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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Lactobacillus amylovorus
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotationSAAS annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei138UniRule annotation1
Active sitei575UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotationImported

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, PyruvateImported

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
Ordered Locus Names:LAC30SC_05825Imported
OrganismiLactobacillus amylovorusImported
Taxonomic identifieri1604 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesLactobacillaceaeLactobacillus
Proteomesi
  • UP000007491 Componenti: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi891391.LAC30SC_05825.

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4105CCA. Bacteria.
COG2352. LUCA.
KOiK01595.
OrthoDBiPOG091H040O.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1. 1 hit.
InterProiIPR021135. PEP_COase.
IPR022805. PEP_COase_bac/pln-type.
IPR018129. PEP_COase_Lys_AS.
IPR033129. PEPCASE_His_AS.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F0TF11-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTFTKLENSG DQAVVAEEVK ILTNLLNEST RQLIGDEKFA KIQDLINISA
60 70 80 90 100
SKDQRQLEEK ISSLNNREMI VVARYFATLP LLINISEDVE LASKVNVFNN
110 120 130 140 150
TDQDYLGKLS DTIDLVAKKD DAKRILENVN VVPVLTAHPT QIQRKTVLEL
160 170 180 190 200
TDKIHHLLRS YRDGKNGTIN QKEWTEQLRA CIEILMQTDI IRGHKLKVSN
210 220 230 240 250
EITNVLAYYP KALIPAITKF TARYKELAKE HDLTLDHATP ITMGMWIGGD
260 270 280 290 300
RDGNPYVTAD TLELSATLQS QVIFEYYMKE LKKLYRAISL STSYMHPSAA
310 320 330 340 350
VEKLSELSND DSPFRTNEPY RRAFYYIESR LVHTEKQLLG VVDKNIFIKP
360 370 380 390 400
RDLENLENIP VYNDPQEFKA DLETIKASLD EDHDQAVTHS FFTEILEAID
410 420 430 440 450
VFGFHLATID MRQDSSVNEA CVAELLKSAG ICDDYSDLSE DEKIKLLLNE
460 470 480 490 500
LENDPRNLHA NNKPKSELLQ KELKIYKTAR QLKDRLGEDV IKQHIISHTE
510 520 530 540 550
SVSDMLEQAV MLKEYDLLDN EKARVQVVPL FETVEDLLNA REIITEYLNF
560 570 580 590 600
PIVKKWLASQ NNYQEIMLGY SDSNKDGGYL ASCWNLYKAQ RDLTAIGEKM
610 620 630 640 650
GVKITYMHGR GGTVGRGGGP SYDAITAQPF KSINDRIRMT EQGEIIQNKY
660 670 680 690 700
GNKDTAYYNL EMLASAAIDR MVSKQIVSED HIQDFRSSMD QIVDESNKIY
710 720 730 740 750
RELVFENPAF LDYFFQATPI KEISNLNIGS RPASRKKLTD FSGLRAIPWV
760 770 780 790 800
FSWSQSRIMF PGWYGVGSAF KHFIDADPAN LKELQEMYKG WPFFNSLLAN
810 820 830 840 850
VDMVLSKSNM DIAREYANLC DDEETKKVFD IIYKEWKLTK KVILQIENHD
860 870 880 890 900
ELLAEAPVLK QSLDYRMPYF NILNYIQIEM IKRGREDEIQ GVYHSIIPIT
910
INGVASGLRN SG
Length:912
Mass (Da):104,413
Last modified:May 3, 2011 - v1
Checksum:i726990BEF20E4B12
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002559 Genomic DNA. Translation: ADZ07305.1.

Genome annotation databases

EnsemblBacteriaiADZ07305; ADZ07305; LAC30SC_05825.
KEGGilai:LAC30SC_05825.
PATRICi46965105. VBILacAci171603_1154.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002559 Genomic DNA. Translation: ADZ07305.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi891391.LAC30SC_05825.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiADZ07305; ADZ07305; LAC30SC_05825.
KEGGilai:LAC30SC_05825.
PATRICi46965105. VBILacAci171603_1154.

Phylogenomic databases

eggNOGiENOG4105CCA. Bacteria.
COG2352. LUCA.
KOiK01595.
OrthoDBiPOG091H040O.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1. 1 hit.
InterProiIPR021135. PEP_COase.
IPR022805. PEP_COase_bac/pln-type.
IPR018129. PEP_COase_Lys_AS.
IPR033129. PEPCASE_His_AS.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiF0TF11_LACAM
AccessioniPrimary (citable) accession number: F0TF11
Entry historyi
Integrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: May 3, 2011
Last modified: November 30, 2016
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.