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F0M945 (F0M945_ARTPP) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 18. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Probable DNA ligase HAMAP-Rule MF_00407

EC=6.5.1.1 HAMAP-Rule MF_00407
Alternative name(s):
Polydeoxyribonucleotide synthase [ATP] HAMAP-Rule MF_00407
Gene names
Name:lig HAMAP-Rule MF_00407
Ordered Locus Names:Asphe3_27260 EMBL ADX73845.1
OrganismArthrobacter phenanthrenivorans (strain DSM 18606 / JCM 16027 / LMG 23796 / Sphe3) [Complete proteome] [HAMAP] EMBL ADX73845.1
Taxonomic identifier930171 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesMicrococcineaeMicrococcaceaeArthrobacter

Protein attributes

Sequence length507 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair By similarity. HAMAP-Rule MF_00407

Catalytic activity

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m). HAMAP-Rule MF_00407

Cofactor

Divalent metal cations By similarity. HAMAP-Rule MF_00407

Sequence similarities

Belongs to the ATP-dependent DNA ligase family. RuleBase RU004196 HAMAP-Rule MF_00407

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site2111N6-AMP-lysine intermediate By similarity HAMAP-Rule MF_00407
Binding site2091ATP By similarity HAMAP-Rule MF_00407
Binding site2161ATP By similarity HAMAP-Rule MF_00407
Binding site2311ATP By similarity HAMAP-Rule MF_00407
Binding site2601ATP By similarity HAMAP-Rule MF_00407
Binding site2951ATP By similarity HAMAP-Rule MF_00407
Binding site3661ATP By similarity HAMAP-Rule MF_00407
Binding site3721ATP By similarity HAMAP-Rule MF_00407

Sequences

Sequence LengthMass (Da)Tools
F0M945 [UniParc].

Last modified May 3, 2011. Version 1.
Checksum: D2A727A1DBF63FF1

FASTA50753,440
        10         20         30         40         50         60 
MLLDELVNTT QAVASTRSRL AKVDALAGLL KRLEPAEIAT AVGLLIARPR QGRVGVGWSG 

        70         80         90        100        110        120 
MKAAMGEPAA EPSLTVAEVD AALDRLLGTA GTGSAAERAG ILRTLTGAAT EREQAFIAGV 

       130        140        150        160        170        180 
LLGELRTGAL EGVLTDAVAR AAGRPADAVR RAAMLSGDLG GTALLALTGT AEQLDAVGLV 

       190        200        210        220        230        240 
VGRPVQPMLA ATASSVSDAL GTTGEASVEY KLDGARIQVH RAGDDVRVYT RTLAEVTHRL 

       250        260        270        280        290        300 
PEVVEVVRGL PVREVILDGE TLALDEDGGP RPFQETMSRF GADAARDTLL HPWFFDVLHI 

       310        320        330        340        350        360 
DGRDLLDEPL ATRIGVLESI APGHRIPGEV TADVAVAEKV SREALAAGHE GVVVKAIGSA 

       370        380        390        400        410        420 
YAAGRRGSNW VKVKPVLTYD LVVLACEWGS GRRTGLLSNL HLGALDPLGE FGAPGGYVMV 

       430        440        450        460        470        480 
GKTFKGLTDA LLKWQTARFQ ELEVRRTAGT VWVEPVTVVE IAIDGVQQSP RYPGGIALRF 

       490        500 
ARVKRYRDDK TAAEADTIQT LRALLRP 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP002379 Genomic DNA. Translation: ADX73845.1.
RefSeqYP_004241979.1. NC_015145.1.

3D structure databases

ProteinModelPortalF0M945.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADX73845; ADX73845; Asphe3_27260.
GeneID10286093.
KEGGapn:Asphe3_27260.
PATRIC46863824. VBIArtPhe178037_2701.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK01971.

Enzyme and pathway databases

BioCycAPHE930171:GJHZ-2718-MONOMER.

Family and domain databases

Gene3D1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
HAMAPMF_00407. DNA_ligase.
InterProIPR022865. DNA_ligae_ATP-dep_bac/arc.
IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SUPFAMSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsTIGR00574. dnl1. 1 hit.
PROSITEPS00697. DNA_LIGASE_A1. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameF0M945_ARTPP
AccessionPrimary (citable) accession number: F0M945
Entry history
Integrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: May 3, 2011
Last modified: February 19, 2014
This is version 18 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)