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F0T408

- F0T408_CHLP6

UniProt

F0T408 - F0T408_CHLP6

Protein

Acetyltransferase component of pyruvate dehydrogenase complex

Gene

CPSIT_0516

Organism
Chlamydophila psittaci (strain ATCC VR-125 / 6BC) (Chlamydia psittaci)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 21 (01 Oct 2014)
      Sequence version 1 (03 May 2011)
      Previous versions | rss
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    Functioni

    The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.UniRule annotation

    Catalytic activityi

    Acetyl-CoA + enzyme N(6)-(dihydrolipoyl)lysine = CoA + enzyme N(6)-(S-acetyldihydrolipoyl)lysine.UniRule annotation

    Cofactori

    Binds 1 lipoyl cofactor covalently.UniRule annotation
    Binds 2 lipoyl cofactors covalently.UniRule annotation
    Binds 3 lipoyl cofactors covalently.UniRule annotation

    GO - Molecular functioni

    1. dihydrolipoyllysine-residue acetyltransferase activity Source: UniProtKB-EC

    GO - Biological processi

    1. pyruvate metabolic process Source: InterPro

    Keywords - Molecular functioni

    AcyltransferaseUniRule annotationImported, Transferase

    Keywords - Ligandi

    PyruvateImported

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Acetyltransferase component of pyruvate dehydrogenase complexUniRule annotation (EC:2.3.1.12UniRule annotation)
    Gene namesi
    Ordered Locus Names:CPSIT_0516Imported, G5O_0512Imported
    OrganismiChlamydophila psittaci (strain ATCC VR-125 / 6BC) (Chlamydia psittaci)Imported
    Taxonomic identifieri331636 [NCBI]
    Taxonomic lineageiBacteriaChlamydiaeChlamydialesChlamydiaceaeChlamydia/Chlamydophila groupChlamydia
    ProteomesiUP000007489: Chromosome, UP000008336: Chromosome

    Subcellular locationi

    GO - Cellular componenti

    1. pyruvate dehydrogenase complex Source: InterPro

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the 2-oxoacid dehydrogenase family.UniRule annotation
    Contains 1 lipoyl-binding domain.UniRule annotation

    Keywords - Domaini

    LipoylUniRule annotation

    Phylogenomic databases

    KOiK00627.
    OMAiMEMESYE.

    Family and domain databases

    Gene3Di3.30.559.10. 1 hit.
    4.10.320.10. 1 hit.
    InterProiIPR001078. 2-oxoacid_DH_actylTfrase.
    IPR000089. Biotin_lipoyl.
    IPR023213. CAT-like_dom.
    IPR004167. E3-bd.
    IPR006257. LAT1.
    IPR011053. Single_hybrid_motif.
    [Graphical view]
    PfamiPF00198. 2-oxoacid_dh. 1 hit.
    PF00364. Biotin_lipoyl. 1 hit.
    PF02817. E3_binding. 1 hit.
    [Graphical view]
    SUPFAMiSSF47005. SSF47005. 1 hit.
    SSF51230. SSF51230. 1 hit.
    TIGRFAMsiTIGR01349. PDHac_trf_mito. 1 hit.
    PROSITEiPS50968. BIOTINYL_LIPOYL. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    F0T408-1 [UniParc]FASTAAdd to Basket

    « Hide

    MISLLKMPKL SPTMEVGTIV KWHKNNGDKI EFGDVLLEVS TDKAVLEHTA    50
    NEEGWFRDCL VKEGTKVHIG TPIAVISSEK DEDFNLDTIL PKTPEPELPV 100
    ENVQLVEEEV TKVQPSVAPM QLAFQFKPEP PLSKPLSLKV DSSKSPISPL 150
    AKRVAKEKNL DISGIKGSGP GGRIVEKDLD KAPTKGIAGF GYPEAPEVHP 200
    GSYHEETLSP IRDIIAQRLQ AAKASIPHFY VTQKVYASPL LALLKELQAQ 250
    GIKLSINDCI VRACALALKE FPEVNSGFNS VDNKIVRFET IDISIAVAIP 300
    DGVITPIVRC ADRKNIGMIS AEIKSLASKA KSQSLKEEEY KGGSFCVSNL 350
    GMTGITAFTA IINPPQAAIL AVGSVQEEPI VINGEILVGS TCILTLSIDH 400
    RVIDGYPAAM FMKRLQKILE APSILLLN 428
    Length:428
    Mass (Da):46,397
    Last modified:May 3, 2011 - v1
    Checksum:i98684E7ED24C6699
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002549 Genomic DNA. Translation: ADZ18278.1.
    CP002586 Genomic DNA. Translation: AEB55501.1.
    RefSeqiYP_004422321.1. NC_015470.1.
    YP_005663174.1. NC_017287.1.

    Genome annotation databases

    EnsemblBacteriaiADZ18278; ADZ18278; CPSIT_0516.
    AEB55501; AEB55501; G5O_0512.
    GeneIDi10602218.
    12242934.
    KEGGichb:G5O_0512.
    chp:CPSIT_0516.
    PATRICi47105634. VBIChlPsi52874_0496.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002549 Genomic DNA. Translation: ADZ18278.1 .
    CP002586 Genomic DNA. Translation: AEB55501.1 .
    RefSeqi YP_004422321.1. NC_015470.1.
    YP_005663174.1. NC_017287.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ADZ18278 ; ADZ18278 ; CPSIT_0516 .
    AEB55501 ; AEB55501 ; G5O_0512 .
    GeneIDi 10602218.
    12242934.
    KEGGi chb:G5O_0512.
    chp:CPSIT_0516.
    PATRICi 47105634. VBIChlPsi52874_0496.

    Phylogenomic databases

    KOi K00627.
    OMAi MEMESYE.

    Family and domain databases

    Gene3Di 3.30.559.10. 1 hit.
    4.10.320.10. 1 hit.
    InterProi IPR001078. 2-oxoacid_DH_actylTfrase.
    IPR000089. Biotin_lipoyl.
    IPR023213. CAT-like_dom.
    IPR004167. E3-bd.
    IPR006257. LAT1.
    IPR011053. Single_hybrid_motif.
    [Graphical view ]
    Pfami PF00198. 2-oxoacid_dh. 1 hit.
    PF00364. Biotin_lipoyl. 1 hit.
    PF02817. E3_binding. 1 hit.
    [Graphical view ]
    SUPFAMi SSF47005. SSF47005. 1 hit.
    SSF51230. SSF51230. 1 hit.
    TIGRFAMsi TIGR01349. PDHac_trf_mito. 1 hit.
    PROSITEi PS50968. BIOTINYL_LIPOYL. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Full-length de novo sequence of the Chlamydophila psittaci type strain, 6BC."
      Voigt A., Schofl G., Heidrich A., Sachse K., Saluz H.P.
      J. Bacteriol. 193:2662-2663(2011) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 6BCImported and ATCC VR-125 / 6BC.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 6BCImported and ATCC VR-125 / 6BCImported.
    3. "Full length de novo sequence of the Chlamydophyla psittaci reference strain 6BC."
      Voigt A., Schofl G., Heidrich A., Sachse K., Saluz H.P.
      Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: 6BC.
    4. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: 6BCImported.

    Entry informationi

    Entry nameiF0T408_CHLP6
    AccessioniPrimary (citable) accession number: F0T408
    Entry historyi
    Integrated into UniProtKB/TrEMBL: May 3, 2011
    Last sequence update: May 3, 2011
    Last modified: October 1, 2014
    This is version 21 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3