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Protein

Xylose isomerase

Gene

xylA

Organism
Rubinisphaera brasiliensis (strain ATCC 49424 / DSM 5305 / JCM 21570 / NBRC 103401 / IFAM 1448) (Planctomyces brasiliensis)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

D-xylopyranose = D-xylulose.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationNote: Binds 2 magnesium ions per subunit.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei100UniRule annotation1
Active sitei103UniRule annotation1
Metal bindingi231Magnesium 1UniRule annotation1
Metal bindingi267Magnesium 1UniRule annotation1
Metal bindingi267Magnesium 2UniRule annotation1
Metal bindingi270Magnesium 2UniRule annotation1
Metal bindingi295Magnesium 1UniRule annotation1
Metal bindingi306Magnesium 2UniRule annotation1
Metal bindingi308Magnesium 2UniRule annotation1
Metal bindingi338Magnesium 1UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomeraseUniRule annotationSAAS annotationImported
Biological processCarbohydrate metabolism, Xylose metabolismUniRule annotationSAAS annotation
LigandMagnesiumUniRule annotation, Metal-bindingUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciPBRA756272:G1GOK-3-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Xylose isomeraseUniRule annotationSAAS annotation (EC:5.3.1.5UniRule annotationSAAS annotation)
Gene namesi
Name:xylAUniRule annotation
Ordered Locus Names:Plabr_0003Imported
OrganismiRubinisphaera brasiliensis (strain ATCC 49424 / DSM 5305 / JCM 21570 / NBRC 103401 / IFAM 1448) (Planctomyces brasiliensis)Imported
Taxonomic identifieri756272 [NCBI]
Taxonomic lineageiBacteriaPlanctomycetesPlanctomycetiaPlanctomycetalesPlanctomycetaceaeRubinisphaera
Proteomesi
  • UP000006860 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Subunit structurei

Homotetramer.UniRule annotationSAAS annotation

Protein-protein interaction databases

STRINGi756272.Plabr_0003

Structurei

3D structure databases

ProteinModelPortaliF0SKL7
SMRiF0SKL7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini86 – 283AP_endonuc_2InterPro annotationAdd BLAST198

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili111 – 131Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the xylose isomerase family.UniRule annotationSAAS annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiENOG4105C93 Bacteria
COG2115 LUCA
KOiK01805
OMAiHTFQHEL
OrthoDBiPOG091H07LC

Family and domain databases

HAMAPiMF_00455 Xylose_isom_A, 1 hit
InterProiView protein in InterPro
IPR036237 Xyl_isomerase-like_sf
IPR013022 Xyl_isomerase-like_TIM-brl
IPR013452 Xylose_isom_bac
IPR001998 Xylose_isomerase
PANTHERiPTHR32176:SF0 PTHR32176:SF0, 1 hit
PfamiView protein in Pfam
PF01261 AP_endonuc_2, 1 hit
PRINTSiPR00688 XYLOSISMRASE
SUPFAMiSSF51658 SSF51658, 1 hit
TIGRFAMsiTIGR02630 xylose_isom_A, 1 hit
PROSITEiView protein in PROSITE
PS51415 XYLOSE_ISOMERASE, 1 hit

Sequencei

Sequence statusi: Complete.

F0SKL7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSYFPDVPTI PFEGPESRNP LAFRYYNPDE MIEGQSMRDL LRFSVCYWHT
60 70 80 90 100
FRGTGGDPFG PGTAVRPWED GTDSVDMAVK RVDVAFEFIS KLGVDFYCFH
110 120 130 140 150
DRDVSPEGSS LKETNGNLDR VVARLKEKQE ETGIKLLWGT ANLFSNPRFM
160 170 180 190 200
HGAATSCNAD VFAYAAAQVK KALEVTKELG GQNYVFWGGR EGYQNLFNTD
210 220 230 240 250
MKRELDHLAR FMHMAKDYAK SIGFDGQFLF EPKPKEPTKH QYDFDVAACV
260 270 280 290 300
NFLRQYGLED TVKMNIETNH ATLAGHSMMH EMEYARIQDM LGSIDANTGD
310 320 330 340 350
LLLGWDTDQF PTDIYLTTQC MLVILKQGGL KPGGINFDAK VRRESFDPTD
360 370 380 390 400
LFYAHIGGMD AFARGAKIAA AIRADGVLDD FVKDRYSSYD SGVGQEIEDG
410 420 430
SANFESLSKY MLDKGEADAN TSGRQEYLEN IINLYV
Length:436
Mass (Da):49,032
Last modified:May 3, 2011 - v1
Checksum:iC7F5DE914979E787
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002546 Genomic DNA Translation: ADY57635.1
RefSeqiWP_013626379.1, NC_015174.1

Genome annotation databases

EnsemblBacteriaiADY57635; ADY57635; Plabr_0003
KEGGipbs:Plabr_0003

Similar proteinsi

Entry informationi

Entry nameiF0SKL7_RUBBR
AccessioniPrimary (citable) accession number: F0SKL7
Entry historyiIntegrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: May 3, 2011
Last modified: May 23, 2018
This is version 51 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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