F0M0N2 (F0M0N2_VIBFN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
2-aminoethylphosphonate--pyruvate transaminase HAMAP-Rule MF_01376
EC=2.6.1.37 HAMAP-Rule MF_01376

Alternative name(s):
2-aminoethylphosphonate aminotransferase HAMAP-Rule MF_01376
AEP transaminase HAMAP-Rule MF_01376

Gene names

Name:	phnW HAMAP-Rule MF_01376
Ordered Locus Names:	vfu_B00116 EMBL ADT88368.1

Organism

Vibrio furnissii (strain DSM 14383 / NCTC 11218) [Complete proteome] [HAMAP]

Taxonomic identifier

903510 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Vibrionales › Vibrionaceae › Vibrio › Vibrio furnissii

Protein attributes

Sequence length	368 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Involved in phosphonate degradation By similarity. HAMAP-Rule MF_01376 SAAS SAAS012703
Catalytic activity	(2-aminoethyl)phosphonate + pyruvate = 2-phosphonoacetaldehyde + L-alanine. HAMAP-Rule MF_01376 SAAS SAAS012703
Cofactor	Pyridoxal phosphate By similarity. HAMAP-Rule MF_01376
Subunit structure	Homodimer By similarity. HAMAP-Rule MF_01376
Sequence similarities	Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily. HAMAP-Rule MF_01376

Ontologies

Keywords
Ligand	Pyridoxal phosphate HAMAP-Rule MF_01376 SAAS SAAS012703 Pyruvate HAMAP-Rule MF_01376 SAAS SAAS012703 EMBL ADT88368.1
Molecular function	Aminotransferase HAMAP-Rule MF_01376 SAAS SAAS012703 EMBL ADT88368.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	organic phosphonate catabolic process Inferred from electronic annotation. Source: InterPro
Molecular_function	2-aminoethylphosphonate-pyruvate transaminase activity Inferred from electronic annotation. Source: HAMAP pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Amino acid modifications
	Modified residue	193	1	N6-(pyridoxal phosphate)lysine By similarity HAMAP-Rule MF_01376

Sequences

	Sequence		Length	Mass (Da)
	F0M0N2 [UniParc]. Last modified May 3, 2011. Version 1. Checksum: 447323255165EFBA	FASTA	368	40,644
	10 20 30 40 50 60 MKNDYLLLTP GPLSTTETVR EAMLKDWCTW DDEYNKDIVE VIRQKLVALA TRHSGYTSVL 70 80 90 100 110 120 MQGSGTASVE ATIGSTLGQH GKLLVVDNGA YGARIAQIAA YLHIDCAIVS PGETAQPSLE 130 140 150 160 170 180 HIETCLQQDA TITHVAIVHC ETTTGMLNPI AEVVALAKRY GKTVIVDAMS SFGGIPMDIG 190 200 210 220 230 240 DLGIDFMISS ANKCIQGVPG FGFVIAKQSE LEQCQGQARS LSLDLYDQWQ CMEKNHGKWR 250 260 270 280 290 300 FTSPTHTVRA FYQALLELEQ EGGIAARHQR YQTNQTTLVR GMQSLGFTPL LDVSLHSPII 310 320 330 340 350 360 TSFYSPTHPD YQFAEFYQRL KAQGFVIYPG KVSHADCFRI GNIGDVHPHD IERLIEAVQN AMYWNVAS

References

[1]	"Complete genome sequence of a free-living Vibrio furnissii sp. nov. strain (NCTC 11218)." Lux T.M., Lee R., Love J. J. Bacteriol. 193:1487-1488(2011) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 14383 / NCTC 11218.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP002378 Genomic DNA. Translation: ADT88368.1.
RefSeq	YP_005048688.1. NC_016628.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ADT88368; ADT88368; vfu_B00116.
GeneID	11564375.
KEGG	vfu:vfu_B00116.
PATRIC	45430787. VBIVibFur169925_3170.
Organism-specific databases
CMR	Search...
Phylogenomic databases
KO	K03430.
Family and domain databases
Gene3D	3.40.640.10. 1 hit. 3.90.1150.10. 1 hit.
HAMAP	MF_01376. PhnW_aminotrans_5.
InterPro	IPR000192. Aminotrans_V/Cys_dSase. IPR012703. NH2EtPonate_pyrv_transaminase. IPR015424. PyrdxlP-dep_Trfase. IPR015421. PyrdxlP-dep_Trfase_major_sub1. IPR015422. PyrdxlP-dep_Trfase_major_sub2. IPR024169. SP_NH2Trfase/AEP_transaminase. [Graphical view]
PANTHER	PTHR21152:SF6. PTHR21152:SF6. 1 hit.
Pfam	PF00266. Aminotran_5. 1 hit. [Graphical view]
PIRSF	PIRSF000524. SPT. 1 hit.
SUPFAM	SSF53383. PyrdxlP-dep_Trfase_major. 1 hit.
TIGRFAMs	TIGR03301. PhnW-AepZ. 1 hit. TIGR02326. transamin_PhnW. 1 hit.
ProtoNet	Search...

Entry information

Entry name

F0M0N2_VIBFN

Accession

Primary (citable) accession number: F0M0N2

Entry history

Integrated into UniProtKB/TrEMBL:	May 3, 2011
Last sequence update:	May 3, 2011
Last modified:	April 3, 2013
This is version 15 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)