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F0Q8E2

- F0Q8E2_ACIAP

UniProt

F0Q8E2 - F0Q8E2_ACIAP

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Protein
Homoserine kinase
Gene
thrB, Acav_3238
Organism
Acidovorax avenae (strain ATCC 19860 / DSM 7227 / JCM 20985 / NCPPB 1011)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-homoserine = ADP + O-phospho-L-homoserine.UniRule annotationSAAS annotations

Pathwayi

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. homoserine kinase activity Source: UniProtKB-EC
Complete GO annotation...

GO - Biological processi

  1. threonine biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationSAAS annotationsImported, Transferase

Keywords - Biological processi

Amino-acid biosynthesis, Threonine biosynthesisUniRule annotationSAAS annotations

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotations, Nucleotide-binding

Enzyme and pathway databases

BioCyciAAVE643561:GHRD-3280-MONOMER.
UniPathwayiUPA00050; UER00064.

Names & Taxonomyi

Protein namesi
Recommended name:
Homoserine kinaseUniRule annotation (EC:2.7.1.39UniRule annotation)
Short name:
HKUniRule annotation
Short name:
HSKUniRule annotation
Gene namesi
Name:thrBUniRule annotation
Ordered Locus Names:Acav_3238Imported
OrganismiAcidovorax avenae (strain ATCC 19860 / DSM 7227 / JCM 20985 / NCPPB 1011)Imported
Taxonomic identifieri643561 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesComamonadaceaeAcidovorax
ProteomesiUP000002482: Chromosome

Family & Domainsi

Sequence similaritiesi

Belongs to the pseudomonas-type ThrB family.UniRule annotation

Phylogenomic databases

KOiK02204.
OMAiNAWCFEP.

Family and domain databases

HAMAPiMF_00301. Homoser_kinase_2.
InterProiIPR002575. Aminoglycoside_PTrfase.
IPR005280. Homoserine_kinase_ThrB.
IPR011009. Kinase-like_dom.
[Graphical view]
PfamiPF01636. APH. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
TIGRFAMsiTIGR00938. thrB_alt. 1 hit.

Sequencei

Sequence statusi: Complete.

F0Q8E2-1 [UniParc]FASTAAdd to Basket

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MAVFTEVSKK EARDLLRRLQ LGTLESLRGI EGGIENTNYF LTSDQGEYVL    50
TLFERLTAEQ LPFYLHLMKH LAQAGMPVPD PRGDRHGNIL HTVAGKPAAV 100
VNKLPGRSQL APEPVHCAAV GGMLARMHLA GRDYERRQPN LRGLAWWNET 150
VPVVLPHIGE SQRTLLRSEL AYQNHVAASA GYAALPRGPV HADLFRDNAM 200
FDGEVLTGFF DFYFAGVDTW LFDLAVCLND WCIDWPTGLH APGRATAMLD 250
AYQAVRPLSA DERALLPAML RAGALRFWIS RLWDFHLPRE ASLLTPHDPT 300
HFERVLRGRI AQPLHVRAGG GFAE 324
Length:324
Mass (Da):36,138
Last modified:May 3, 2011 - v1
Checksum:i480027D2CBA07CF9
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002521 Genomic DNA. Translation: ADX47140.1.
RefSeqiYP_004235707.1. NC_015138.1.

Genome annotation databases

EnsemblBacteriaiADX47140; ADX47140; Acav_3238.
GeneIDi10308181.
KEGGiaaa:Acav_3238.
PATRICi46841387. VBIAciAve68977_3318.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002521 Genomic DNA. Translation: ADX47140.1 .
RefSeqi YP_004235707.1. NC_015138.1.

3D structure databases

ModBasei Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ADX47140 ; ADX47140 ; Acav_3238 .
GeneIDi 10308181.
KEGGi aaa:Acav_3238.
PATRICi 46841387. VBIAciAve68977_3318.

Phylogenomic databases

KOi K02204.
OMAi NAWCFEP.

Enzyme and pathway databases

UniPathwayi UPA00050 ; UER00064 .
BioCyci AAVE643561:GHRD-3280-MONOMER.

Family and domain databases

HAMAPi MF_00301. Homoser_kinase_2.
InterProi IPR002575. Aminoglycoside_PTrfase.
IPR005280. Homoserine_kinase_ThrB.
IPR011009. Kinase-like_dom.
[Graphical view ]
Pfami PF01636. APH. 1 hit.
[Graphical view ]
SUPFAMi SSF56112. SSF56112. 1 hit.
TIGRFAMsi TIGR00938. thrB_alt. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Complete sequence of Acidovorax avenae subsp. avenae ATCC 19860."
    Lucas S., Copeland A., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S., Chertkov O., Held B., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Ivanova N., Ovchinnikova G., Pagani I., Gordon S., Woyke T.
    Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 19860 / DSM 7227 / JCM 20985 / NCPPB 1011.

Entry informationi

Entry nameiF0Q8E2_ACIAP
AccessioniPrimary (citable) accession number: F0Q8E2
Entry historyi
Integrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: May 3, 2011
Last modified: May 14, 2014
This is version 20 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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