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F0Q8E2

- F0Q8E2_ACIAP

UniProt

F0Q8E2 - F0Q8E2_ACIAP

Protein

Homoserine kinase

Gene

thrB

Organism
Acidovorax avenae (strain ATCC 19860 / DSM 7227 / JCM 20985 / NCPPB 1011)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 21 (01 Oct 2014)
      Sequence version 1 (03 May 2011)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + L-homoserine = ADP + O-phospho-L-homoserine.UniRule annotationSAAS annotation

    Pathwayi

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. homoserine kinase activity Source: UniProtKB-EC

    GO - Biological processi

    1. threonine biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    KinaseUniRule annotationSAAS annotationImported, Transferase

    Keywords - Biological processi

    Amino-acid biosynthesis, Threonine biosynthesisUniRule annotationSAAS annotation

    Keywords - Ligandi

    ATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciAAVE643561:GHRD-3280-MONOMER.
    UniPathwayiUPA00050; UER00064.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Homoserine kinaseUniRule annotation (EC:2.7.1.39UniRule annotation)
    Short name:
    HKUniRule annotation
    Short name:
    HSKUniRule annotation
    Gene namesi
    Name:thrBUniRule annotation
    Ordered Locus Names:Acav_3238Imported
    OrganismiAcidovorax avenae (strain ATCC 19860 / DSM 7227 / JCM 20985 / NCPPB 1011)Imported
    Taxonomic identifieri643561 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesComamonadaceaeAcidovorax
    ProteomesiUP000002482: Chromosome

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the pseudomonas-type ThrB family.UniRule annotation

    Phylogenomic databases

    KOiK02204.
    OMAiNAWCFEP.

    Family and domain databases

    HAMAPiMF_00301. Homoser_kinase_2.
    InterProiIPR002575. Aminoglycoside_PTrfase.
    IPR005280. Homoserine_kinase_ThrB.
    IPR011009. Kinase-like_dom.
    [Graphical view]
    PfamiPF01636. APH. 1 hit.
    [Graphical view]
    SUPFAMiSSF56112. SSF56112. 1 hit.
    TIGRFAMsiTIGR00938. thrB_alt. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    F0Q8E2-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAVFTEVSKK EARDLLRRLQ LGTLESLRGI EGGIENTNYF LTSDQGEYVL    50
    TLFERLTAEQ LPFYLHLMKH LAQAGMPVPD PRGDRHGNIL HTVAGKPAAV 100
    VNKLPGRSQL APEPVHCAAV GGMLARMHLA GRDYERRQPN LRGLAWWNET 150
    VPVVLPHIGE SQRTLLRSEL AYQNHVAASA GYAALPRGPV HADLFRDNAM 200
    FDGEVLTGFF DFYFAGVDTW LFDLAVCLND WCIDWPTGLH APGRATAMLD 250
    AYQAVRPLSA DERALLPAML RAGALRFWIS RLWDFHLPRE ASLLTPHDPT 300
    HFERVLRGRI AQPLHVRAGG GFAE 324
    Length:324
    Mass (Da):36,138
    Last modified:May 3, 2011 - v1
    Checksum:i480027D2CBA07CF9
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002521 Genomic DNA. Translation: ADX47140.1.
    RefSeqiYP_004235707.1. NC_015138.1.

    Genome annotation databases

    EnsemblBacteriaiADX47140; ADX47140; Acav_3238.
    GeneIDi10308181.
    KEGGiaaa:Acav_3238.
    PATRICi46841387. VBIAciAve68977_3318.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002521 Genomic DNA. Translation: ADX47140.1 .
    RefSeqi YP_004235707.1. NC_015138.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ADX47140 ; ADX47140 ; Acav_3238 .
    GeneIDi 10308181.
    KEGGi aaa:Acav_3238.
    PATRICi 46841387. VBIAciAve68977_3318.

    Phylogenomic databases

    KOi K02204.
    OMAi NAWCFEP.

    Enzyme and pathway databases

    UniPathwayi UPA00050 ; UER00064 .
    BioCyci AAVE643561:GHRD-3280-MONOMER.

    Family and domain databases

    HAMAPi MF_00301. Homoser_kinase_2.
    InterProi IPR002575. Aminoglycoside_PTrfase.
    IPR005280. Homoserine_kinase_ThrB.
    IPR011009. Kinase-like_dom.
    [Graphical view ]
    Pfami PF01636. APH. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56112. SSF56112. 1 hit.
    TIGRFAMsi TIGR00938. thrB_alt. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Complete sequence of Acidovorax avenae subsp. avenae ATCC 19860."
      Lucas S., Copeland A., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S., Chertkov O., Held B., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Ivanova N., Ovchinnikova G., Pagani I., Gordon S., Woyke T.
      Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 19860 / DSM 7227 / JCM 20985 / NCPPB 1011Imported.

    Entry informationi

    Entry nameiF0Q8E2_ACIAP
    AccessioniPrimary (citable) accession number: F0Q8E2
    Entry historyi
    Integrated into UniProtKB/TrEMBL: May 3, 2011
    Last sequence update: May 3, 2011
    Last modified: October 1, 2014
    This is version 21 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3