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Protein

Elongation factor Tu

Gene

tuf

Organism
Acidovorax avenae (strain ATCC 19860 / DSM 7227 / JCM 20985 / NCPPB 1011)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi19 – 268GTPUniRule annotation
Nucleotide bindingi81 – 855GTPUniRule annotation
Nucleotide bindingi136 – 1394GTPUniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Elongation factorUniRule annotationImported

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

GTP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciAAVE643561:GHRD-404-MONOMER.
AAVE643561:GHRD-4511-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Elongation factor TuUniRule annotation
Short name:
EF-TuUniRule annotation
Gene namesi
Name:tufUniRule annotation
Ordered Locus Names:Acav_0404Imported, Acav_4455Imported
OrganismiAcidovorax avenae (strain ATCC 19860 / DSM 7227 / JCM 20985 / NCPPB 1011)Imported
Taxonomic identifieri643561 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesComamonadaceaeAcidovorax
ProteomesiUP000002482 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotation

PTM / Processingi

Proteomic databases

PRIDEiF0Q4F6.

Interactioni

Subunit structurei

Monomer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliF0Q4F6.
SMRiF0Q4F6. Positions 2-396.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.UniRule annotation

Phylogenomic databases

KOiK02358.
OMAiDEGGRHN.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_00118_B. EF_Tu_B.
InterProiIPR000795. EF_GTP-bd_dom.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004161. Transl_elong_EFTu/EF1A_2.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
[Graphical view]
PfamiPF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
[Graphical view]
PRINTSiPR00315. ELONGATNFCT.
SUPFAMiSSF50447. SSF50447. 1 hit.
SSF50465. SSF50465. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEiPS00301. EFACTOR_GTP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F0Q4F6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKGKFERTK PHVNVGTIGH VDHGKTTLTA AIATVLSAKF GGEAKKYDEI
60 70 80 90 100
DAAPEEKARG ITINTAHVEY ETANRHYAHV DCPGHADYVK NMITGAAQMD
110 120 130 140 150
GAILVCSAAD GPMPQTREHI LLARQVGVPY IIVFLNKCDM VDDEELLELV
160 170 180 190 200
EMEVRELLDK YDFPGDDTPI VRGSAKLALE GDKGPLGEQA IDKLAEALDT
210 220 230 240 250
YIPTPERAVD GAFLMPVEDV FSISGRGTVV TGRVERGIIK VGEEIEIVGI
260 270 280 290 300
RDTQKTTCTG VEMFRKLLDQ GQAGDNVGLL LRGTKREDVE RGQVLCKPGS
310 320 330 340 350
IKPHTHFTAE VYVLSKDEGG RHTPFFNNYR PQFYFRTTDV TGAIELPADK
360 370 380 390
EMVMPGDNVS ITVKLINPIA MEEGLRFAIR EGGRTVGAGV VAKIIA
Length:396
Mass (Da):43,128
Last modified:May 3, 2011 - v1
Checksum:i5C34207F34B14637
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002521 Genomic DNA. Translation: ADX44327.1.
CP002521 Genomic DNA. Translation: ADX48338.1.
RefSeqiWP_011793521.1. NC_015138.1.
YP_004232894.1. NC_015138.1.
YP_004236905.1. NC_015138.1.

Genome annotation databases

EnsemblBacteriaiADX44327; ADX44327; Acav_0404.
ADX48338; ADX48338; Acav_4455.
KEGGiaaa:Acav_0404.
aaa:Acav_4455.
PATRICi46835382. VBIAciAve68977_0410.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002521 Genomic DNA. Translation: ADX44327.1.
CP002521 Genomic DNA. Translation: ADX48338.1.
RefSeqiWP_011793521.1. NC_015138.1.
YP_004232894.1. NC_015138.1.
YP_004236905.1. NC_015138.1.

3D structure databases

ProteinModelPortaliF0Q4F6.
SMRiF0Q4F6. Positions 2-396.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiF0Q4F6.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiADX44327; ADX44327; Acav_0404.
ADX48338; ADX48338; Acav_4455.
KEGGiaaa:Acav_0404.
aaa:Acav_4455.
PATRICi46835382. VBIAciAve68977_0410.

Phylogenomic databases

KOiK02358.
OMAiDEGGRHN.

Enzyme and pathway databases

BioCyciAAVE643561:GHRD-404-MONOMER.
AAVE643561:GHRD-4511-MONOMER.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_00118_B. EF_Tu_B.
InterProiIPR000795. EF_GTP-bd_dom.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004161. Transl_elong_EFTu/EF1A_2.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
[Graphical view]
PfamiPF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
[Graphical view]
PRINTSiPR00315. ELONGATNFCT.
SUPFAMiSSF50447. SSF50447. 1 hit.
SSF50465. SSF50465. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEiPS00301. EFACTOR_GTP. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Complete sequence of Acidovorax avenae subsp. avenae ATCC 19860."
    US DOE Joint Genome Institute
    Lucas S., Copeland A., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S., Chertkov O., Held B., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Ivanova N., Ovchinnikova G., Pagani I., Gordon S., Woyke T.
    Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: ATCC 19860Imported.
  2. "Complete sequence of Acidovorax avenae subsp. avenae ATCC 19860."
    Lucas S., Copeland A., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S., Chertkov O., Held B., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Ivanova N., Ovchinnikova G., Pagani I., Gordon S., Woyke T.
    Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 19860 / DSM 7227 / JCM 20985 / NCPPB 1011Imported.

Entry informationi

Entry nameiF0Q4F6_ACIAP
AccessioniPrimary (citable) accession number: F0Q4F6
Entry historyi
Integrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: May 3, 2011
Last modified: May 27, 2015
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.