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F0NZ99 (F0NZ99_WEEVC) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 22. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
D-alanine--D-alanine ligase HAMAP-Rule MF_00047

EC=6.3.2.4 HAMAP-Rule MF_00047
Alternative name(s):
D-Ala-D-Ala ligase HAMAP-Rule MF_00047
D-alanylalanine synthetase HAMAP-Rule MF_00047
Gene names
Name:ddl HAMAP-Rule MF_00047
Ordered Locus Names:Weevi_0509 EMBL ADX67228.1
OrganismWeeksella virosa (strain ATCC 43766 / DSM 16922 / JCM 21250 / NBRC 16016 / NCTC 11634 / CL345/78) [Complete proteome] [HAMAP] EMBL ADX67228.1
Taxonomic identifier865938 [NCBI]
Taxonomic lineageBacteriaBacteroidetesFlavobacteriiaFlavobacterialesFlavobacteriaceaeWeeksella

Protein attributes

Sequence length329 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Cell wall formation By similarity. HAMAP-Rule MF_00047 SAAS SAAS005905

Catalytic activity

ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine. HAMAP-Rule MF_00047 SAAS SAAS005905

Cofactor

Binds 2 magnesium or manganese ions per subunit By similarity. HAMAP-Rule MF_00047 SAAS SAAS005905

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP-Rule MF_00047 SAAS SAAS005905

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00047 SAAS SAAS005905.

Sequence similarities

Belongs to the D-alanine--D-alanine ligase family. HAMAP-Rule MF_00047

Contains 1 ATP-grasp domain. HAMAP-Rule MF_00047

Contains ATP-grasp domain. SAAS SAAS005905

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain119 – 318200ATP-grasp By similarity HAMAP-Rule MF_00047
Nucleotide binding147 – 20256ATP By similarity HAMAP-Rule MF_00047

Sites

Metal binding2731Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding2851Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding2851Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047
Metal binding2871Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047

Sequences

Sequence LengthMass (Da)Tools
F0NZ99 [UniParc].

Last modified May 3, 2011. Version 1.
Checksum: 667CFA2BCFE583C6

FASTA32936,853
        10         20         30         40         50         60 
MLKVAVVAGG YSDESVISLK SCELIYQNIN TEKYEPIRVR ILKDAWYAEI DGEKYPINKA 

        70         80         90        100        110        120 
DFSFERNGKK EKFDLVYNTI HGTPGEDGYL QAYFDLIGLP YNGCDSYQSA LTFNKKDCIA 

       130        140        150        160        170        180 
VLSKYGIPHA KSVYLYQGEK VEPKKIVEQL GLPCFVKPNK SGSSLGISKV HREEDIPKAL 

       190        200        210        220        230        240 
ELAFAEDKEV LIEAFLDGLE VSVGVLKYKG KTTVLGITEI VSDNEFFDYE AKYDGKSQEI 

       250        260        270        280        290        300 
TPARISQETE ESVKAIATKV YDSLNMNGFS RAEYIIVDNQ PYLLEINTLP GMSPASIFPQ 

       310        320 
QAAYAGISLQ ELVQNELDFA LNRPKPWNV 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP002455 Genomic DNA. Translation: ADX67228.1.
RefSeqYP_004237806.1. NC_015144.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADX67228; ADX67228; Weevi_0509.
GeneID10281712.
KEGGwvi:Weevi_0509.
PATRIC47058325. VBIWeeVir165365_0511.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK01921.

Enzyme and pathway databases

BioCycWVIR865938:GHXX-521-MONOMER.
UniPathwayUPA00219.

Family and domain databases

Gene3D3.30.1490.20. 1 hit.
3.30.470.20. 2 hits.
3.40.50.20. 1 hit.
HAMAPMF_00047. Dala_Dala_lig.
InterProIPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR000291. D-Ala_lig_Van_CS.
IPR005905. D_ala_D_ala.
IPR011095. Dala_Dala_lig_C.
IPR011127. Dala_Dala_lig_N.
IPR016185. PreATP-grasp_dom.
[Graphical view]
PANTHERPTHR23132. PTHR23132. 1 hit.
PfamPF07478. Dala_Dala_lig_C. 1 hit.
PF01820. Dala_Dala_lig_N. 1 hit.
[Graphical view]
SUPFAMSSF52440. SSF52440. 1 hit.
TIGRFAMsTIGR01205. D_ala_D_alaTIGR. 1 hit.
PROSITEPS50975. ATP_GRASP. 1 hit.
PS00843. DALA_DALA_LIGASE_1. 1 hit.
PS00844. DALA_DALA_LIGASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameF0NZ99_WEEVC
AccessionPrimary (citable) accession number: F0NZ99
Entry history
Integrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: May 3, 2011
Last modified: February 19, 2014
This is version 22 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)