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F0N0E1

- F0N0E1_NEIMO

UniProt

F0N0E1 - F0N0E1_NEIMO

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Protein
Submitted name:

Ferric enterobactin receptor

Gene

fetA

Organism
Neisseria meningitidis serogroup B (strain M04-240196)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi110 – 1101IronImported
Metal bindingi111 – 1111Iron; via tele nitrogenImported
Metal bindingi325 – 3251IronImported
Metal bindingi551 – 5511Iron; via tele nitrogenImported

GO - Molecular functioni

  1. iron ion binding Source: InterPro
  2. receptor activity Source: InterPro
  3. siderophore transmembrane transporter activity Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

ReceptorImported

Keywords - Ligandi

IronImported, Metal-bindingImported

Enzyme and pathway databases

BioCyciNMEN935593:GLHT-1924-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Ferric enterobactin receptorImported
Gene namesi
Name:fetAImported
Ordered Locus Names:NMBM04240196_1925Imported
OrganismiNeisseria meningitidis serogroup B (strain M04-240196)Imported
Taxonomic identifieri935593 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaNeisserialesNeisseriaceaeNeisseria
ProteomesiUP000007481: Chromosome

Subcellular locationi

Cell outer membrane UniRule annotation

GO - Cellular componenti

  1. cell outer membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cell outer membraneSAAS annotation, Membrane

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4AIQX-ray2.60A23-723[»]
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the TonB-dependent receptor family.UniRule annotation

Keywords - Domaini

TonB boxUniRule annotationSAAS annotation

Phylogenomic databases

KOiK16087.

Family and domain databases

Gene3Di2.170.130.10. 1 hit.
2.40.170.20. 1 hit.
InterProiIPR017690. OM_insertion_C_omp85_target.
IPR012910. Plug.
IPR000531. TonB-dep_rcpt_b-brl.
IPR010917. TonB_rcpt_CS.
IPR010105. TonB_sidphr_rcpt.
[Graphical view]
PfamiPF07715. Plug. 1 hit.
PF00593. TonB_dep_Rec. 1 hit.
[Graphical view]
TIGRFAMsiTIGR03304. OMP85_target. 2 hits.
TIGR01783. TonB-siderophor. 1 hit.
PROSITEiPS01156. TONB_DEPENDENT_REC_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F0N0E1-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MNTPLFRLSL LSLTLAAGFA HAAENNAKVV LDTVTVKGDR QGSKIRTNIV
60 70 80 90 100
TLQQKDESTA TDMRELLKEE PSIDFGGGNG TSQFLTLRGM GQNSVDIKVD
110 120 130 140 150
NAYSDSQILY HQGRFIVDPA LVKVVSVQKG AGSASAGIGA TNGAIIAKTV
160 170 180 190 200
DAQDLLKGLD KNWGVRLNSG FASNEGVSYG ASVFGKEGNF DGLFSYNRND
210 220 230 240 250
EKEYEAGKGF RNFNGGKTVP YSALDKRSYL AKIGTTFGDG DHRIVLSHMK
260 270 280 290 300
DQHRGIRTVR EEFTVGDASS RTNITRQAPS YRETTQSNTN LAYTGKDLGF
310 320 330 340 350
VEKLDANAYV LEKKRYSADD KDNGYAGNVV GPNHTRITTR GMNFNFDSRL
360 370 380 390 400
AEQTLLKYGI NYRHQEIKPQ AFLNGEFEIS GKKKDPKDPK KEIDKTDEEK
410 420 430 440 450
AKDKKDMDLV HSYKLSNPTK TDTGAYIEAI HEIDGFTLTG GLRYDRFKVK
460 470 480 490 500
THDGKTVSSS NLNPSFGVIW QPHEHWSFSS SHNYASRSPR LYDALQTHGK
510 520 530 540 550
RGIISIADGT KAERARNTEI GFNYNDGTFA ANGSYFWQTI KDALANPQNR
560 570 580 590 600
HVSAAVREAV NAGYIKNHGY ELGASYRTGG LTAKVGVSHS KPRFYDTHPK
610 620 630 640 650
KLLSANPEFG AQVGRTWTAS LAYRFQNPNL EIGWRGRYVQ KAVGSILVAG
660 670 680 690 700
QKDRNGKLEN VVRKGFGVND VFANWKPLGK DTLNVNLSVN NVFNTFYYPH
710 720
SQRWTNTLPG VGRDVRLGVN YKF
Length:723
Mass (Da):80,013
Last modified:May 3, 2011 - v1
Checksum:i1B16D1B8AE0E6339
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002423 Genomic DNA. Translation: ADZ02346.1.
RefSeqiYP_005898585.1. NC_017515.1.

Genome annotation databases

EnsemblBacteriaiADZ02346; ADZ02346; NMBM04240196_1925.
GeneIDi12488988.
KEGGinmq:NMBM04240196_1925.
PATRICi47171466. VBINeiMen179694_2574.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002423 Genomic DNA. Translation: ADZ02346.1 .
RefSeqi YP_005898585.1. NC_017515.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
4AIQ X-ray 2.60 A 23-723 [» ]
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ADZ02346 ; ADZ02346 ; NMBM04240196_1925 .
GeneIDi 12488988.
KEGGi nmq:NMBM04240196_1925.
PATRICi 47171466. VBINeiMen179694_2574.

Phylogenomic databases

KOi K16087.

Enzyme and pathway databases

BioCyci NMEN935593:GLHT-1924-MONOMER.

Family and domain databases

Gene3Di 2.170.130.10. 1 hit.
2.40.170.20. 1 hit.
InterProi IPR017690. OM_insertion_C_omp85_target.
IPR012910. Plug.
IPR000531. TonB-dep_rcpt_b-brl.
IPR010917. TonB_rcpt_CS.
IPR010105. TonB_sidphr_rcpt.
[Graphical view ]
Pfami PF07715. Plug. 1 hit.
PF00593. TonB_dep_Rec. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR03304. OMP85_target. 2 hits.
TIGR01783. TonB-siderophor. 1 hit.
PROSITEi PS01156. TONB_DEPENDENT_REC_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Neisseria meningitidis is structured in clades associated with restriction modification systems that modulate homologous recombination."
    Budroni S., Siena E., Hotopp J.C., Seib K.L., Serruto D., Nofroni C., Comanducci M., Riley D.R., Daugherty S.C., Angiuoli S.V., Covacci A., Pizza M., Rappuoli R., Moxon E.R., Tettelin H., Medini D.
    Proc. Natl. Acad. Sci. U.S.A. 108:4494-4499(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: M04-240196Imported.
  2. "Use of a molecular decoy to segregate transport from antigenicity in the FrpB iron transporter from Neisseria meningitidis."
    Saleem M., Prince S.M., Rigby S.E., Imran M., Patel H., Chan H., Sanders H., Maiden M.C., Feavers I.M., Derrick J.P.
    PLoS ONE 8:e56746-e56746(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.60 ANGSTROMS) OF 23-723 IN COMPLEX WITH IRON.

Entry informationi

Entry nameiF0N0E1_NEIMO
AccessioniPrimary (citable) accession number: F0N0E1
Entry historyi
Integrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: May 3, 2011
Last modified: October 29, 2014
This is version 23 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureImported, Complete proteomeImported

External Data

Dasty 3