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Protein

Phosphoenolpyruvate carboxylase

Gene

ppcA

Organism
Thermococcus barophilus (strain DSM 11836 / MP)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotation

Cofactori

Mg2+UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyaseUniRule annotation
Biological processCarbon dioxide fixationUniRule annotation
LigandMagnesiumUniRule annotation, PyruvateImported

Enzyme and pathway databases

BioCyciTBAR391623:G1GNI-1747-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcAUniRule annotation
Ordered Locus Names:TERMP_01753Imported
OrganismiThermococcus barophilus (strain DSM 11836 / MP)Imported
Taxonomic identifieri391623 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaeThermococcus
Proteomesi
  • UP000007478 Componenti: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi391623.TERMP_01753

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili319 – 339Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the PEPCase type 2 family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiarCOG04435 Archaea
COG1892 LUCA
HOGENOMiHOG000038601
KOiK01595
OMAiPAMNYGL
OrthoDBiPOG093Z01LI

Family and domain databases

HAMAPiMF_01904 PEPcase_type2, 1 hit
InterProiView protein in InterPro
IPR007566 PEP_COase_arc-type
IPR015813 Pyrv/PenolPyrv_Kinase-like_dom
PfamiView protein in Pfam
PF14010 PEPcase_2, 1 hit
PIRSFiPIRSF006677 UCP006677, 1 hit
SUPFAMiSSF51621 SSF51621, 1 hit
TIGRFAMsiTIGR02751 PEPCase_arch, 1 hit

Sequencei

Sequence statusi: Complete.

F0LK16-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIPKTMSTQH PDNVYIPFFA REPQLGGEDE IIEAFYAFSV LGIEEQMWDF
60 70 80 90 100
EGKEVDEFVV KKLLERYPHF FRKHKLGEDF RLTPRVPNPS VEKAEAKLLL
110 120 130 140 150
ETLESISRSA DYSKIFYGKE IAPIFEVILP MTTSANEINR VYDLYKRYIV
160 170 180 190 200
GKQYKRVYDV KLYEWIGKFF PEEINVIPLF ETKDAILNSA EILREYLHGK
210 220 230 240 250
DFEYQRVFLA RSDPAMNYGL ISAVVYDKYA LFKLQELEEE ESVSIYPIIG
260 270 280 290 300
VGSAPFRGHL VPENVENVLE EYRGAQTFTI QSSFKYDNPP REVIKAVEKI
310 320 330 340 350
KSSKRKEAEP INGQILLILR KYEIEYSKQI KALAKLVREV AKFVPSRRKR
360 370 380 390 400
KLHIGLFGYA RDVNGFALPR AIKFTASLYS LGVPPEVLGL NALSEKDVEV
410 420 430 440 450
ISNVYNGIYK DLSLAFRYFN PKSAEKFKFL RDILKMSQLF EFERNEEHCE
460 470
ITNKILDGEI NEELIIKAAS IRGFLG
Length:476
Mass (Da):55,184
Last modified:May 3, 2011 - v1
Checksum:i6F1B7A38A3A4F235
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002372 Genomic DNA Translation: ADT84728.1
RefSeqiWP_013468025.1, NC_014804.1

Genome annotation databases

EnsemblBacteriaiADT84728; ADT84728; TERMP_01753
GeneIDi10042069
KEGGitba:TERMP_01753
PATRICifig|391623.17.peg.1752

Similar proteinsi

Entry informationi

Entry nameiF0LK16_THEBM
AccessioniPrimary (citable) accession number: F0LK16
Entry historyiIntegrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: May 3, 2011
Last modified: February 28, 2018
This is version 38 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported