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F0N2W4

- F0N2W4_NEIMO

UniProt

F0N2W4 - F0N2W4_NEIMO

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Protein

Elongation factor Tu

Gene
tuf, NMBM04240196_0130
Organism
Neisseria meningitidis serogroup B (strain M04-240196)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis By similarity.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi19 – 268GTP By similarityUniRule annotation
Nucleotide bindingi81 – 855GTP By similarityUniRule annotation
Nucleotide bindingi136 – 1394GTP By similarityUniRule annotation

GO - Molecular functioni

  1. GTPase activity Source: InterPro
  2. GTP binding Source: UniProtKB-HAMAP
  3. translation elongation factor activity Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Elongation factorUniRule annotationImported

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

GTP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciNMEN935593:GLHT-130-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Elongation factor TuUniRule annotation
Short name:
EF-TuUniRule annotation
Gene namesi
Name:tufUniRule annotation
Ordered Locus Names:NMBM04240196_0130Imported
OrganismiNeisseria meningitidis serogroup B (strain M04-240196)Imported
Taxonomic identifieri935593 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaNeisserialesNeisseriaceaeNeisseria
ProteomesiUP000007481: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotation

PTM / Processingi

Proteomic databases

PRIDEiF0N2W4.

Interactioni

Subunit structurei

Monomer By similarity.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliF0N2W4.
SMRiF0N2W4. Positions 2-394.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

KOiK02358.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_00118_B. EF_Tu_B.
InterProiIPR000795. EF_GTP-bd_dom.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004161. Transl_elong_EFTu/EF1A_2.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
[Graphical view]
PfamiPF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
[Graphical view]
PRINTSiPR00315. ELONGATNFCT.
SUPFAMiSSF50447. SSF50447. 1 hit.
SSF50465. SSF50465. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEiPS00301. EFACTOR_GTP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F0N2W4-1 [UniParc]FASTAAdd to Basket

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MAKEKFERSK PHVNVGTIGH VDHGKTTLTA ALTTILAKKF GGAAKAYDQI    50
DNAPEEKARG ITINTSHVEY ETETRHYAHV DCPGHADYVK NMITGAAQMD 100
GAILVCSAAD GPMPQTREHI LLARQVGVPY IIVFMNKCDM VDDAELLELV 150
EMEIRDLLSS YDFPGDDCPI VQGSALKALE GDAAYEEKIF ELAAALDSYI 200
PTPERAVDKP FLLPIEDVFS ISGRGTVVTG RVERGIIHVG DEIEIVGLKE 250
TQKTTCTGVE MFRKLLDEGQ AGDNVGVLLR GTKREDVERG QVLAKPGTIT 300
PHTKFKAEVY VLSKEEGGRH TPFFANYRPQ FYFRTTDVTG AVTLEEGVEM 350
VMPGENVTIT VELIAPIAME EGLRFAIREG GRTVGAGVVS SVIA 394
Length:394
Mass (Da):42,909
Last modified:May 3, 2011 - v1
Checksum:i0C571C3D20CBE944
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002423 Genomic DNA. Translation: ADZ00670.1.
RefSeqiYP_005896909.1. NC_017515.1.

Genome annotation databases

EnsemblBacteriaiADZ00670; ADZ00670; NMBM04240196_0130.
GeneIDi12487193.
KEGGinmq:NMBM04240196_0130.
PATRICi47166390. VBINeiMen179694_0156.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002423 Genomic DNA. Translation: ADZ00670.1 .
RefSeqi YP_005896909.1. NC_017515.1.

3D structure databases

ProteinModelPortali F0N2W4.
SMRi F0N2W4. Positions 2-394.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi F0N2W4.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ADZ00670 ; ADZ00670 ; NMBM04240196_0130 .
GeneIDi 12487193.
KEGGi nmq:NMBM04240196_0130.
PATRICi 47166390. VBINeiMen179694_0156.

Phylogenomic databases

KOi K02358.

Enzyme and pathway databases

BioCyci NMEN935593:GLHT-130-MONOMER.

Family and domain databases

Gene3Di 3.40.50.300. 1 hit.
HAMAPi MF_00118_B. EF_Tu_B.
InterProi IPR000795. EF_GTP-bd_dom.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004161. Transl_elong_EFTu/EF1A_2.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
[Graphical view ]
Pfami PF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
[Graphical view ]
PRINTSi PR00315. ELONGATNFCT.
SUPFAMi SSF50447. SSF50447. 1 hit.
SSF50465. SSF50465. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsi TIGR00485. EF-Tu. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEi PS00301. EFACTOR_GTP. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Neisseria meningitidis is structured in clades associated with restriction modification systems that modulate homologous recombination."
    Budroni S., Siena E., Dunning Hotopp J.C., Seib K.L., Serruto D., Nofroni C., Comanducci M., Riley D.R., Daugherty S.C., Angiuoli S.V., Covacci A., Pizza M., Rappuoli R., Moxon E.R., Tettelin H., Medini D.
    Proc. Natl. Acad. Sci. U.S.A. 108:4494-4499(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: M04-240196Imported.

Entry informationi

Entry nameiF0N2W4_NEIMO
AccessioniPrimary (citable) accession number: F0N2W4
Entry historyi
Integrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: May 3, 2011
Last modified: June 11, 2014
This is version 18 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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