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F0NMR2

- F0NMR2_SULIH

UniProt

F0NMR2 - F0NMR2_SULIH

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Protein
Phosphoenolpyruvate carboxylase
Gene
ppcA, SiH_0069
Organism
Sulfolobus islandicus (strain HVE10/4)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle By similarity.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotation

Cofactori

Magnesium By similarity.UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotation

Keywords - Ligandi

MagnesiumUniRule annotation, PyruvateImported

Enzyme and pathway databases

BioCyciSISL930943:GLLW-72-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcAUniRule annotation
Ordered Locus Names:SiH_0069Imported
OrganismiSulfolobus islandicus (strain HVE10/4)Imported
Taxonomic identifieri930943 [NCBI]
Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiSulfolobalesSulfolobaceaeSulfolobus
ProteomesiUP000006395: Chromosome

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 2 family.UniRule annotation

Phylogenomic databases

KOiK01595.
OMAiDEYMPDY.

Family and domain databases

HAMAPiMF_01904. PEPcase_type2.
InterProiIPR007566. PEP_COase_arc-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF14010. PEPcase_2. 1 hit.
[Graphical view]
PIRSFiPIRSF006677. UCP006677. 1 hit.
SUPFAMiSSF51621. SSF51621. 1 hit.
TIGRFAMsiTIGR02751. PEPCase_arch. 1 hit.

Sequencei

Sequence statusi: Complete.

F0NMR2-1 [UniParc]FASTAAdd to Basket

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MRIIPRTMST QHPDNAKVPE WAKSEVIEGE DEVKEAFLAY SMYGVHEVMW    50
DAEGKDVDTH VVRKLLSNYP DYFREHILGK DVFLTYRLPN PKVEGADRKV 100
FAETMESIPI TYDLAEKFYG NGITVPVFEV ILPMTTSNLE IISVARYYEK 150
AVANEDELEL YDGVKVKDLV GEIYPKVIEV IPLVEDRDSL QNIDNIVEGY 200
YKVIKPKYMR VFLARSDPAM NYGMITAVLS VKIALSELYK LSESLNFEIY 250
PIIGVGSLPF RGHLSPENYE KVLEEYKGVY TYTIQSAFKY DYDYDKVKSA 300
ISSINNSRIG PAKILEKYEE DVLRKITILY TERYQPIIES LANAINDVSM 350
LLPRRRARKL HIGLFGYSRS AGKVSLPRAI SFVGSLYSIG IPPELIGISS 400
LSNLDEKEWD IFKQNYVNFK HDLQTAARFF NWESFELIKD IWKISEDTIA 450
KIKEDIDYAE SVIGIKLGDI DYDSRKHILM SSLFLLSFKE KILQESKKYL 500
YEMALIRRSL G 511
Length:511
Mass (Da):58,839
Last modified:May 3, 2011 - v1
Checksum:iF2174B790D5B4C60
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002426 Genomic DNA. Translation: ADX81441.1.
RefSeqiWP_014511791.1. NC_017275.1.
YP_005644655.1. NC_017275.1.

Genome annotation databases

EnsemblBacteriaiADX81441; ADX81441; SiH_0069.
GeneIDi12414089.
KEGGisih:SiH_0069.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002426 Genomic DNA. Translation: ADX81441.1 .
RefSeqi WP_014511791.1. NC_017275.1.
YP_005644655.1. NC_017275.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ADX81441 ; ADX81441 ; SiH_0069 .
GeneIDi 12414089.
KEGGi sih:SiH_0069.

Phylogenomic databases

KOi K01595.
OMAi DEYMPDY.

Enzyme and pathway databases

BioCyci SISL930943:GLLW-72-MONOMER.

Family and domain databases

HAMAPi MF_01904. PEPcase_type2.
InterProi IPR007566. PEP_COase_arc-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view ]
Pfami PF14010. PEPcase_2. 1 hit.
[Graphical view ]
PIRSFi PIRSF006677. UCP006677. 1 hit.
SUPFAMi SSF51621. SSF51621. 1 hit.
TIGRFAMsi TIGR02751. PEPCase_arch. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Genome analyses of icelandic strains of Sulfolobus islandicus, model organisms for genetic and virus-host interaction studies."
    Guo L., Brugger K., Liu C., Shah S.A., Zheng H., Zhu Y., Wang S., Lillestol R.K., Chen L., Frank J., Prangishvili D., Paulin L., She Q., Huang L., Garrett R.A.
    J. Bacteriol. 193:1672-1680(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: HVE10/4Imported.

Entry informationi

Entry nameiF0NMR2_SULIH
AccessioniPrimary (citable) accession number: F0NMR2
Entry historyi
Integrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: May 3, 2011
Last modified: September 3, 2014
This is version 19 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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