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F0P2Y3

- F0P2Y3_WEEVC

UniProt

F0P2Y3 - F0P2Y3_WEEVC

Protein
Submitted name:

Isocitrate dehydrogenase, NADP-dependent

Gene

Weevi_1186

Organism
Weeksella virosa (strain ATCC 43766 / DSM 16922 / JCM 21250 / NBRC 16016 / NCTC 11634 / CL345/78)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi
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    • History
      Entry version 24 (01 Oct 2014)
      Sequence version 1 (03 May 2011)
      Previous versions | rss
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    Functioni

    Cofactori

    Binds 1 magnesium or manganese ion per subunit.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei145 – 1451SubstrateUniRule annotation
    Sitei255 – 2551Critical for catalysis
    Metal bindingi348 – 3481Magnesium or manganeseUniRule annotation
    Sitei418 – 4181Critical for catalysisUniRule annotation
    Binding sitei545 – 5451SubstrateUniRule annotation
    Metal bindingi546 – 5461Magnesium or manganeseUniRule annotation
    Metal bindingi550 – 5501Magnesium or manganeseUniRule annotation

    GO - Molecular functioni

    1. isocitrate dehydrogenase (NADP+) activity Source: UniProtKB-EC
    2. metal ion binding Source: UniProtKB-KW

    GO - Biological processi

    1. tricarboxylic acid cycle Source: InterPro

    Keywords - Molecular functioni

    OxidoreductaseImported

    Keywords - Ligandi

    MagnesiumUniRule annotation, Metal-bindingUniRule annotation

    Enzyme and pathway databases

    BioCyciWVIR865938:GHXX-1227-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Isocitrate dehydrogenase, NADP-dependentImported (EC:1.1.1.42Imported)
    Gene namesi
    Ordered Locus Names:Weevi_1186Imported
    OrganismiWeeksella virosa (strain ATCC 43766 / DSM 16922 / JCM 21250 / NBRC 16016 / NCTC 11634 / CL345/78)Imported
    Taxonomic identifieri865938 [NCBI]
    Taxonomic lineageiBacteriaBacteroidetesFlavobacteriiaFlavobacterialesFlavobacteriaceaeWeeksella
    ProteomesiUP000008641: Chromosome

    Structurei

    3D structure databases

    ProteinModelPortaliF0P2Y3.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni132 – 1398Substrate bindingUniRule annotation

    Phylogenomic databases

    KOiK00031.

    Family and domain databases

    Gene3Di3.40.718.10. 3 hits.
    InterProiIPR004436. Isocitrate_DH_NADP_mono.
    IPR024084. IsoPropMal-DH-like_dom.
    [Graphical view]
    PfamiPF03971. IDH. 1 hit.
    [Graphical view]
    PIRSFiPIRSF009407. IDH_monmr. 1 hit.
    TIGRFAMsiTIGR00178. monomer_idh. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    F0P2Y3-1 [UniParc]FASTAAdd to Basket

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    MSKSKIFYTL TDEAPMLATH SFLPIVKAFT KSADVEIAVP DISLAGRILA    50
    NFSSYLKDDQ KVADALIELG ELATKPEANI IKLPNISASI PQLEGAIAEL 100
    QAKGYAVPNY PAEPKNEEEK AIKAQYAKVL GSAVNPVLRE GNSDRRAPKA 150
    VKNYAKANPH RMGDWTKDSQ TDVAHMDHGD FYGTETSTTI ENATKFRIVF 200
    KSIDGKEEVL KDFAPLQAGE VIDSSVMNIN ALKEFVKSAI GEAEKRNVLL 250
    SAHLKATMMK ISDPIIFGAI VETYFSDVFA KYAETFKSLD ISPNNGLAGL 300
    FEKIKGNPQE EEIKADIAKT IENGPRLAMV NSDKGITNFH VPSDVIVDAS 350
    MAALVRGGGK MWNKDGNEED TIAIIPDRSY AGFYQSVIDD MKANGKLDPT 400
    TMGSVPNVGL MAQKAEEYGS HDKTFQAQAN GTIEVQSEDG AVLLSQKVEK 450
    GDIFRMCQTK DAPIQDWVKL AVNRSRLSET PAIFWLDKER AHDREIIKKV 500
    EKYLGDHDTK GLDIRIMDVK DAMTETLKRA REGKDTISVS GNVLRDYLTD 550
    LFPILELGTS AKMLSIVPLM NGGGLFETGA GGSAPKHVQQ FVEEGYLRWD 600
    SLGEFLALQA SLEHLAQTQN NPKAQILADA LDQANAEFLS TNKSPGRKLG 650
    TIDNRGSHFY LAMYWAKALA EQTKDEELAK LFAPIAAKMK EQEDKINEEL 700
    IGAQGKPQDI GGYYKTDFSK TDAAMRPSAT LNEIIQSI 738
    Length:738
    Mass (Da):80,971
    Last modified:May 3, 2011 - v1
    Checksum:i65383B3A4088D40B
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002455 Genomic DNA. Translation: ADX67895.1.
    RefSeqiWP_013598285.1. NC_015144.1.
    YP_004238473.1. NC_015144.1.

    Genome annotation databases

    EnsemblBacteriaiADX67895; ADX67895; Weevi_1186.
    GeneIDi10282418.
    KEGGiwvi:Weevi_1186.
    PATRICi47059768. VBIWeeVir165365_1203.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002455 Genomic DNA. Translation: ADX67895.1 .
    RefSeqi WP_013598285.1. NC_015144.1.
    YP_004238473.1. NC_015144.1.

    3D structure databases

    ProteinModelPortali F0P2Y3.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ADX67895 ; ADX67895 ; Weevi_1186 .
    GeneIDi 10282418.
    KEGGi wvi:Weevi_1186.
    PATRICi 47059768. VBIWeeVir165365_1203.

    Phylogenomic databases

    KOi K00031.

    Enzyme and pathway databases

    BioCyci WVIR865938:GHXX-1227-MONOMER.

    Family and domain databases

    Gene3Di 3.40.718.10. 3 hits.
    InterProi IPR004436. Isocitrate_DH_NADP_mono.
    IPR024084. IsoPropMal-DH-like_dom.
    [Graphical view ]
    Pfami PF03971. IDH. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF009407. IDH_monmr. 1 hit.
    TIGRFAMsi TIGR00178. monomer_idh. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 43766 / DSM 16922 / JCM 21250 / NBRC 16016 / NCTC 11634 / CL345/78Imported.

    Entry informationi

    Entry nameiF0P2Y3_WEEVC
    AccessioniPrimary (citable) accession number: F0P2Y3
    Entry historyi
    Integrated into UniProtKB/TrEMBL: May 3, 2011
    Last sequence update: May 3, 2011
    Last modified: October 1, 2014
    This is version 24 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3