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Protein

Elongation factor Tu

Gene

tuf

Organism
Mycoplasma suis (strain KI_3806)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi19 – 26GTPUniRule annotation8
Nucleotide bindingi81 – 85GTPUniRule annotation5
Nucleotide bindingi136 – 139GTPUniRule annotation4

GO - Molecular functioni

Keywordsi

Molecular functionElongation factorUniRule annotationImported
Biological processProtein biosynthesis
LigandGTP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Elongation factor TuUniRule annotation
Short name:
EF-TuUniRule annotation
Gene namesi
Name:tufUniRule annotationImported
ORF Names:MSUIS_02390Imported
OrganismiMycoplasma suis (strain KI_3806)Imported
Taxonomic identifieri708248 [NCBI]
Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma
Proteomesi
  • UP000008645 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi708248.Msui02390.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini10 – 204Tr-type G (guanine nucleotide-binding)InterPro annotationAdd BLAST195

Sequence similaritiesi

Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CGV. Bacteria.
COG0050. LUCA.
KOiK02358.
OMAiYGHIDCP.
OrthoDBiPOG091H00LA.

Family and domain databases

CDDicd03697. EFTU_II. 1 hit.
HAMAPiMF_00118_B. EF_Tu_B. 1 hit.
InterProiView protein in InterPro
IPR004161. EFTu-like_2.
IPR033720. EFTU_2.
IPR031157. G_TR_CS.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR000795. TF_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
PfamiView protein in Pfam
PF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
PRINTSiPR00315. ELONGATNFCT.
SUPFAMiSSF50447. SSF50447. 1 hit.
SSF50465. SSF50465. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEiView protein in PROSITE
PS00301. G_TR_1. 1 hit.
PS51722. G_TR_2. 1 hit.

Sequencei

Sequence statusi: Complete.

F0V3B0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSKVKFSREK EHINVGTIGH IDHGKTTLTA AICTYCSKQG RGEARDYASI
60 70 80 90 100
DRAPEERERG ITINTTHVEY ETETRHYAHV DCPGHSDYIK NMIVGAAQVD
110 120 130 140 150
GAILVVSATD GPMPQTREHI LLAKQVGVQK IVVFLNKCDT VTDAEMLDLV
160 170 180 190 200
EMEIKELLTS YDFDGDNTPV IRGSALRALE GDPAAEKSIQ DLLDQLDTYI
210 220 230 240 250
PLPIRDIEKP FLLSIEDVLT ITGRGTVVTG RCERGELKVG EEVEIVGFGE
260 270 280 290 300
TRKAIVTGIE MFRKPLEKVI PGDNAGILLR GIDKNEVTRG QVLSKPKSIT
310 320 330 340 350
PHSSFKAEVY ALKKEEGGRH SAFGSGYKPQ FYFRTTDVTG EITLPDGVEM
360 370 380 390
VMPGDHSPII VKLISSVAVE QGFKFSIREG GKTIGAGTVT EILE
Length:394
Mass (Da):43,197
Last modified:May 3, 2011 - v1
Checksum:iD75DBAEB87541B4A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FQ790233 Genomic DNA. Translation: CBZ40332.1.
RefSeqiWP_013608939.1. NC_015153.1.

Genome annotation databases

EnsemblBacteriaiCBZ40332; CBZ40332; MSUIS_02390.
KEGGimsk:MSUIS_02390.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiF0V3B0_MYCS3
AccessioniPrimary (citable) accession number: F0V3B0
Entry historyiIntegrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: May 3, 2011
Last modified: July 5, 2017
This is version 43 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported