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F0R4N1

- F0R4N1_BACSH

UniProt

F0R4N1 - F0R4N1_BACSH

Protein

Isocitrate dehydrogenase [NADP]

Gene

Bacsa_0108

Organism
Bacteroides salanitronis (strain DSM 18170 / JCM 13567 / BL78)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 22 (01 Oct 2014)
      Sequence version 1 (03 May 2011)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    Isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH.UniRule annotation

    Cofactori

    Binds 1 magnesium or manganese ion per subunit.UniRule annotation
    Binds 1 magnesium or manganese ion per subunit By similarity.

    GO - Molecular functioni

    1. isocitrate dehydrogenase (NADP+) activity Source: UniProtKB-EC
    2. magnesium ion binding Source: InterPro
    3. NAD binding Source: InterPro

    GO - Biological processi

    1. glyoxylate cycle Source: UniProtKB-KW
    2. tricarboxylic acid cycle Source: UniProtKB-KW

    Keywords - Molecular functioni

    OxidoreductaseUniRule annotationImported

    Keywords - Biological processi

    Glyoxylate bypassUniRule annotation, Tricarboxylic acid cycleUniRule annotation

    Keywords - Ligandi

    ManganeseUniRule annotation, Metal-bindingUniRule annotation, NADPUniRule annotation

    Enzyme and pathway databases

    BioCyciBSAL667015:GHA0-205-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Isocitrate dehydrogenase [NADP]UniRule annotation (EC:1.1.1.42UniRule annotation)
    Gene namesi
    Ordered Locus Names:Bacsa_0108Imported
    OrganismiBacteroides salanitronis (strain DSM 18170 / JCM 13567 / BL78)Imported
    Taxonomic identifieri667015 [NCBI]
    Taxonomic lineageiBacteriaBacteroidetesBacteroidiaBacteroidalesBacteroidaceaeBacteroides
    ProteomesiUP000007486: Chromosome

    Structurei

    3D structure databases

    ProteinModelPortaliF0R4N1.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the isocitrate and isopropylmalate dehydrogenases family.UniRule annotation

    Phylogenomic databases

    KOiK00031.
    OMAiEYLGWKE.

    Family and domain databases

    Gene3Di3.40.718.10. 1 hit.
    InterProiIPR019818. IsoCit/isopropylmalate_DH_CS.
    IPR001804. Isocitrate/isopropylmalate_DH.
    IPR004439. Isocitrate_DH_NADP_dimer_prok.
    IPR024084. IsoPropMal-DH-like_dom.
    [Graphical view]
    PANTHERiPTHR11835. PTHR11835. 1 hit.
    PfamiPF00180. Iso_dh. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR00183. prok_nadp_idh. 1 hit.
    PROSITEiPS00470. IDH_IMDH. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    F0R4N1-1 [UniParc]FASTAAdd to Basket

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    MSKVQMKDGR LIVPDCVTIP YIEGDGVGAE ITPVCQKIVN EAVRAAYGGK    50
    RSIEWMEVLA GGKAFAQTGE WLPQATLDVF REYLIGIKGP LTTPVGGGIR 100
    SLNVALRQTL DLYVCLRPVR WFKGVVSPLK EPQKVNMHIF RENTEDIYAG 150
    IEWEQGTPEA QKFYTFLHDE MGVSKVRFPE TSSFGVKPVS AEGSKRLVRS 200
    AIRYALQHHQ TSVTLVHKGN IMKFTEGGFK RWGYEVAEQE FPDQTFSMNQ 250
    YNQIKKDLGE ESANAALADA ANTGKVIIKD CIADAFLQNT LLKPEEYAVI 300
    ATLNLNGDYI SDQLAAMVGG IGIAPGANIN YATGHAIFEA THGTAPDIAG 350
    KNIVNPCSML LSSVMMLEHL GWEEAATLIT QALEKLFEAG EATNDLARFM 400
    PNGKPLGTME FGQRVIDALS SN 422
    Length:422
    Mass (Da):46,208
    Last modified:May 3, 2011 - v1
    Checksum:i3CB3D1B347D28F4F
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002530 Genomic DNA. Translation: ADY34721.1.
    RefSeqiWP_013616183.1. NC_015164.1.
    YP_004257194.1. NC_015164.1.

    Genome annotation databases

    EnsemblBacteriaiADY34721; ADY34721; Bacsa_0108.
    GeneIDi10257995.
    KEGGibsa:Bacsa_0108.
    PATRICi46876099. VBIBacSal140776_0116.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002530 Genomic DNA. Translation: ADY34721.1 .
    RefSeqi WP_013616183.1. NC_015164.1.
    YP_004257194.1. NC_015164.1.

    3D structure databases

    ProteinModelPortali F0R4N1.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ADY34721 ; ADY34721 ; Bacsa_0108 .
    GeneIDi 10257995.
    KEGGi bsa:Bacsa_0108.
    PATRICi 46876099. VBIBacSal140776_0116.

    Phylogenomic databases

    KOi K00031.
    OMAi EYLGWKE.

    Enzyme and pathway databases

    BioCyci BSAL667015:GHA0-205-MONOMER.

    Family and domain databases

    Gene3Di 3.40.718.10. 1 hit.
    InterProi IPR019818. IsoCit/isopropylmalate_DH_CS.
    IPR001804. Isocitrate/isopropylmalate_DH.
    IPR004439. Isocitrate_DH_NADP_dimer_prok.
    IPR024084. IsoPropMal-DH-like_dom.
    [Graphical view ]
    PANTHERi PTHR11835. PTHR11835. 1 hit.
    Pfami PF00180. Iso_dh. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR00183. prok_nadp_idh. 1 hit.
    PROSITEi PS00470. IDH_IMDH. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: DSM 18170 / JCM 13567 / BL78Imported.

    Entry informationi

    Entry nameiF0R4N1_BACSH
    AccessioniPrimary (citable) accession number: F0R4N1
    Entry historyi
    Integrated into UniProtKB/TrEMBL: May 3, 2011
    Last sequence update: May 3, 2011
    Last modified: October 1, 2014
    This is version 22 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3