F0LB04 (F0LB04_AGRSH) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Error-prone DNA polymerase HAMAP-Rule MF_01902
EC=2.7.7.7 HAMAP-Rule MF_01902

Gene names

Name:	dnaE2 HAMAP-Rule MF_01902
Ordered Locus Names:	AGROH133_10927 EMBL ADY66386.1

Organism

Agrobacterium sp. (strain H13-3) (Rhizobium lupini (strain H13-3)) [Complete proteome] [HAMAP] EMBL ADY66386.1

Taxonomic identifier

861208 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Rhizobiaceae › Rhizobium/Agrobacterium group › Agrobacterium

Protein attributes

Sequence length	1091 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase By similarity. HAMAP-Rule MF_01902
Catalytic activity	Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). HAMAP-Rule MF_01902 SAAS SAAS011708
Subcellular location	Cytoplasm By similarity HAMAP-Rule MF_01902 SAAS SAAS011708.
Sequence similarities	Belongs to the DNA polymerase type-C family. DnaE2 subfamily. HAMAP-Rule MF_01902

Ontologies

Keywords
Biological process	DNA damage DNA repair HAMAP-Rule MF_01902 SAAS SAAS011708 DNA replication SAAS SAAS011708 HAMAP-Rule MF_01902
Cellular component	Cytoplasm HAMAP-Rule MF_01902 SAAS SAAS011708
Molecular function	DNA-directed DNA polymerase HAMAP-Rule MF_01902 SAAS SAAS011708 Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	DNA repair Inferred from electronic annotation. Source: HAMAP DNA replication Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	3'-5' exonuclease activity Inferred from electronic annotation. Source: InterPro DNA binding Inferred from electronic annotation. Source: InterPro DNA-directed DNA polymerase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	F0LB04 [UniParc]. Last modified May 3, 2011. Version 1. Checksum: BD7D5D187F252C8A	FASTA	1,091	123,004
	10 20 30 40 50 60 MSTPRYAELQ VTTHFSFLRG ASSCDELFEQ AKNLGIEALG IVDRNSLAAI PRAYEAADNH 70 80 90 100 110 120 GIRLVIGCRL DLDDDLSVLV YPMDRPAYGR LCRLLSVGKK RGGKGKCRLT WDDLVAYGEG 130 140 150 160 170 180 LIVVLLADLA DDLCALRLRR LKAAFADRAY MALSLRRRPN DQMRLFELSN MAAAADVPTV 190 200 210 220 230 240 VTNDVLFHVP ERRMLQDVVT CIRHNCTIDE AGFRRERHAD RYMKPPQEMH RLFARYPEAL 250 260 270 280 290 300 ARSLEIAKRC TFSLKELVYQ YPEERSLPGL TAQQALEKLV WEAAAGRYPD GLPEKVEKAL 310 320 330 340 350 360 HHELGLIGRL EYAPYFLTVN AIVQFARGEN ILCQGRGSAA NSVVCYVLGI TAIDPLKVDL 370 380 390 400 410 420 LFERFVSEER REPPDIDVDF EHQRREEVIQ WVYNTYGRDK AALCSVVTRY RGRGALRDVG 430 440 450 460 470 480 KVLGLPEDLT KLLSSQVWRW SEGVGEKQVQ ELNLNMEDRR LKLAFELANQ LVGTPRHHSQ 490 500 510 520 530 540 HPGGFVLTHD RLDELVPIEP AAMDDRQIIE WDKDDIDIVK FMKMDCLALG MLSCMRRGFN 550 560 570 580 590 600 MLEERTGVKY DLATVPQDDD PTYAMIQKAD TLGTFQIESR AQMSMLPRLK PKIFYDLVIQ 610 620 630 640 650 660 VAIVRPGPIQ GDMVHPYLRR RDKKEEEHYP KEELRGVLGK TLGVPLFQEQ AMRVAIECAG 670 680 690 700 710 720 FSPGKADQLR RAMATFKNVG TISKFRQDMI DGMVDRGYEQ EFAERIFKQL EGFGSYGFPE 730 740 750 760 770 780 SHAASFALIA YASSWLKCHH PDIFCTALLN SQPMGFYAPA QIVRDARDHG VEVRPVCVNN 790 800 810 820 830 840 SRFDCSLEPT GKKNANGKER YAVRLGLRMV KGLSNDHAAK IVACRQDRDF VSVDDLWRRA 850 860 870 880 890 900 GVPAAALVCL AEADAFLPSL SLSRREALWA IKALRDEPLP LFAAAAGREN AVVDELSEPS 910 920 930 940 950 960 VALRPMTDGG EVVQDYGHVG LTLREHPMSF LRRDLSRRRI VSCAEAVRVR DGTWLETAGL 970 980 990 1000 1010 1020 VLVRQRPGSA KGVIFMTLED ETGIANAVLW VKTFEKYRRV VLSAGMVGIY GKIQREGEVV 1030 1040 1050 1060 1070 1080 HLVAHRLTDL SEALASVGER NHPFPLPHGR GDEFHHGIPP DDHLNIRKRP PPATQDGDEV 1090 ERIKVISRNF H

References

[1]

"Complete genome sequencing of Agrobacterium sp. H13-3, the former Rhizobium lupini H13-3, reveals a tripartite genome consisting of a circular and a linear chromosome and an accessory plasmid but lacking a tumor-inducing Ti-plasmid." Wibberg D., Blom J., Jaenicke S., Kollin F., Rupp O., Scharf B., Schneiker-Bekel S., Sczcepanowski R., Goesmann A., Setubal J.C., Schmitt R., Puhler A., Schluter A. J. Biotechnol. 155:50-62(2011) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: H13-3 EMBL ADY66386.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP002249 Genomic DNA. Translation: ADY66386.1.
RefSeq	YP_004443477.1. NC_015508.1.
3D structure databases
ProteinModelPortal	F0LB04.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ADY66386; ADY66386; AGROH133_10927.
GeneID	10582362.
KEGG	agr:AGROH133_10927.
Organism-specific databases
CMR	Search...
Phylogenomic databases
KO	K14162.
Enzyme and pathway databases
BioCyc	ASP861208:GH59-3436-MONOMER.
Family and domain databases
HAMAP	MF_01902. DNApol_error_prone.
InterPro	IPR011708. DNA_pol3_alpha. IPR023073. DNA_pol_error_prone. IPR004365. NA-bd_OB_tRNA-helicase. IPR004013. PHP_C. IPR003141. Pol/His_phosphatase_N. IPR016195. Pol/histidinol_Pase-like. IPR004805. PolC_alpha. [Graphical view]
Pfam	PF07733. DNA_pol3_alpha. 1 hit. PF02811. PHP. 1 hit. PF01336. tRNA_anti. 1 hit. [Graphical view]
SMART	SM00481. POLIIIAc. 1 hit. [Graphical view]
SUPFAM	SSF89550. PHP-like. 1 hit.
TIGRFAMs	TIGR00594. polc. 1 hit.
ProtoNet	Search...

Entry information

Entry name

F0LB04_AGRSH

Accession

Primary (citable) accession number: F0LB04

Entry history

Integrated into UniProtKB/TrEMBL:	May 3, 2011
Last sequence update:	May 3, 2011
Last modified:	May 29, 2013
This is version 15 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)