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F0R4N1

- F0R4N1_BACSH

UniProt

F0R4N1 - F0R4N1_BACSH

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Protein
Isocitrate dehydrogenase [NADP]
Gene
Bacsa_0108
Organism
Bacteroides salanitronis (strain DSM 18170 / JCM 13567 / BL78)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

Isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH.

Cofactori

Binds 1 magnesium or manganese ion per subunit By similarity.

GO - Molecular functioni

  1. NAD binding Source: InterPro
  2. isocitrate dehydrogenase (NADP+) activity Source: UniProtKB-EC
  3. magnesium ion binding Source: InterPro
Complete GO annotation...

GO - Biological processi

  1. glyoxylate cycle Source: UniProtKB-KW
  2. tricarboxylic acid cycle Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotationImported

Keywords - Biological processi

Glyoxylate bypassUniRule annotation, Tricarboxylic acid cycleUniRule annotation

Keywords - Ligandi

ManganeseUniRule annotation, Metal-bindingUniRule annotation, NADPUniRule annotation

Enzyme and pathway databases

BioCyciBSAL667015:GHA0-205-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Isocitrate dehydrogenase [NADP]UniRule annotation (EC:1.1.1.42UniRule annotation)
Gene namesi
Ordered Locus Names:Bacsa_0108Imported
OrganismiBacteroides salanitronis (strain DSM 18170 / JCM 13567 / BL78)Imported
Taxonomic identifieri667015 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesBacteroidiaBacteroidalesBacteroidaceaeBacteroides
ProteomesiUP000007486: Chromosome

Structurei

3D structure databases

ProteinModelPortaliF0R4N1.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

KOiK00031.
OMAiEYLGWKE.

Family and domain databases

Gene3Di3.40.718.10. 1 hit.
InterProiIPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR004439. Isocitrate_DH_NADP_dimer_prok.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PANTHERiPTHR11835. PTHR11835. 1 hit.
PfamiPF00180. Iso_dh. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00183. prok_nadp_idh. 1 hit.
PROSITEiPS00470. IDH_IMDH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F0R4N1-1 [UniParc]FASTAAdd to Basket

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MSKVQMKDGR LIVPDCVTIP YIEGDGVGAE ITPVCQKIVN EAVRAAYGGK    50
RSIEWMEVLA GGKAFAQTGE WLPQATLDVF REYLIGIKGP LTTPVGGGIR 100
SLNVALRQTL DLYVCLRPVR WFKGVVSPLK EPQKVNMHIF RENTEDIYAG 150
IEWEQGTPEA QKFYTFLHDE MGVSKVRFPE TSSFGVKPVS AEGSKRLVRS 200
AIRYALQHHQ TSVTLVHKGN IMKFTEGGFK RWGYEVAEQE FPDQTFSMNQ 250
YNQIKKDLGE ESANAALADA ANTGKVIIKD CIADAFLQNT LLKPEEYAVI 300
ATLNLNGDYI SDQLAAMVGG IGIAPGANIN YATGHAIFEA THGTAPDIAG 350
KNIVNPCSML LSSVMMLEHL GWEEAATLIT QALEKLFEAG EATNDLARFM 400
PNGKPLGTME FGQRVIDALS SN 422
Length:422
Mass (Da):46,208
Last modified:May 3, 2011 - v1
Checksum:i3CB3D1B347D28F4F
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002530 Genomic DNA. Translation: ADY34721.1.
RefSeqiWP_013616183.1. NC_015164.1.
YP_004257194.1. NC_015164.1.

Genome annotation databases

EnsemblBacteriaiADY34721; ADY34721; Bacsa_0108.
GeneIDi10257995.
KEGGibsa:Bacsa_0108.
PATRICi46876099. VBIBacSal140776_0116.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002530 Genomic DNA. Translation: ADY34721.1 .
RefSeqi WP_013616183.1. NC_015164.1.
YP_004257194.1. NC_015164.1.

3D structure databases

ProteinModelPortali F0R4N1.
ModBasei Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ADY34721 ; ADY34721 ; Bacsa_0108 .
GeneIDi 10257995.
KEGGi bsa:Bacsa_0108.
PATRICi 46876099. VBIBacSal140776_0116.

Phylogenomic databases

KOi K00031.
OMAi EYLGWKE.

Enzyme and pathway databases

BioCyci BSAL667015:GHA0-205-MONOMER.

Family and domain databases

Gene3Di 3.40.718.10. 1 hit.
InterProi IPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR004439. Isocitrate_DH_NADP_dimer_prok.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view ]
PANTHERi PTHR11835. PTHR11835. 1 hit.
Pfami PF00180. Iso_dh. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR00183. prok_nadp_idh. 1 hit.
PROSITEi PS00470. IDH_IMDH. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 18170 / JCM 13567 / BL78.

Entry informationi

Entry nameiF0R4N1_BACSH
AccessioniPrimary (citable) accession number: F0R4N1
Entry historyi
Integrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: May 3, 2011
Last modified: September 3, 2014
This is version 21 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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