Skip Header

Contribute Send feedback
Read comments (?) or add your own

F0MSN8 (F0MSN8_NEIMM) Unreviewed, UniProtKB/TrEMBL

Last modified May 29, 2013. Version 16. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Histidine--tRNA ligase HAMAP-Rule MF_00127
EC=6.1.1.21 HAMAP-Rule MF_00127
Alternative name(s):
Histidyl-tRNA synthetase HAMAP-Rule MF_00127
Gene names
Name:hisS HAMAP-Rule MF_00127 EMBL ADY97813.1
Ordered Locus Names:NMBM01240149_1243 EMBL ADY97813.1
OrganismNeisseria meningitidis serogroup B (strain M01-240149) [Complete proteome] [HAMAP]
Taxonomic identifier935591 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Neisseriales › Neisseriaceae › Neisseria ›

Protein attributes

Sequence length431 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-histidine + tRNA(His) = AMP + diphosphate + L-histidyl-tRNA(His). HAMAP-Rule MF_00127 SAAS SAAS015807

Subunit structure

Homodimer By similarity. HAMAP-Rule MF_00127

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00127.

Sequence similarities

Belongs to the class-II aminoacyl-tRNA synthetase family. HAMAP-Rule MF_00127 RuleBase RU003746

Sequences

Sequence LengthMass (Da)Tools
F0MSN8 [UniParc].

Last modified May 3, 2011. Version 1.
Checksum: 255AE6196749D2D9

FASTA43148,618
        10         20         30         40         50         60 
MAQKIQSVKG MNDLLPVEQK DFKLTAAFWQ VFEDTVNRWT RAYGYQQIRT PIVEQTGLFV 

        70         80         90        100        110        120 
RSIGEETDVV GKEMYTFSDS NDSLSLSLRP EGTASCLRAV VEHNLLYNSP QKLWYMGPMF 

       130        140        150        160        170        180 
RRERPQKGRY RQFHQVGIEA LGFEGPDIDA EIIAMSADLW EKLGIREYLT LEINSLGNRE 

       190        200        210        220        230        240 
ERAAHRAALV EYLTRYEDKL DEDSKRRLKT NPLRVLDTKN PDLQEICNAA PRLVDYLGEA 

       250        260        270        280        290        300 
SQNHYARFKA MLDGLGIQYI ENPRLVRGLD YYNQTVFEWT TDKLGAQATV CGGGRYDGLI 

       310        320        330        340        350        360 
EELGGKPAPS IGFAMGIERL LLLVSEYGSL EVNAAPDVYA MHQGERADLQ VMKYAQALRA 

       370        380        390        400        410        420 
QGFNVMQHSG YQSLKAQMKK ADNSGARFAL IVAQDELANG TVTLKDMNGA HGQQTVAAED 

       430 
LTHTLQQWKN A

« Hide

References

[1]"Neisseria meningitidis is structured in clades associated with restriction modification systems that modulate homologous recombination."
Budroni S., Siena E., Dunning Hotopp J.C., Seib K.L., Serruto D., Nofroni C., Comanducci M., Riley D.R., Daugherty S.C., Angiuoli S.V., Covacci A., Pizza M., Rappuoli R., Moxon E.R., Tettelin H., Medini D.
Proc. Natl. Acad. Sci. U.S.A. 108:4494-4499(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: M01-240149 EMBL ADY97813.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP002421 Genomic DNA. Translation: ADY97813.1.
RefSeqYP_005896024.1. NC_017514.1.

3D structure databases

ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADY97813; ADY97813; NMBM01240149_1243.
GeneID12412923.
KEGGnmm:NMBM01240149_1243.
PATRIC47157840. VBINeiMen175098_1701.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK01892.
OMACGGGNFK.

Enzyme and pathway databases

BioCycNMEN935591:GLHR-1242-MONOMER.

Family and domain databases

Gene3D3.40.50.800. 1 hit.
HAMAPMF_00127. His_tRNA_synth.
InterProIPR006195. aa-tRNA-synth_II.
IPR004154. Anticodon-bd.
IPR015807. His-tRNA-ligase.
IPR004516. HisRS/HisZ.
[Graphical view]
PANTHERPTHR11476. PTHR11476. 1 hit.
PfamPF03129. HGTP_anticodon. 1 hit.
[Graphical view]
PIRSFPIRSF001549. His-tRNA_synth. 1 hit.
SUPFAMSSF52954. Anticodon_bd. 1 hit.
TIGRFAMsTIGR00442. hisS. 1 hit.
PROSITEPS50862. AA_TRNA_LIGASE_II. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameF0MSN8_NEIMM
AccessionPrimary (citable) accession number: F0MSN8
Entry history
Integrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: May 3, 2011
Last modified: May 29, 2013
This is version 16 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info