Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

F0T408

- F0T408_CHLP6

UniProt

F0T408 - F0T408_CHLP6

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Acetyltransferase component of pyruvate dehydrogenase complex

Gene

CPSIT_0516

Organism
Chlamydophila psittaci (strain ATCC VR-125 / 6BC) (Chlamydia psittaci)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.UniRule annotation

Catalytic activityi

Acetyl-CoA + enzyme N(6)-(dihydrolipoyl)lysine = CoA + enzyme N(6)-(S-acetyldihydrolipoyl)lysine.UniRule annotation

Cofactori

Protein has several cofactor binding sites:
  • Note: Binds 1 lipoyl cofactor covalently.UniRule annotation
  • Note: Binds 2 lipoyl cofactors covalently.UniRule annotation
  • Note: Binds 3 lipoyl cofactors covalently.UniRule annotation

GO - Molecular functioni

  1. dihydrolipoyllysine-residue acetyltransferase activity Source: UniProtKB-EC

GO - Biological processi

  1. pyruvate metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

AcyltransferaseUniRule annotationImported, Transferase

Keywords - Ligandi

PyruvateImported

Names & Taxonomyi

Protein namesi
Recommended name:
Acetyltransferase component of pyruvate dehydrogenase complexUniRule annotation (EC:2.3.1.12UniRule annotation)
Gene namesi
Ordered Locus Names:CPSIT_0516Imported, G5O_0512Imported
OrganismiChlamydophila psittaci (strain ATCC VR-125 / 6BC) (Chlamydia psittaci)Imported
Taxonomic identifieri331636 [NCBI]
Taxonomic lineageiBacteriaChlamydiaeChlamydialesChlamydiaceaeChlamydia/Chlamydophila groupChlamydia
ProteomesiUP000007489: Chromosome, UP000008336: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. pyruvate dehydrogenase complex Source: InterPro
Complete GO annotation...

Family & Domainsi

Sequence similaritiesi

Belongs to the 2-oxoacid dehydrogenase family.UniRule annotation
Contains 1 lipoyl-binding domain.UniRule annotation

Keywords - Domaini

LipoylUniRule annotation

Phylogenomic databases

KOiK00627.
OMAiMEMESYE.

Family and domain databases

Gene3Di3.30.559.10. 1 hit.
4.10.320.10. 1 hit.
InterProiIPR001078. 2-oxoacid_DH_actylTfrase.
IPR000089. Biotin_lipoyl.
IPR023213. CAT-like_dom.
IPR004167. E3-bd.
IPR006257. LAT1.
IPR011053. Single_hybrid_motif.
[Graphical view]
PfamiPF00198. 2-oxoacid_dh. 1 hit.
PF00364. Biotin_lipoyl. 1 hit.
PF02817. E3_binding. 1 hit.
[Graphical view]
SUPFAMiSSF47005. SSF47005. 1 hit.
SSF51230. SSF51230. 1 hit.
TIGRFAMsiTIGR01349. PDHac_trf_mito. 1 hit.
PROSITEiPS50968. BIOTINYL_LIPOYL. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F0T408-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MISLLKMPKL SPTMEVGTIV KWHKNNGDKI EFGDVLLEVS TDKAVLEHTA
60 70 80 90 100
NEEGWFRDCL VKEGTKVHIG TPIAVISSEK DEDFNLDTIL PKTPEPELPV
110 120 130 140 150
ENVQLVEEEV TKVQPSVAPM QLAFQFKPEP PLSKPLSLKV DSSKSPISPL
160 170 180 190 200
AKRVAKEKNL DISGIKGSGP GGRIVEKDLD KAPTKGIAGF GYPEAPEVHP
210 220 230 240 250
GSYHEETLSP IRDIIAQRLQ AAKASIPHFY VTQKVYASPL LALLKELQAQ
260 270 280 290 300
GIKLSINDCI VRACALALKE FPEVNSGFNS VDNKIVRFET IDISIAVAIP
310 320 330 340 350
DGVITPIVRC ADRKNIGMIS AEIKSLASKA KSQSLKEEEY KGGSFCVSNL
360 370 380 390 400
GMTGITAFTA IINPPQAAIL AVGSVQEEPI VINGEILVGS TCILTLSIDH
410 420
RVIDGYPAAM FMKRLQKILE APSILLLN
Length:428
Mass (Da):46,397
Last modified:May 3, 2011 - v1
Checksum:i98684E7ED24C6699
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002549 Genomic DNA. Translation: ADZ18278.1.
CP002586 Genomic DNA. Translation: AEB55501.1.
RefSeqiYP_004422321.1. NC_015470.1.
YP_005663174.1. NC_017287.1.

Genome annotation databases

EnsemblBacteriaiADZ18278; ADZ18278; CPSIT_0516.
AEB55501; AEB55501; G5O_0512.
GeneIDi10602218.
12242934.
KEGGichb:G5O_0512.
chp:CPSIT_0516.
PATRICi47105634. VBIChlPsi52874_0496.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002549 Genomic DNA. Translation: ADZ18278.1 .
CP002586 Genomic DNA. Translation: AEB55501.1 .
RefSeqi YP_004422321.1. NC_015470.1.
YP_005663174.1. NC_017287.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ADZ18278 ; ADZ18278 ; CPSIT_0516 .
AEB55501 ; AEB55501 ; G5O_0512 .
GeneIDi 10602218.
12242934.
KEGGi chb:G5O_0512.
chp:CPSIT_0516.
PATRICi 47105634. VBIChlPsi52874_0496.

Phylogenomic databases

KOi K00627.
OMAi MEMESYE.

Family and domain databases

Gene3Di 3.30.559.10. 1 hit.
4.10.320.10. 1 hit.
InterProi IPR001078. 2-oxoacid_DH_actylTfrase.
IPR000089. Biotin_lipoyl.
IPR023213. CAT-like_dom.
IPR004167. E3-bd.
IPR006257. LAT1.
IPR011053. Single_hybrid_motif.
[Graphical view ]
Pfami PF00198. 2-oxoacid_dh. 1 hit.
PF00364. Biotin_lipoyl. 1 hit.
PF02817. E3_binding. 1 hit.
[Graphical view ]
SUPFAMi SSF47005. SSF47005. 1 hit.
SSF51230. SSF51230. 1 hit.
TIGRFAMsi TIGR01349. PDHac_trf_mito. 1 hit.
PROSITEi PS50968. BIOTINYL_LIPOYL. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Full-length de novo sequence of the Chlamydophila psittaci type strain, 6BC."
    Voigt A., Schofl G., Heidrich A., Sachse K., Saluz H.P.
    J. Bacteriol. 193:2662-2663(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 6BCImported and ATCC VR-125 / 6BC.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 6BCImported and ATCC VR-125 / 6BCImported.
  3. "Full length de novo sequence of the Chlamydophyla psittaci reference strain 6BC."
    Voigt A., Schofl G., Heidrich A., Sachse K., Saluz H.P.
    Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: 6BC.
  4. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: 6BCImported.

Entry informationi

Entry nameiF0T408_CHLP6
AccessioniPrimary (citable) accession number: F0T408
Entry historyi
Integrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: May 3, 2011
Last modified: November 26, 2014
This is version 23 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3