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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Acidovorax avenae (strain ATCC 19860 / DSM 7227 / JCM 20985 / NCPPB 1011)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei165UniRule annotation1
Active sitei607UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyaseUniRule annotationSAAS annotationImported
Biological processCarbon dioxide fixationUniRule annotationSAAS annotation
LigandMagnesiumUniRule annotationSAAS annotation, PyruvateImported

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
Ordered Locus Names:Acav_3162Imported
OrganismiAcidovorax avenae (strain ATCC 19860 / DSM 7227 / JCM 20985 / NCPPB 1011)Imported
Taxonomic identifieri643561 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesComamonadaceaeAcidovorax
Proteomesi
  • UP000002482 Componenti: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotationSAAS annotation

Phylogenomic databases

KOiK01595.
OMAiPWVFGWT.
OrthoDBiPOG091H040O.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1. 1 hit.
InterProiView protein in InterPro
IPR021135. PEP_COase.
IPR022805. PEP_COase_bac/pln-type.
IPR018129. PEP_COase_Lys_AS.
IPR033129. PEPCASE_His_AS.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
PfamiView protein in Pfam
PF00311. PEPcase. 1 hit.
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiView protein in PROSITE
PS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.

Sequencei

Sequence statusi: Complete.

F0Q7J1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNATPSRKTD PVSEPQAAPS PGRRADKDQP LIQDIRLLGR ILGDVIREQE
60 70 80 90 100
GVAAYDLVEQ VRKLSVAFRR DADQEADKAL KKLLKGLSGD QTVSVIRAFT
110 120 130 140 150
YFSHLANLAE DRHHIRRRTV HERAGSTQEG SIEVALARLR WAGIAPRTVA
160 170 180 190 200
QTLARSYVSP VLTAHPTEVQ RKSILDAERD IAELLAERDE IQARGLFYKS
210 220 230 240 250
ARDALTPREL AANEARLRAR VAQLWQTRLL RYSKLTVADE IENALSYYES
260 270 280 290 300
TFLREIPRLY EDLERALGSQ PVASFLRMGQ WIGGDRDGNP NVSAETLALA
310 320 330 340 350
LRRQAEVALR HYLTEVHYLG GELSLSARLV QVSPEMEQLA ERSPDTSEHR
360 370 380 390 400
QDEPYRRALT GIYARLAATL RELTGGEAAR HAVAPQNPYG DASEFLADLR
410 420 430 440 450
VIEASLRSHR GAPLAAQRLH PLVRAVEVFG FHLATVDLRQ SSDQHERVVA
460 470 480 490 500
ELLATARIET DYAALPEDAR QALLVRLLCD ARPLRVVGAE YSEHTRGEIA
510 520 530 540 550
IFETARRMRD RYGAQAIRHY IISHTETVSD LLEVLLLQKE VGLMHGTLDG
560 570 580 590 600
ADARADLIVV PLFETIGDLR NAQPIMRALY EVPGFAAMVQ RGGAEQDIML
610 620 630 640 650
GYSDSNKDGG IFTSNWELYR AEIALVELFD VLEARHRIRL RLFHGRGGTV
660 670 680 690 700
GRGGGPSYQA ILAQPPGTVR GQIRLTEQGE VIASKYANPE IGRRNLETLV
710 720 730 740 750
AATLEATLLQ PTKPATKAFH EAAAELSQAS MAAYRALVYD TPGFADYFFN
760 770 780 790 800
STPIREIAEL NIGSRPASRK PSQKIEDLRA IPWGFSWGQC RLTLPGWYGF
810 820 830 840 850
GSAVEAFVKA ADEDPKARMA LLQKMYRQWP FFRTLLSNMD MVLAKSDLAL
860 870 880 890 900
ASRYSELVAD ARLRRKVFGA IEAEWQRTVD ALARITGDRQ RLAHNTALAR
910 920 930 940 950
SIRHRFPYID PLHHLQVELV RRWRAGEGSE RVQTGIHICI NGIAAGLRNT

G
Length:951
Mass (Da):106,175
Last modified:May 3, 2011 - v1
Checksum:i143134BDE63FE681
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002521 Genomic DNA. Translation: ADX47064.1.
RefSeqiWP_013595553.1. NC_015138.1.

Genome annotation databases

EnsemblBacteriaiADX47064; ADX47064; Acav_3162.
KEGGiaaa:Acav_3162.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002521 Genomic DNA. Translation: ADX47064.1.
RefSeqiWP_013595553.1. NC_015138.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiADX47064; ADX47064; Acav_3162.
KEGGiaaa:Acav_3162.

Phylogenomic databases

KOiK01595.
OMAiPWVFGWT.
OrthoDBiPOG091H040O.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1. 1 hit.
InterProiView protein in InterPro
IPR021135. PEP_COase.
IPR022805. PEP_COase_bac/pln-type.
IPR018129. PEP_COase_Lys_AS.
IPR033129. PEPCASE_His_AS.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
PfamiView protein in Pfam
PF00311. PEPcase. 1 hit.
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiView protein in PROSITE
PS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiF0Q7J1_ACIAP
AccessioniPrimary (citable) accession number: F0Q7J1
Entry historyiIntegrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: May 3, 2011
Last modified: June 7, 2017
This is version 43 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.