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F0SXB6

- F0SXB6_SYNGF

UniProt

F0SXB6 - F0SXB6_SYNGF

Protein

Alanine racemase

Gene

Sgly_2703

Organism
Syntrophobotulus glycolicus (strain DSM 8271 / FlGlyR)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 27 (01 Oct 2014)
      Sequence version 1 (03 May 2011)
      Previous versions | rss
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    Functioni

    Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

    Catalytic activityi

    L-alanine = D-alanine.UniRule annotationSAAS annotation

    Cofactori

    Pyridoxal phosphate.UniRule annotationSAAS annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei36 – 361Proton acceptor; specific for D-alanineUniRule annotation
    Binding sitei134 – 1341SubstrateUniRule annotation
    Active sitei262 – 2621Proton acceptor; specific for L-alanineUniRule annotation
    Binding sitei310 – 3101Substrate; via amide nitrogenUniRule annotation

    GO - Molecular functioni

    1. alanine racemase activity Source: UniProtKB-HAMAP
    2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. D-alanine biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    IsomeraseUniRule annotationSAAS annotationImported

    Keywords - Ligandi

    Pyridoxal phosphateUniRule annotationSAAS annotation

    Enzyme and pathway databases

    BioCyciSGLY645991:GHJ4-2766-MONOMER.
    UniPathwayiUPA00042; UER00497.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
    Gene namesi
    Ordered Locus Names:Sgly_2703Imported
    OrganismiSyntrophobotulus glycolicus (strain DSM 8271 / FlGlyR)Imported
    Taxonomic identifieri645991 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesPeptococcaceaeSyntrophobotulus
    ProteomesiUP000007488: Chromosome

    PTM / Processingi

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei36 – 361N6-(pyridoxal phosphate)lysineUniRule annotation

    Structurei

    3D structure databases

    ProteinModelPortaliF0SXB6.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the alanine racemase family.UniRule annotation

    Phylogenomic databases

    KOiK01775.
    OMAiRIGISIY.

    Family and domain databases

    Gene3Di2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPiMF_01201. Ala_racemase.
    InterProiIPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR020622. Ala_racemase_pyridoxalP-BS.
    IPR029066. PLP-binding_barrel.
    [Graphical view]
    PfamiPF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view]
    PRINTSiPR00992. ALARACEMASE.
    SMARTiSM01005. Ala_racemase_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsiTIGR00492. alr. 1 hit.
    PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    F0SXB6-1 [UniParc]FASTAAdd to Basket

    « Hide

    MHGMRPAWAC IDLGALRRNY RRICRQTNSE VMAIVKANAY GHGALEIVRT    50
    LKEEGVRRFG VAILEEALQI REKFPEVTVM LIGPTMPDQA ERIVAEGIIP 100
    EVFRLEQAEA FSLEAEKKGI PAILHIKVDT GMGRIGFQED ALENILKIAQ 150
    LPGIEIEGIY THLATADEID LGFAFTQLKR FDGLYESLKT AGLNIPMRHV 200
    ANSAAILQLR DQEYELCRPG LMLYGQLPMN HWEGENGFEP LMSLKARIVH 250
    LKKIAAGDSV SYGRTFIAQA PTLVATLPLG YADGLRRSLS NNWNVIVKGR 300
    YAPVIGRICM DQTMIDVTGI EGVEIGDEVT ILGSEGKSSL TAAQMAECAG 350
    TISYEILCGI SQRVPRVYID TSQIPK 376
    Length:376
    Mass (Da):41,495
    Last modified:May 3, 2011 - v1
    Checksum:i2EF60465963781AD
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002547 Genomic DNA. Translation: ADY56976.1.
    RefSeqiWP_013625796.1. NC_015172.1.
    YP_004266977.1. NC_015172.1.

    Genome annotation databases

    EnsemblBacteriaiADY56976; ADY56976; Sgly_2703.
    GeneIDi10249921.
    KEGGisgy:Sgly_2703.
    PATRICi47036420. VBISynGly105927_2897.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002547 Genomic DNA. Translation: ADY56976.1 .
    RefSeqi WP_013625796.1. NC_015172.1.
    YP_004266977.1. NC_015172.1.

    3D structure databases

    ProteinModelPortali F0SXB6.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ADY56976 ; ADY56976 ; Sgly_2703 .
    GeneIDi 10249921.
    KEGGi sgy:Sgly_2703.
    PATRICi 47036420. VBISynGly105927_2897.

    Phylogenomic databases

    KOi K01775.
    OMAi RIGISIY.

    Enzyme and pathway databases

    UniPathwayi UPA00042 ; UER00497 .
    BioCyci SGLY645991:GHJ4-2766-MONOMER.

    Family and domain databases

    Gene3Di 2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPi MF_01201. Ala_racemase.
    InterProi IPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR020622. Ala_racemase_pyridoxalP-BS.
    IPR029066. PLP-binding_barrel.
    [Graphical view ]
    Pfami PF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view ]
    PRINTSi PR00992. ALARACEMASE.
    SMARTi SM01005. Ala_racemase_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsi TIGR00492. alr. 1 hit.
    PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: DSM 8271 / FlGlyRImported.

    Entry informationi

    Entry nameiF0SXB6_SYNGF
    AccessioniPrimary (citable) accession number: F0SXB6
    Entry historyi
    Integrated into UniProtKB/TrEMBL: May 3, 2011
    Last sequence update: May 3, 2011
    Last modified: October 1, 2014
    This is version 27 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3