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F0T408

- F0T408_CHLP6

UniProt

F0T408 - F0T408_CHLP6

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Protein
Acetyltransferase component of pyruvate dehydrogenase complex
Gene
CPSIT_0516, G5O_0512
Organism
Chlamydophila psittaci (strain ATCC VR-125 / 6BC) (Chlamydia psittaci)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2 By similarity.UniRule annotation

Catalytic activityi

Acetyl-CoA + enzyme N(6)-(dihydrolipoyl)lysine = CoA + enzyme N(6)-(S-acetyldihydrolipoyl)lysine.UniRule annotation

Cofactori

Binds 1 lipoyl cofactor covalently By similarity.UniRule annotation
Binds 2 lipoyl cofactors covalently By similarity.UniRule annotation
Binds 3 lipoyl cofactors covalently By similarity.UniRule annotation

GO - Molecular functioni

  1. dihydrolipoyllysine-residue acetyltransferase activity Source: UniProtKB-EC
Complete GO annotation...

GO - Biological processi

  1. pyruvate metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

AcyltransferaseUniRule annotationImported, Transferase

Keywords - Ligandi

PyruvateImported

Names & Taxonomyi

Protein namesi
Recommended name:
Acetyltransferase component of pyruvate dehydrogenase complexUniRule annotation (EC:2.3.1.12UniRule annotation)
Gene namesi
Ordered Locus Names:CPSIT_0516Imported, G5O_0512Imported
OrganismiChlamydophila psittaci (strain ATCC VR-125 / 6BC) (Chlamydia psittaci)Imported
Taxonomic identifieri331636 [NCBI]
Taxonomic lineageiBacteriaChlamydiaeChlamydialesChlamydiaceaeChlamydia/Chlamydophila groupChlamydia
ProteomesiUP000007489: Chromosome, UP000008336: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. pyruvate dehydrogenase complex Source: InterPro
Complete GO annotation...

Family & Domainsi

Sequence similaritiesi

Belongs to the 2-oxoacid dehydrogenase family.UniRule annotation
Contains 1 lipoyl-binding domain.UniRule annotation

Keywords - Domaini

LipoylUniRule annotation

Phylogenomic databases

KOiK00627.
OMAiMEMESYE.

Family and domain databases

Gene3Di3.30.559.10. 1 hit.
4.10.320.10. 1 hit.
InterProiIPR001078. 2-oxoacid_DH_actylTfrase.
IPR000089. Biotin_lipoyl.
IPR023213. CAT-like_dom.
IPR004167. E3-bd.
IPR006257. LAT1.
IPR011053. Single_hybrid_motif.
[Graphical view]
PfamiPF00198. 2-oxoacid_dh. 1 hit.
PF00364. Biotin_lipoyl. 1 hit.
PF02817. E3_binding. 1 hit.
[Graphical view]
SUPFAMiSSF47005. SSF47005. 1 hit.
SSF51230. SSF51230. 1 hit.
TIGRFAMsiTIGR01349. PDHac_trf_mito. 1 hit.
PROSITEiPS50968. BIOTINYL_LIPOYL. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F0T408-1 [UniParc]FASTAAdd to Basket

« Hide

MISLLKMPKL SPTMEVGTIV KWHKNNGDKI EFGDVLLEVS TDKAVLEHTA    50
NEEGWFRDCL VKEGTKVHIG TPIAVISSEK DEDFNLDTIL PKTPEPELPV 100
ENVQLVEEEV TKVQPSVAPM QLAFQFKPEP PLSKPLSLKV DSSKSPISPL 150
AKRVAKEKNL DISGIKGSGP GGRIVEKDLD KAPTKGIAGF GYPEAPEVHP 200
GSYHEETLSP IRDIIAQRLQ AAKASIPHFY VTQKVYASPL LALLKELQAQ 250
GIKLSINDCI VRACALALKE FPEVNSGFNS VDNKIVRFET IDISIAVAIP 300
DGVITPIVRC ADRKNIGMIS AEIKSLASKA KSQSLKEEEY KGGSFCVSNL 350
GMTGITAFTA IINPPQAAIL AVGSVQEEPI VINGEILVGS TCILTLSIDH 400
RVIDGYPAAM FMKRLQKILE APSILLLN 428
Length:428
Mass (Da):46,397
Last modified:May 3, 2011 - v1
Checksum:i98684E7ED24C6699
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002549 Genomic DNA. Translation: ADZ18278.1.
CP002586 Genomic DNA. Translation: AEB55501.1.
RefSeqiYP_004422321.1. NC_015470.1.
YP_005663174.1. NC_017287.1.

Genome annotation databases

EnsemblBacteriaiADZ18278; ADZ18278; CPSIT_0516.
AEB55501; AEB55501; G5O_0512.
GeneIDi10602218.
12242934.
KEGGichb:G5O_0512.
chp:CPSIT_0516.
PATRICi47105634. VBIChlPsi52874_0496.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002549 Genomic DNA. Translation: ADZ18278.1 .
CP002586 Genomic DNA. Translation: AEB55501.1 .
RefSeqi YP_004422321.1. NC_015470.1.
YP_005663174.1. NC_017287.1.

3D structure databases

ModBasei Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ADZ18278 ; ADZ18278 ; CPSIT_0516 .
AEB55501 ; AEB55501 ; G5O_0512 .
GeneIDi 10602218.
12242934.
KEGGi chb:G5O_0512.
chp:CPSIT_0516.
PATRICi 47105634. VBIChlPsi52874_0496.

Phylogenomic databases

KOi K00627.
OMAi MEMESYE.

Family and domain databases

Gene3Di 3.30.559.10. 1 hit.
4.10.320.10. 1 hit.
InterProi IPR001078. 2-oxoacid_DH_actylTfrase.
IPR000089. Biotin_lipoyl.
IPR023213. CAT-like_dom.
IPR004167. E3-bd.
IPR006257. LAT1.
IPR011053. Single_hybrid_motif.
[Graphical view ]
Pfami PF00198. 2-oxoacid_dh. 1 hit.
PF00364. Biotin_lipoyl. 1 hit.
PF02817. E3_binding. 1 hit.
[Graphical view ]
SUPFAMi SSF47005. SSF47005. 1 hit.
SSF51230. SSF51230. 1 hit.
TIGRFAMsi TIGR01349. PDHac_trf_mito. 1 hit.
PROSITEi PS50968. BIOTINYL_LIPOYL. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Full-length de novo sequence of the Chlamydophila psittaci type strain, 6BC."
    Voigt A., Schofl G., Heidrich A., Sachse K., Saluz H.P.
    J. Bacteriol. 193:2662-2663(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 6BCImported and ATCC VR-125 / 6BC.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 6BCImported and ATCC VR-125 / 6BC.
  3. "Full length de novo sequence of the Chlamydophyla psittaci reference strain 6BC."
    Voigt A., Schofl G., Heidrich A., Sachse K., Saluz H.P.
    Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: 6BC.
  4. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: 6BCImported.

Entry informationi

Entry nameiF0T408_CHLP6
AccessioniPrimary (citable) accession number: F0T408
Entry historyi
Integrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: May 3, 2011
Last modified: July 9, 2014
This is version 20 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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