKCI DKNMIDKDEY
110 120 130 140 150
PQTAEIESRC VHMIADLWNS PDSANTIGCS TTGSSEAAML GGLALKWKWR
160 170 180 190 200
EQRKKEGKPC DRPNLITGPV QICWHKFVLY FDIELREIPM ENGRLLMSPE
210 220 230 240 250
EVLKRCDENT IGVVPTLGVT FTLQYENVRA ISDALDKYHK ETGLDIPIHV
260 270 280 290 300
DAASGGFVAP FITPDLVWDF RLPRVKSINA SGHKYGLSPL GVGWVIWRGK
310 320 330 340 350
EDIHKDLIFN VNYLGGNMPT FSLNFSRPGG QIVSQYYNFI RHGREGYRAI
360 370 380 390 400
HQACIDHGVY IGEEIKKMGI FDLIYDGKGA LPGVCWLLKK DAKVKFNLFD
410 420 430 440 450
LSDRMKTRGW QIASYTLPKN AESMIITRVL IRHGFSRDMA SLLIDDIKRC
460 470
LEYFEKHPLV KPLSKEEGEG FHH
Length:473
Mass (Da):53,824
Last modified:May 3, 2011 - v1
Checksum:i149F8E5CB2943A56
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GL870942 Genomic DNA. Translation: EGC40506.1.
RefSeqiXP_003283053.1. XM_003283005.1.

Genome annotation databases

GeneIDi10503472.
KEGGidpp:DICPUDRAFT_146669.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GL870942 Genomic DNA. Translation: EGC40506.1.
RefSeqiXP_003283053.1. XM_003283005.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi10503472.
KEGGidpp:DICPUDRAFT_146669.

Phylogenomic databases

InParanoidiF0Z6K2.
KOiK01580.
OMAiDPDLVWD.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PANTHERiPTHR11999:SF1. PTHR11999:SF1. 1 hit.
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: QSDP1Imported.

Entry informationi

Entry nameiF0Z6K2_DICPU
AccessioniPrimary (citable) accession number: F0Z6K2
Entry historyi
Integrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: May 3, 2011
Last modified: February 4, 2015
This is version 17 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.