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Protein

Xylose isomerase

Gene

xylA

Organism
Bacteroides salanitronis (strain DSM 18170 / JCM 13567 / BL78)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-xylopyranose = D-xylulose.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationNote: Binds 2 magnesium ions per subunit.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei103 – 1031UniRule annotation
Active sitei106 – 1061UniRule annotation
Metal bindingi234 – 2341Magnesium 1UniRule annotation
Metal bindingi270 – 2701Magnesium 1UniRule annotation
Metal bindingi270 – 2701Magnesium 2UniRule annotation
Metal bindingi273 – 2731Magnesium 2UniRule annotation
Metal bindingi298 – 2981Magnesium 1UniRule annotation
Metal bindingi309 – 3091Magnesium 2UniRule annotation
Metal bindingi311 – 3111Magnesium 2UniRule annotation
Metal bindingi341 – 3411Magnesium 1UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. xylose isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-xylose metabolic process Source: UniProtKB-HAMAP
  2. pentose-phosphate shunt Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotation

Keywords - Biological processi

Carbohydrate metabolism, Pentose shuntUniRule annotation, Xylose metabolismUniRule annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, Metal-bindingUniRule annotation

Enzyme and pathway databases

BioCyciBSAL667015:GHA0-3157-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Xylose isomeraseUniRule annotation (EC:5.3.1.5UniRule annotation)
Gene namesi
Name:xylAUniRule annotation
Ordered Locus Names:Bacsa_2995Imported
OrganismiBacteroides salanitronis (strain DSM 18170 / JCM 13567 / BL78)Imported
Taxonomic identifieri667015 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesBacteroidiaBacteroidalesBacteroidaceaeBacteroides
ProteomesiUP000007486 Componenti: Chromosome

Subcellular locationi

  1. Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Subunit structurei

Homotetramer.UniRule annotationSAAS annotation

Structurei

3D structure databases

ProteinModelPortaliF0R2I6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the xylose isomerase family.UniRule annotation

Phylogenomic databases

KOiK01805.
OMAiHTFQHEL.

Family and domain databases

Gene3Di3.20.20.150. 1 hit.
HAMAPiMF_00455. Xylose_isom_A.
InterProiIPR013022. Xyl_isomerase-like_TIM-brl.
IPR013452. Xylose_isom_bac.
IPR001998. Xylose_isomerase.
[Graphical view]
PfamiPF01261. AP_endonuc_2. 1 hit.
[Graphical view]
PRINTSiPR00688. XYLOSISMRASE.
SUPFAMiSSF51658. SSF51658. 1 hit.
TIGRFAMsiTIGR02630. xylose_isom_A. 1 hit.
PROSITEiPS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F0R2I6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATKEYFPGI GKIKFEGVES KNPLAFRYYD PERVVMGKKM KDWLKFSMAW
60 70 80 90 100
WHTLCAEGGD QFGGGTKQFP WKGNPDKVQA AKDKVDAGFE FMQKVGIEYY
110 120 130 140 150
CFHDVDLCDE ADTIEEYEAN LKEVVAYLKQ KQAETGIKLL WGTANVFGHA
160 170 180 190 200
RYMNGAATNP DFDVVARAAV QIKNAIDATI ELGGTNYVFW GGREGYMSLL
210 220 230 240 250
NTDQKREKEH LAQMLTIARD YARAKGFTGT FLVEPKPMEP TKHQYDVDTE
260 270 280 290 300
TVIGFLKAHN LDKDFKVNIE VNHATLAGHT FEHELCVAVD NGMLGSIDAN
310 320 330 340 350
RGDYQNGWDT DQFPIDNYEL TQAMIQVIRN GGFGNGGTNF DAKTRRNSTD
360 370 380 390 400
LEDIFIAHIA GMDVMARALL SAAKMLEESP YKKMLADRYA SFDAGKGKEF
410 420 430
EEGKLTLEDV VAYAKTVGEP KQTSGKQELY EAILNMYC
Length:438
Mass (Da):49,167
Last modified:May 3, 2011 - v1
Checksum:i8FBC1B8D4DFA5377
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002530 Genomic DNA. Translation: ADY37524.1.
RefSeqiWP_013618897.1. NC_015164.1.
YP_004259997.1. NC_015164.1.

Genome annotation databases

EnsemblBacteriaiADY37524; ADY37524; Bacsa_2995.
KEGGibsa:Bacsa_2995.
PATRICi46882293. VBIBacSal140776_3130.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002530 Genomic DNA. Translation: ADY37524.1.
RefSeqiWP_013618897.1. NC_015164.1.
YP_004259997.1. NC_015164.1.

3D structure databases

ProteinModelPortaliF0R2I6.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiADY37524; ADY37524; Bacsa_2995.
KEGGibsa:Bacsa_2995.
PATRICi46882293. VBIBacSal140776_3130.

Phylogenomic databases

KOiK01805.
OMAiHTFQHEL.

Enzyme and pathway databases

BioCyciBSAL667015:GHA0-3157-MONOMER.

Family and domain databases

Gene3Di3.20.20.150. 1 hit.
HAMAPiMF_00455. Xylose_isom_A.
InterProiIPR013022. Xyl_isomerase-like_TIM-brl.
IPR013452. Xylose_isom_bac.
IPR001998. Xylose_isomerase.
[Graphical view]
PfamiPF01261. AP_endonuc_2. 1 hit.
[Graphical view]
PRINTSiPR00688. XYLOSISMRASE.
SUPFAMiSSF51658. SSF51658. 1 hit.
TIGRFAMsiTIGR02630. xylose_isom_A. 1 hit.
PROSITEiPS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 18170 / JCM 13567 / BL78Imported.

Entry informationi

Entry nameiF0R2I6_BACSH
AccessioniPrimary (citable) accession number: F0R2I6
Entry historyi
Integrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: May 3, 2011
Last modified: April 29, 2015
This is version 31 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.