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Protein

2-aminoethylphosphonate--pyruvate transaminase

Gene

phnW

Organism
Vibrio furnissii (strain DSM 14383 / NCTC 11218)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Involved in phosphonate degradation.UniRule annotationSAAS annotation

Catalytic activityi

(2-aminoethyl)phosphonate + pyruvate = 2-phosphonoacetaldehyde + L-alanine.UniRule annotationSAAS annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotationSAAS annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminotransferaseUniRule annotationSAAS annotationImported, Transferase
LigandPyridoxal phosphateUniRule annotationSAAS annotation, PyruvateUniRule annotationSAAS annotationImported

Enzyme and pathway databases

BioCyciVFUR903510:G1GQK-3245-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
2-aminoethylphosphonate--pyruvate transaminaseUniRule annotation (EC:2.6.1.37UniRule annotation)
Alternative name(s):
2-aminoethylphosphonate aminotransferaseUniRule annotation
AEP transaminaseUniRule annotation
Short name:
AEPTUniRule annotation
Gene namesi
Name:phnWUniRule annotation
Ordered Locus Names:vfu_B00116Imported
OrganismiVibrio furnissii (strain DSM 14383 / NCTC 11218)Imported
Taxonomic identifieri903510 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio
Proteomesi
  • UP000007456 Componenti: Chromosome 2

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei193N6-(pyridoxal phosphate)lysineUniRule annotation1

Interactioni

Subunit structurei

Homodimer.UniRule annotation

Protein-protein interaction databases

STRINGi903510.vfu_B00116

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini36 – 309Aminotran_5InterPro annotationAdd BLAST274

Sequence similaritiesi

Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4107STF Bacteria
COG0075 LUCA
KOiK03430
OMAiIQACESS
OrthoDBiPOG091H03C8

Family and domain databases

Gene3Di3.40.640.101 hit
3.90.1150.102 hits
HAMAPiMF_01376 PhnW_aminotrans_5, 1 hit
InterProiView protein in InterPro
IPR000192 Aminotrans_V_dom
IPR012703 NH2EtPonate_pyrv_transaminase
IPR015424 PyrdxlP-dep_Trfase
IPR015422 PyrdxlP-dep_Trfase_dom1
IPR015421 PyrdxlP-dep_Trfase_major
IPR024169 SP_NH2Trfase/AEP_transaminase
PfamiView protein in Pfam
PF00266 Aminotran_5, 1 hit
PIRSFiPIRSF000524 SPT, 1 hit
SUPFAMiSSF53383 SSF53383, 1 hit
TIGRFAMsiTIGR03301 PhnW-AepZ, 1 hit
TIGR02326 transamin_PhnW, 1 hit

Sequencei

Sequence statusi: Complete.

F0M0N2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKNDYLLLTP GPLSTTETVR EAMLKDWCTW DDEYNKDIVE VIRQKLVALA
60 70 80 90 100
TRHSGYTSVL MQGSGTASVE ATIGSTLGQH GKLLVVDNGA YGARIAQIAA
110 120 130 140 150
YLHIDCAIVS PGETAQPSLE HIETCLQQDA TITHVAIVHC ETTTGMLNPI
160 170 180 190 200
AEVVALAKRY GKTVIVDAMS SFGGIPMDIG DLGIDFMISS ANKCIQGVPG
210 220 230 240 250
FGFVIAKQSE LEQCQGQARS LSLDLYDQWQ CMEKNHGKWR FTSPTHTVRA
260 270 280 290 300
FYQALLELEQ EGGIAARHQR YQTNQTTLVR GMQSLGFTPL LDVSLHSPII
310 320 330 340 350
TSFYSPTHPD YQFAEFYQRL KAQGFVIYPG KVSHADCFRI GNIGDVHPHD
360
IERLIEAVQN AMYWNVAS
Length:368
Mass (Da):40,644
Last modified:May 3, 2011 - v1
Checksum:i447323255165EFBA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002378 Genomic DNA Translation: ADT88368.1
RefSeqiWP_014257244.1, NC_016628.1

Genome annotation databases

EnsemblBacteriaiADT88368; ADT88368; vfu_B00116
KEGGivfu:vfu_B00116
PATRICifig|903510.3.peg.3170

Similar proteinsi

Entry informationi

Entry nameiF0M0N2_VIBFN
AccessioniPrimary (citable) accession number: F0M0N2
Entry historyiIntegrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: May 3, 2011
Last modified: February 28, 2018
This is version 49 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported