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F0M7D8 (F0M7D8_ARTPP) Unreviewed, UniProtKB/TrEMBL

Last modified October 16, 2013. Version 18. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Protein attributes

Sequence length419 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively By similarity. PIRNR PIRNR038800

Catalytic activity

L-3-hydroxykynurenine + H2O = 3-hydroxyanthranilate + L-alanine. PIRNR PIRNR038800

L-kynurenine + H2O = anthranilate + L-alanine. PIRNR PIRNR038800

Cofactor

Pyridoxal phosphate By similarity. PIRNR PIRNR038800

Pathway

Amino-acid degradation; L-kynurenine degradation; L-alanine and anthranilate from L-kynurenine: step 1/1. PIRNR PIRNR038800

Cofactor biosynthesis; NAD(+) biosynthesis; quinolinate from L-kynurenine: step 2/3. PIRNR PIRNR038800

Subunit structure

Homodimer By similarity. PIRNR PIRNR038800

Sequence similarities

Belongs to the kynureninase family. PIRNR PIRNR038800

Sequences

Sequence LengthMass (Da)Tools
F0M7D8 [UniParc].

Last modified May 3, 2011. Version 1.
Checksum: 5101A40A86752D77

FASTA41945,191
        10         20         30         40         50         60 
MSMDQQSPTK DAQTWLQQRA VELDNKDPLA HCRQHFIGTD TPLSYLDGNS LGRPLKRTPD 

        70         80         90        100        110        120 
DISRFITQGW GGRLIRGWDE EWLDLPQSIG DQLGRAVLGA APGQTIIADS TTVVLYKLIR 

       130        140        150        160        170        180 
AALAAVADPD RNELVLDTEN FPTDRYLVEG IALEEGLTLR WIQADPAAGV TVQQVREATG 

       190        200        210        220        230        240 
PRTAVVLLSQ VAYRSGHLAD LPAITAAVHD AGALVVWDLC HSAGSVEIGL DSAGVDFAAG 

       250        260        270        280        290        300 
CTYKYLNGGP GSPAFAYVNQ RHLASLNQPI WGWMGRKDAF EMAAGYEPAA GIRGFLSGTP 

       310        320        330        340        350        360 
AVFGMLAMRG TLDLIEEATM AAIREKSIQL TDFAVEVFDA LLAPLGAELG TPREPARRGS 

       370        380        390        400        410 
HITVDHPDFT KATVEALWAG DVIPDFRSPH GIRVGLSPLS TSFQETLQGM AAMRDRLQG 

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP002379 Genomic DNA. Translation: ADX72592.1.
RefSeqYP_004240726.1. NC_015145.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADX72592; ADX72592; Asphe3_14180.
GeneID10284790.
KEGGapn:Asphe3_14180.
PATRIC46861172. VBIArtPhe178037_1411.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK01556.

Enzyme and pathway databases

BioCycAPHE930171:GJHZ-1415-MONOMER.
UniPathwayUPA00253; UER00329.
UPA00334; UER00455.

Family and domain databases

Gene3D3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProIPR000192. Aminotrans_V/Cys_dSase.
IPR010111. Kynureninase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PANTHERPTHR14084. PTHR14084. 1 hit.
PfamPF00266. Aminotran_5. 1 hit.
[Graphical view]
PIRSFPIRSF038800. KYNU. 1 hit.
SUPFAMSSF53383. SSF53383. 1 hit.
ProtoNetSearch...

Entry information

Entry nameF0M7D8_ARTPP
AccessionPrimary (citable) accession number: F0M7D8
Entry history
Integrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: May 3, 2011
Last modified: October 16, 2013
This is version 18 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)