F0N7V4 (F0N7V4_NEIMN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Elongation factor Tu HAMAP-Rule MF_00118
Short name=EF-Tu HAMAP-Rule MF_00118

Gene names

Name:	tuf HAMAP-Rule MF_00118
Ordered Locus Names:	NMBNZ0533_0127 EMBL ADZ02613.1, NMBNZ0533_0142 EMBL ADZ02627.1

Organism

Neisseria meningitidis serogroup B (strain NZ-05/33) [Complete proteome] [HAMAP]

Taxonomic identifier

935589 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Betaproteobacteria › Neisseriales › Neisseriaceae › Neisseria › Neisseria meningitidis

Protein attributes

Sequence length	394 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis By similarity. RuleBase RU000325 HAMAP-Rule MF_00118
Subunit structure	Monomer By similarity. HAMAP-Rule MF_00118
Subcellular location	Cytoplasm By similarity HAMAP-Rule MF_00118.
Sequence similarities	Belongs to the GTP-binding elongation factor family. EF-Tu/EF-1A subfamily. RuleBase RU000325 HAMAP-Rule MF_00118

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm HAMAP-Rule MF_00118
Ligand	GTP-binding RuleBase RU000323 HAMAP-Rule MF_00118 Nucleotide-binding
Molecular function	Elongation factor RuleBase RU000325 HAMAP-Rule MF_00118 EMBL ADZ02613.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	GTP catabolic process Inferred from electronic annotation. Source: GOC
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	GTP binding Inferred from electronic annotation. Source: HAMAP GTPase activity Inferred from electronic annotation. Source: InterPro translation elongation factor activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Regions
	Nucleotide binding	19 – 26	8	GTP By similarity HAMAP-Rule MF_00118
	Nucleotide binding	81 – 85	5	GTP By similarity HAMAP-Rule MF_00118
	Nucleotide binding	136 – 139	4	GTP By similarity HAMAP-Rule MF_00118

Sequences

	Sequence		Length	Mass (Da)
	F0N7V4 [UniParc]. Last modified May 3, 2011. Version 1. Checksum: 0C571C3D20CBE944	FASTA	394	42,909
	10 20 30 40 50 60 MAKEKFERSK PHVNVGTIGH VDHGKTTLTA ALTTILAKKF GGAAKAYDQI DNAPEEKARG 70 80 90 100 110 120 ITINTSHVEY ETETRHYAHV DCPGHADYVK NMITGAAQMD GAILVCSAAD GPMPQTREHI 130 140 150 160 170 180 LLARQVGVPY IIVFMNKCDM VDDAELLELV EMEIRDLLSS YDFPGDDCPI VQGSALKALE 190 200 210 220 230 240 GDAAYEEKIF ELAAALDSYI PTPERAVDKP FLLPIEDVFS ISGRGTVVTG RVERGIIHVG 250 260 270 280 290 300 DEIEIVGLKE TQKTTCTGVE MFRKLLDEGQ AGDNVGVLLR GTKREDVERG QVLAKPGTIT 310 320 330 340 350 360 PHTKFKAEVY VLSKEEGGRH TPFFANYRPQ FYFRTTDVTG AVTLEEGVEM VMPGENVTIT 370 380 390 VELIAPIAME EGLRFAIREG GRTVGAGVVS SVIA

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	Hostetler J., Khouri H., Fedorova N., Radune D., Neuendorf B., Ishmael N., Forberger H., Dimitrov G., Szczypinski B., Puiu D., Annavarapu S., Shetty J., Viswanathan L., Busam D., Beeson K., McIntosh T., Daugherty S.C., Durkin A.S. , Huot Creasy H., Creasy T., Dunning Hotopp J., Riley D., Angiuoli S., Budroni S., Siena E., Seib K., Serruto D., Nofroni C., Comanducci M., Covacci A., Pizza M., Rappuoli R., Moxon R., Tettelin H., Medini D. Submitted (DEC-2010) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: NZ-05/33 EMBL ADZ02613.1.
[2]	"Neisseria meningitidis is structured in clades associated with restriction modification systems that modulate homologous recombination." Budroni S., Siena E., Dunning Hotopp J.C., Seib K.L., Serruto D., Nofroni C., Comanducci M., Riley D.R., Daugherty S.C., Angiuoli S.V., Covacci A., Pizza M., Rappuoli R., Moxon E.R., Tettelin H., Medini D. Proc. Natl. Acad. Sci. U.S.A. 108:4494-4499(2011) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: NZ-05/33 EMBL ADZ02613.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP002424 Genomic DNA. Translation: ADZ02613.1. CP002424 Genomic DNA. Translation: ADZ02627.1.
RefSeq	YP_005902784.1. NC_017518.1. YP_005902798.1. NC_017518.1.
3D structure databases
SMR	F0N7V4. Positions 2-394.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ADZ02613; ADZ02613; NMBNZ0533_0127. ADZ02627; ADZ02627; NMBNZ0533_0142.
GeneID	12493478. 12493493.
KEGG	nmz:NMBNZ0533_0127. nmz:NMBNZ0533_0142.
PATRIC	47172253. VBINeiMen179262_0154.
Organism-specific databases
CMR	Search...
Phylogenomic databases
KO	K02358.
Enzyme and pathway databases
BioCyc	NMEN935589:GLHU-127-MONOMER. NMEN935589:GLHU-142-MONOMER.
Family and domain databases
HAMAP	MF_00118_B. EF_Tu_B.
InterPro	IPR000795. EF_GTP-bd_dom. IPR027417. P-loop_NTPase. IPR005225. Small_GTP-bd_dom. IPR009001. Transl_elong_EF1A/Init_IF2_C. IPR004161. Transl_elong_EFTu/EF1A_2. IPR004541. Transl_elong_EFTu/EF1A_bac/org. IPR004160. Transl_elong_EFTu/EF1A_C. IPR009000. Transl_elong_init/rib_B-barrel. [Graphical view]
Pfam	PF00009. GTP_EFTU. 1 hit. PF03144. GTP_EFTU_D2. 1 hit. PF03143. GTP_EFTU_D3. 1 hit. [Graphical view]
PRINTS	PR00315. ELONGATNFCT.
SUPFAM	SSF50465. Elong_init_C. 1 hit. SSF52540. SSF52540. 1 hit. SSF50447. Translat_factor. 1 hit.
TIGRFAMs	TIGR00485. EF-Tu. 1 hit. TIGR00231. small_GTP. 1 hit.
PROSITE	PS00301. EFACTOR_GTP. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

F0N7V4_NEIMN

Accession

Primary (citable) accession number: F0N7V4

Entry history

Integrated into UniProtKB/TrEMBL:	May 3, 2011
Last sequence update:	May 3, 2011
Last modified:	May 29, 2013
This is version 17 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)