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F0VSU0

- F0VSU0_STRG2

UniProt

F0VSU0 - F0VSU0_STRG2

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Protein

Alanine racemase

Gene

alr

Organism
Streptococcus gallolyticus (strain ATCC BAA-2069)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

Catalytic activityi

L-alanine = D-alanine.UniRule annotationSAAS annotation

Cofactori

Note: Pyridoxal phosphate.UniRule annotationSAAS annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei40 – 401Proton acceptor; specific for D-alanineUniRule annotation
Binding sitei136 – 1361SubstrateUniRule annotation
Active sitei263 – 2631Proton acceptor; specific for L-alanineUniRule annotation
Binding sitei310 – 3101Substrate; via amide nitrogenUniRule annotation

GO - Molecular functioni

  1. alanine racemase activity Source: UniProtKB-HAMAP
  2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-alanine biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotation

Keywords - Ligandi

Pyridoxal phosphateUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciSGAL990317:GI5F-1935-MONOMER.
UniPathwayiUPA00042; UER00497.

Names & Taxonomyi

Protein namesi
Recommended name:
Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
Gene namesi
Name:alrImported
Ordered Locus Names:SGGBAA2069_c18400Imported
OrganismiStreptococcus gallolyticus (strain ATCC BAA-2069)Imported
Taxonomic identifieri990317 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
ProteomesiUP000007495: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei40 – 401N6-(pyridoxal phosphate)lysineUniRule annotation

Structurei

3D structure databases

ProteinModelPortaliF0VSU0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the alanine racemase family.UniRule annotation

Phylogenomic databases

KOiK01775.
OMAiIYSHLAL.

Family and domain databases

Gene3Di2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPiMF_01201. Ala_racemase.
InterProiIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamiPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSiPR00992. ALARACEMASE.
SMARTiSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMiSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsiTIGR00492. alr. 1 hit.
PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F0VSU0-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MISSLHRPTK AVIDLDAICQ NIDAVKANIP QDKKAFAVVK ANAYGHGATN
60 70 80 90 100
VAQAIHHLVD GFCVSNIDEA LELREAGIEE TILILGVIMP DEVALARDYH
110 120 130 140 150
VTLTVASQEW LDLANEQGIS LAGLDVHLKV DSGMGRIGVR SLDEAENVIA
160 170 180 190 200
NLKKSGANVA GIFTHFATAD EADDTKFNEQ LEFFTNLVNN LSDKPAIVHA
210 220 230 240 250
SNSATSIWHS ETIFNLVRLG IVMYGLNPSG TELDLPYPLK PALSLESSLV
260 270 280 290 300
HVKTIPAGAT VGYGATYTAQ KEEYIATVPI GYADGWTRDL QGFSVLVNGE
310 320 330 340 350
FCEIVGRVSM DQITIRLPEK LPIGTKVTLI GQEGSKVISA TDLAQKRGTI
360
NYEVLCLLSD RIPRVYSK
Length:368
Mass (Da):39,781
Last modified:May 3, 2011 - v1
Checksum:iE911CFF99FF25A5A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FR824043 Genomic DNA. Translation: CBZ49012.1.
RefSeqiYP_004288756.1. NC_015215.1.

Genome annotation databases

EnsemblBacteriaiCBZ49012; CBZ49012; SGGBAA2069_c18400.
GeneIDi10296184.
KEGGisgg:SGGBAA2069_c18400.
PATRICi47029492. VBIStrGal182109_1831.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FR824043 Genomic DNA. Translation: CBZ49012.1 .
RefSeqi YP_004288756.1. NC_015215.1.

3D structure databases

ProteinModelPortali F0VSU0.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CBZ49012 ; CBZ49012 ; SGGBAA2069_c18400 .
GeneIDi 10296184.
KEGGi sgg:SGGBAA2069_c18400.
PATRICi 47029492. VBIStrGal182109_1831.

Phylogenomic databases

KOi K01775.
OMAi IYSHLAL.

Enzyme and pathway databases

UniPathwayi UPA00042 ; UER00497 .
BioCyci SGAL990317:GI5F-1935-MONOMER.

Family and domain databases

Gene3Di 2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPi MF_01201. Ala_racemase.
InterProi IPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view ]
Pfami PF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view ]
PRINTSi PR00992. ALARACEMASE.
SMARTi SM01005. Ala_racemase_C. 1 hit.
[Graphical view ]
SUPFAMi SSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsi TIGR00492. alr. 1 hit.
PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete genome and comparative analysis of Streptococcus gallolyticus subsp. gallolyticus, an emerging pathogen of infective endocarditis."
    Hinse D., Vollmer T., Rueckert C., Blom J., Kalinowski J., Knabbe C., Dreier J.
    BMC Genomics 12:400-400(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-2069Imported.

Entry informationi

Entry nameiF0VSU0_STRG2
AccessioniPrimary (citable) accession number: F0VSU0
Entry historyi
Integrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: May 3, 2011
Last modified: November 26, 2014
This is version 30 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3