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F0RPD4 (F0RPD4_DEIPM) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 19. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
D-alanine--D-alanine ligase HAMAP-Rule MF_00047
EC=6.3.2.4 HAMAP-Rule MF_00047
Alternative name(s):
D-Ala-D-Ala ligase HAMAP-Rule MF_00047
D-alanylalanine synthetase HAMAP-Rule MF_00047
Gene names
Name:ddl HAMAP-Rule MF_00047
Ordered Locus Names:Deipr_1328 EMBL ADY26477.1
OrganismDeinococcus proteolyticus (strain ATCC 35074 / DSM 20540 / JCM 6276 / NBRC 101906 / NCIMB 13154 / VKM Ac-1939 / CCM 2703) [Complete proteome] [HAMAP] EMBL ADY26477.1
Taxonomic identifier693977 [NCBI]
Taxonomic lineageBacteria › Deinococcus-Thermus › Deinococci › Deinococcales › Deinococcaceae › Deinococcus ›

Protein attributes

Sequence length360 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Cell wall formation By similarity. HAMAP-Rule MF_00047 SAAS SAAS005905

Catalytic activity

ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine. HAMAP-Rule MF_00047 SAAS SAAS005905

Cofactor

Binds 2 magnesium or manganese ions per subunit By similarity. HAMAP-Rule MF_00047 SAAS SAAS005905

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP-Rule MF_00047 SAAS SAAS005905

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00047 SAAS SAAS005905.

Sequence similarities

Belongs to the D-alanine--D-alanine ligase family. HAMAP-Rule MF_00047

Contains 1 ATP-grasp domain. HAMAP-Rule MF_00047 SAAS SAAS005905

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain147 – 354208ATP-grasp By similarity HAMAP-Rule MF_00047
Nucleotide binding179 – 23456ATP By similarity HAMAP-Rule MF_00047

Sites

Metal binding3071Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding3211Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding3211Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047
Metal binding3231Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047

Sequences

Sequence LengthMass (Da)Tools
F0RPD4 [UniParc].

Last modified May 3, 2011. Version 1.
Checksum: AFF7C8CD00661327

FASTA36038,483
        10         20         30         40         50         60 
MSDLTPAQPQ SPSESPSAPR QPRRRVLLLA GGQSEEHEVS LSSARSVLAA LPQDRFEVTA 

        70         80         90        100        110        120 
VVISKQGRWL PPAETAQALG AGAAESGGEP MLQRVSDTAG YDVVFPLLHG PMGEDGTVQG 

       130        140        150        160        170        180 
LLTLAGLPFV GSGVLGSSVG MDKIMTKRVL EAAGIPQVAW REASRAEWRR DPQGVQSRAA 

       190        200        210        220        230        240 
ELGFPLFVKP ANMGSSVGVS RVTGAGELAE ALELAFGHDR RVIVEAAAGA KPREVEVGIL 

       250        260        270        280        290        300 
GNDDPVASPV GELRFDTDFY DYDTKYTGGR AEMLIPAPLP EGVSERIQEL ALRAYQALDC 

       310        320        330        340        350        360 
AGLSRVDFFY VEETGELLLN EINTMPGFTT TSMYPSLLQA HGLSYPELVT RLIELALEER

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References

[1]"The complete sequence of chromosome of Deinococcus proteolyticus DSM 20540."
US DOE Joint Genome Institute (JGI-PGF)
Lucas S., Copeland A., Lapidus A., Bruce D., Goodwin L., Pitluck S., Kyrpides N., Mavromatis K., Pagani I., Ivanova N., Ovchinnikova G., Zeytun A., Detter J.C., Han C., Land M., Hauser L., Markowitz V., Cheng J.-F. expand/collapse author list , Hugenholtz P., Woyke T., Wu D., Pukall R., Steenblock K., Brambilla E., Klenk H.-P., Eisen J.A.
Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 35074 / DSM 20540 / JCM 6276 / NBRC 101906 / NCIMB 13154 / VKM Ac-1939 / CCM 2703.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP002536 Genomic DNA. Translation: ADY26477.1.
RefSeqYP_004256094.1. NC_015161.1.

3D structure databases

ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADY26477; ADY26477; Deipr_1328.
GeneID10256810.
KEGGdpt:Deipr_1328.
PATRIC46930454. VBIDeiPro159979_1319.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK01921.

Enzyme and pathway databases

UniPathwayUPA00219.

Family and domain databases

Gene3D3.30.1490.20. 1 hit.
3.30.470.20. 2 hits.
3.40.50.20. 1 hit.
HAMAPMF_00047. Dala_Dala_lig.
InterProIPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR000291. D-Ala_lig_Van_CS.
IPR005905. D_ala_D_ala.
IPR011095. Dala_Dala_lig_C.
IPR011127. Dala_Dala_lig_N.
IPR016185. PreATP-grasp_dom.
[Graphical view]
PANTHERPTHR23132. PTHR23132. 1 hit.
PfamPF07478. Dala_Dala_lig_C. 1 hit.
PF01820. Dala_Dala_lig_N. 1 hit.
[Graphical view]
SUPFAMSSF52440. PreATP-grasp-like. 1 hit.
TIGRFAMsTIGR01205. D_ala_D_alaTIGR. 1 hit.
PROSITEPS50975. ATP_GRASP. 1 hit.
PS00843. DALA_DALA_LIGASE_1. 1 hit.
PS00844. DALA_DALA_LIGASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameF0RPD4_DEIPM
AccessionPrimary (citable) accession number: F0RPD4
Entry history
Integrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: May 3, 2011
Last modified: May 1, 2013
This is version 19 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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