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F0KUU8 (F0KUU8_YERE3) Unreviewed, UniProtKB/TrEMBL

Last modified May 29, 2013. Version 18. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase HAMAP-Rule MF_01165
EC=2.4.2.43 HAMAP-Rule MF_01165
Alternative name(s):
4-amino-4-deoxy-L-arabinose lipid A transferase HAMAP-Rule MF_01165
Lipid IV(A) 4-amino-4-deoxy-L-arabinosyltransferase HAMAP-Rule MF_01165
Undecaprenyl phosphate-alpha-L-Ara4N transferase HAMAP-Rule MF_01165
Gene names
Name:arnT HAMAP-Rule MF_01165
Ordered Locus Names:YE105_C2005 EMBL ADZ42501.1
OrganismYersinia enterocolitica subsp. palearctica serotype O:9 / biotype 3 (strain 105.5R(r)) [Complete proteome] [HAMAP] EMBL ADZ42501.1
Taxonomic identifier994476 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Yersinia ›

Protein attributes

Sequence length554 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides By similarity. HAMAP-Rule MF_01165 SAAS SAAS022839

Catalytic activity

4-amino-4-deoxy-alpha-L-arabinopyranosyl di-trans,octa-cis-undecaprenyl phosphate + lipid IV(A) = lipid II(A) + di-trans,octa-cis-undecaprenyl phosphate. HAMAP-Rule MF_01165 SAAS SAAS022839

Pathway

Lipopolysaccharide metabolism; 4-amino-4-deoxy-beta-L-arabinose-lipid A biosynthesis. HAMAP-Rule MF_01165 SAAS SAAS022839

Subcellular location

Cell inner membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_01165 SAAS SAAS022839.

Sequence similarities

Belongs to the glycosyltransferase 83 family. HAMAP-Rule MF_01165

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Transmembrane4 – 2421Helical; By similarity HAMAP-Rule MF_01165
Transmembrane87 – 10721Helical; By similarity HAMAP-Rule MF_01165
Transmembrane115 – 13521Helical; By similarity HAMAP-Rule MF_01165
Transmembrane178 – 19821Helical; By similarity HAMAP-Rule MF_01165
Transmembrane206 – 22621Helical; By similarity HAMAP-Rule MF_01165
Transmembrane262 – 28221Helical; By similarity HAMAP-Rule MF_01165
Transmembrane293 – 31321Helical; By similarity HAMAP-Rule MF_01165
Transmembrane315 – 33521Helical; By similarity HAMAP-Rule MF_01165
Transmembrane352 – 37221Helical; By similarity HAMAP-Rule MF_01165
Transmembrane384 – 40421Helical; By similarity HAMAP-Rule MF_01165
Transmembrane414 – 43421Helical; By similarity HAMAP-Rule MF_01165

Sequences

Sequence LengthMass (Da)Tools
F0KUU8 [UniParc].

Last modified May 3, 2011. Version 1.
Checksum: 69C16794E0A889BD

FASTA55462,293
        10         20         30         40         50         60 
MKLLKGSGAA LLALFFALVY LLPINSRLLW QPDETRYAEI SREMLQRGDW VVPHLLGIRY 

        70         80         90        100        110        120 
FEKPIAGYWF NNISQWIFGD TNFAVRFGSI FSTALSAVLV YWLATLLWRN RSTSFLATLI 

       130        140        150        160        170        180 
YLSMLLVFSI GSYAVLDPMI SLWLTASMVC FYLTLRAETA KQKIGAYLLL GLACGMGFMT 

       190        200        210        220        230        240 
KGFLALAVPV ISVLPIVIQQ KRVKDLIIFG PIAIVGAVIL SLPWALAIAQ REPDFWHYFF 

       250        260        270        280        290        300 
WVEHIQRFAE KDAQHKAPIW YYLPILCLGV LPWLGLLPAA ILKGWRERVA RPELFFLLSW 

       310        320        330        340        350        360 
VLMPLIFFSV AKGKLPTYIL PCMAPLSLLM AAYATDCANK MHMRALKVNG AINLILGFIC 

       370        380        390        400        410        420 
ALAILVIGMG WIGHLVAYGP QEHQKVILAT IAFAGWGIAG FATMRNNARH WRWAAACPLL 

       430        440        450        460        470        480 
FILLVGYLIP QQVIDSKQPQ NFIQNNFNEL SSSRYVATDS VGVAAGLAWE LKRSDILMFS 

       490        500        510        520        530        540 
EKGELSYGLN YADSGDHYIS AQDFSDWLVH ARQKGDVSLV IQLSRNEKIP DSLPAADKVS 

       550 
LMNRLALLWY KKTP

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References

[1]"Complete genome sequence of a Yersinia enterocolitica "Old World" (3/O:9) strain and comparison with the "New World" (1B/O:8) strain."
Wang X., Li Y., Jing H., Ren Y., Zhou Z., Wang S., Kan B., Xu J., Wang L.
J. Clin. Microbiol. 49:1251-1259(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 105.5R(r).

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP002246 Genomic DNA. Translation: ADZ42501.1.
RefSeqYP_004298204.1. NC_015224.1.

3D structure databases

ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADZ42501; ADZ42501; YE105_C2005.
GeneID10301840.
KEGGyep:YE105_C2005.
PATRIC47215930. VBIYerEnt184081_2154.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK07264.
OMACHSQKYL.

Enzyme and pathway databases

BioCycYENT994476:GHRB-2102-MONOMER.
UniPathwayUPA00037.

Family and domain databases

HAMAPMF_01165. ArnT_transfer.
InterProIPR022839. ArnT_tfrase.
IPR003342. Glyco_trans_39.
[Graphical view]
PfamPF02366. PMT. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameF0KUU8_YERE3
AccessionPrimary (citable) accession number: F0KUU8
Entry history
Integrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: May 3, 2011
Last modified: May 29, 2013
This is version 18 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info