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Protein

Riboflavin biosynthesis protein

Gene

Plabr_2734

Organism
Rubinisphaera brasiliensis (strain ATCC 49424 / DSM 5305 / JCM 21570 / NBRC 103401 / IFAM 1448) (Planctomyces brasiliensis)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + FMN = diphosphate + FAD.UniRule annotation
ATP + riboflavin = ADP + FMN.UniRule annotation

Pathway: FAD biosynthesis

This protein is involved in step 1 of the subpathway that synthesizes FAD from FMN.UniRule annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Riboflavin biosynthesis protein (Plabr_2734)
This subpathway is part of the pathway FAD biosynthesis, which is itself part of Cofactor biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes FAD from FMN, the pathway FAD biosynthesis and in Cofactor biosynthesis.

Pathway: FMN biosynthesis

This protein is involved in step 1 of the subpathway that synthesizes FMN from riboflavin (ATP route).UniRule annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Riboflavin biosynthesis protein (Plabr_2734)
This subpathway is part of the pathway FMN biosynthesis, which is itself part of Cofactor biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes FMN from riboflavin (ATP route), the pathway FMN biosynthesis and in Cofactor biosynthesis.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationImported, NucleotidyltransferaseUniRule annotationImported, Transferase

Keywords - Ligandi

ATP-bindingUniRule annotation, FADUniRule annotation, Flavoprotein, FMNUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciPBRA756272:GH5Q-2768-MONOMER.
UniPathwayiUPA00276; UER00406.
UPA00277; UER00407.

Names & Taxonomyi

Protein namesi
Recommended name:
Riboflavin biosynthesis proteinUniRule annotation (EC:2.7.1.26UniRule annotation, EC:2.7.7.2UniRule annotation)
Gene namesi
Ordered Locus Names:Plabr_2734Imported
OrganismiRubinisphaera brasiliensis (strain ATCC 49424 / DSM 5305 / JCM 21570 / NBRC 103401 / IFAM 1448) (Planctomyces brasiliensis)Imported
Taxonomic identifieri756272 [NCBI]
Taxonomic lineageiBacteriaPlanctomycetesPlanctomycetiaPlanctomycetalesPlanctomycetaceaeRubinisphaera
ProteomesiUP000006860 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi756272.Plabr_2734.

Family & Domainsi

Sequence similaritiesi

Belongs to the ribF family.UniRule annotation

Phylogenomic databases

KOiK11753.

Family and domain databases

Gene3Di2.40.30.30. 1 hit.
3.40.50.620. 1 hit.
InterProiIPR015864. FAD_synthase.
IPR023468. Riboflavin_kinase.
IPR002606. Riboflavin_kinase_bac.
IPR015865. Riboflavin_kinase_bac/euk.
IPR023465. Riboflavin_kinase_domain.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PANTHERiPTHR22749. PTHR22749. 1 hit.
PfamiPF06574. FAD_syn. 1 hit.
PF01687. Flavokinase. 1 hit.
[Graphical view]
PIRSFiPIRSF004491. FAD_Synth. 1 hit.
SMARTiSM00904. Flavokinase. 1 hit.
[Graphical view]
SUPFAMiSSF82114. SSF82114. 1 hit.
TIGRFAMsiTIGR00083. ribF. 1 hit.

Sequencei

Sequence statusi: Complete.

F0SSL8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQILTDISEA EPFRNGAVSI GNFDGVHRGH QAMLSALVEQ ARRLDGPALA
60 70 80 90 100
MTFDPPPVAL ISPAKVPPRL STVERKAELM SKLGVDALLV YPTNREFLSL
110 120 130 140 150
TADDFFQQIV LQQLQAKGMV EGDNFCFGRN RSGTADVLRD YCERSGLELR
160 170 180 190 200
IISPVTAGEK VISSTRIREL IRHGSVSEAI ELLGHPYQLT GKVVSGARRG
210 220 230 240 250
RLIGFPTANL AEVTTLIPSP GVYAGRCEVD GRAIAAAINI GPNPTFAEQE
260 270 280 290 300
HKIEIHLIGH DGDLYGQQLS VELFTECRKI KQFDSAESLR LQLEKDIAQI
310
EQLFQERFGS DAR
Length:313
Mass (Da):34,375
Last modified:May 3, 2011 - v1
Checksum:iD6EF66610B1F4E00
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002546 Genomic DNA. Translation: ADY60334.1.
RefSeqiWP_013629058.1. NC_015174.1.
YP_004270356.1. NC_015174.1.

Genome annotation databases

EnsemblBacteriaiADY60334; ADY60334; Plabr_2734.
KEGGipbs:Plabr_2734.
PATRICi47014664. VBIPlaBra152897_2953.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002546 Genomic DNA. Translation: ADY60334.1.
RefSeqiWP_013629058.1. NC_015174.1.
YP_004270356.1. NC_015174.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi756272.Plabr_2734.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiADY60334; ADY60334; Plabr_2734.
KEGGipbs:Plabr_2734.
PATRICi47014664. VBIPlaBra152897_2953.

Phylogenomic databases

KOiK11753.

Enzyme and pathway databases

UniPathwayiUPA00276; UER00406.
UPA00277; UER00407.
BioCyciPBRA756272:GH5Q-2768-MONOMER.

Family and domain databases

Gene3Di2.40.30.30. 1 hit.
3.40.50.620. 1 hit.
InterProiIPR015864. FAD_synthase.
IPR023468. Riboflavin_kinase.
IPR002606. Riboflavin_kinase_bac.
IPR015865. Riboflavin_kinase_bac/euk.
IPR023465. Riboflavin_kinase_domain.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PANTHERiPTHR22749. PTHR22749. 1 hit.
PfamiPF06574. FAD_syn. 1 hit.
PF01687. Flavokinase. 1 hit.
[Graphical view]
PIRSFiPIRSF004491. FAD_Synth. 1 hit.
SMARTiSM00904. Flavokinase. 1 hit.
[Graphical view]
SUPFAMiSSF82114. SSF82114. 1 hit.
TIGRFAMsiTIGR00083. ribF. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 49424 / DSM 5305 / JCM 21570 / NBRC 103401 / IFAM 1448Imported.

Entry informationi

Entry nameiF0SSL8_RUBBR
AccessioniPrimary (citable) accession number: F0SSL8
Entry historyi
Integrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: May 3, 2011
Last modified: June 24, 2015
This is version 23 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.