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F0VWJ2 (F0VWJ2_STRG2) Unreviewed, UniProtKB/TrEMBL

Last modified May 29, 2013. Version 18. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Isocitrate dehydrogenase [NADP] RuleBase RU004446
EC=1.1.1.42 RuleBase RU004446
Gene names
Name:icd EMBL CBZ47839.1
Ordered Locus Names:SGGBAA2069_c06670 EMBL CBZ47839.1
OrganismStreptococcus gallolyticus (strain ATCC BAA-2069) [Complete proteome] [HAMAP] EMBL CBZ47839.1
Taxonomic identifier990317 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacilli › Lactobacillales › Streptococcaceae › Streptococcus ›

Protein attributes

Sequence length391 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH. RuleBase RU004446

Cofactor

Binds 1 magnesium or manganese ion per subunit By similarity. RuleBase RU004446

Sequence similarities

Belongs to the isocitrate and isopropylmalate dehydrogenases family. RuleBase RU004443

Sequences

Sequence LengthMass (Da)Tools
F0VWJ2 [UniParc].

Last modified May 3, 2011. Version 1.
Checksum: 8D019B4284BB67FE

FASTA39142,561
        10         20         30         40         50         60 
MADKIILENG HLTVSNNPII PFIEGDGVGR DIWKNARAVF DAAIDKAYQG QKKVEWLELL 

        70         80         90        100        110        120 
AGKKAHEATG EWLPEATLET IKEDLVAIKG PLETPVGGGI RSLNVALRQE LDLYACVRPV 

       130        140        150        160        170        180 
RYFKGIESPL KEPEKTGITI FRENTEDIYA GIEWNAGTEE VKKVIDFLQN EMSVSKIRFP 

       190        200        210        220        230        240 
ETSSIGIKPI SQEGSERLIR SAIEYALANN LTKVTLVHKG NIQKFTEGGF RSWGYDLAKR 

       250        260        270        280        290        300 
EYADELASGK LVINDIIADN FLQQILLNPE KFDVVALTNL NGDYASDALA AQVGGIGISP 

       310        320        330        340        350        360 
GANINYLTGH AIFEATHGTA PDIAGKDIAN PCSVLLSGCM LFDYIGWTEV ASLITAAIEK 

       370        380        390 
TFAQGQFTAD LAQGKVACST SEFAAKLIEN L

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References

[1]"Complete genome and comparative analysis of Streptococcus gallolyticus subsp. gallolyticus, an emerging pathogen of infective endocarditis."
Hinse D., Vollmer T., Ruckert C., Blom J., Kalinowski J., Knabbe C., Dreier J.
BMC Genomics 12:400-400(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-2069 EMBL CBZ47839.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		FR824043 Genomic DNA. Translation: CBZ47839.1.
RefSeqYP_004287583.1. NC_015215.1.

3D structure databases

ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCBZ47839; CBZ47839; SGGBAA2069_c06670.
GeneID10295496.
KEGGsgg:SGGBAA2069_c06670.
PATRIC47027129. VBIStrGal182109_0660.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK00031.

Enzyme and pathway databases

BioCycSGAL990317:GI5F-756-MONOMER.

Family and domain databases

Gene3D3.40.718.10. 1 hit.
InterProIPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PANTHERPTHR11835. PTHR11835. 1 hit.
PfamPF00180. Iso_dh. 1 hit.
[Graphical view]
PROSITEPS00470. IDH_IMDH. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameF0VWJ2_STRG2
AccessionPrimary (citable) accession number: F0VWJ2
Entry history
Integrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: May 3, 2011
Last modified: May 29, 2013
This is version 18 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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