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F0LM71 (F0LM71_THEBM) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 17. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Lysine--tRNA ligase HAMAP-Rule MF_00177
EC=6.1.1.6 HAMAP-Rule MF_00177
Alternative name(s):
Lysyl-tRNA synthetase HAMAP-Rule MF_00177
Gene names
Name:lysS HAMAP-Rule MF_00177
Ordered Locus Names:TERMP_00942 EMBL ADT83918.1
OrganismThermococcus barophilus (strain DSM 11836 / MP) [Complete proteome] [HAMAP]
Taxonomic identifier391623 [NCBI]
Taxonomic lineageArchaea › Euryarchaeota › Thermococci › Thermococcales › Thermococcaceae › Thermococcus ›

Protein attributes

Sequence length526 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-lysine + tRNA(Lys) = AMP + diphosphate + L-lysyl-tRNA(Lys). HAMAP-Rule MF_00177

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00177.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family. RuleBase RU003489 HAMAP-Rule MF_00177

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Motif30 – 389"HIGH" region By similarity HAMAP-Rule MF_00177
Motif280 – 2845"KMSKS" region By similarity HAMAP-Rule MF_00177

Sequences

Sequence LengthMass (Da)Tools
F0LM71 [UniParc].

Last modified May 3, 2011. Version 1.
Checksum: ABB29ACD099E81AD

FASTA52661,498
        10         20         30         40         50         60 
MVHWADYMAE KIIRERGDKE EYVVESGITP SGYVHIGNFR ELFTAYIVGH ALKDKGKKVR 

        70         80         90        100        110        120 
HIHMWDDYDR FRKVPKNVPG EWKEYLTMPV SEVPDPWGCH NSYAEHFMEL FESEVEKLGI 

       130        140        150        160        170        180 
EVDFLRASRL YKTGEYAKDI RKALENREKI VAILNKFRDM AKQPHLEESW QPVQIYCPKC 

       190        200        210        220        230        240 
RKEADFIQWD GGWKVEYKCP HCGSEGKTDI REGNVKLRWR VDWPMRWAHF GVDFEPAGKD 

       250        260        270        280        290        300 
HLAAGSSFDT GREIIKTVYG KEPPLTLMYE FVGIKGQKGK MSGSKGNVIL LSDLYEVLEP 

       310        320        330        340        350        360 
GVIRFLYARH RPNKEIKIDL GLGLLNLYDE FDKVERIYFG LENAKNKEEE IELKRTYELS 

       370        380        390        400        410        420 
MPKIPERLVA QAPFRFLVVL VQMPHLDEGK IIEILKKQGH IPQDLAEEDT ERIKLRIMLA 

       430        440        450        460        470        480 
KNWVSKYAPD TVKFSLLQEP PRIEISEEIK EALNEVANWL ESREEFSVDE LNNIIFDAAK 

       490        500        510        520 
KRNIPSKQWF KILYQLFIGK DRGPRLASFL ASLDKDFVTR RLRLKA

« Hide

References

[1]"Complete genome sequence of the hyperthermophilic, piezophilic, heterotrophic, and carboxydotrophic archaeon Thermococcus barophilus MP."
Vannier P., Marteinsson V.T., Fridjonsson O.H., Oger P., Jebbar M.
J. Bacteriol. 193:1481-1482(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 11836 / MP.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP002372 Genomic DNA. Translation: ADT83918.1.
RefSeqYP_004071141.1. NC_014804.1.

3D structure databases

ProteinModelPortalF0LM71.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADT83918; ADT83918; TERMP_00942.
GeneID10041259.
KEGGtba:TERMP_00942.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000226938.
KOK04566.

Family and domain databases

Gene3D1.10.10.350. 1 hit.
2.30.30.300. 1 hit.
3.40.50.620. 2 hits.
HAMAPMF_00177. Lys_tRNA_synth_class1.
InterProIPR008925. aa-tRNA-synth_I_codon-bd.
IPR020751. aa-tRNA-synth_I_codon-bd_sub2.
IPR001412. aa-tRNA-synth_I_CS.
IPR002904. Lys-tRNA-ligase.
IPR023386. Lys-tRNA-ligase_insertion.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PfamPF01921. tRNA-synt_1f. 1 hit.
[Graphical view]
SUPFAMSSF48163. tRNA-synt_bind. 1 hit.
TIGRFAMsTIGR00467. lysS_arch. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameF0LM71_THEBM
AccessionPrimary (citable) accession number: F0LM71
Entry history
Integrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: May 3, 2011
Last modified: May 1, 2013
This is version 17 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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