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F0KUU8

- F0KUU8_YERE3

UniProt

F0KUU8 - F0KUU8_YERE3

Protein

Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase

Gene

arnT

Organism
Yersinia enterocolitica subsp. palearctica serotype O:9 / biotype 3 (strain 105.5R(r))
Status
Unreviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 24 (01 Oct 2014)
      Sequence version 1 (03 May 2011)
      Previous versions | rss
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    Functioni

    Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.UniRule annotationSAAS annotation

    Catalytic activityi

    4-amino-4-deoxy-alpha-L-arabinopyranosyl di-trans,octa-cis-undecaprenyl phosphate + lipid IV(A) = lipid II(A) + di-trans,octa-cis-undecaprenyl phosphate.UniRule annotationSAAS annotation

    Pathwayi

    GO - Molecular functioni

    1. mannosyltransferase activity Source: InterPro
    2. transferase activity, transferring pentosyl groups Source: InterPro

    GO - Biological processi

    1. lipid A biosynthetic process Source: UniProtKB-HAMAP
    2. lipopolysaccharide biosynthetic process Source: UniProtKB-KW
    3. protein O-linked glycosylation Source: InterPro

    Keywords - Molecular functioni

    GlycosyltransferaseUniRule annotationSAAS annotation, Transferase

    Keywords - Biological processi

    Lipid A biosynthesisUniRule annotationSAAS annotation, Lipid biosynthesis, Lipid metabolism, Lipopolysaccharide biosynthesisUniRule annotationSAAS annotation

    Enzyme and pathway databases

    BioCyciYENT994476:GHRB-2102-MONOMER.
    UniPathwayiUPA00037.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferaseUniRule annotation (EC:2.4.2.43UniRule annotation)
    Alternative name(s):
    4-amino-4-deoxy-L-arabinose lipid A transferaseUniRule annotation
    Lipid IV(A) 4-amino-4-deoxy-L-arabinosyltransferaseUniRule annotation
    Undecaprenyl phosphate-alpha-L-Ara4N transferaseUniRule annotation
    Gene namesi
    Name:arnTUniRule annotation
    Ordered Locus Names:YE105_C2005Imported
    OrganismiYersinia enterocolitica subsp. palearctica serotype O:9 / biotype 3 (strain 105.5R(r))Imported
    Taxonomic identifieri994476 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeYersinia
    ProteomesiUP000009271: Chromosome

    Subcellular locationi

    Cell inner membrane UniRule annotationSAAS annotation; Multi-pass membrane protein UniRule annotationSAAS annotation

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. plasma membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cell inner membraneUniRule annotationSAAS annotation, Cell membrane, Membrane

    Structurei

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei4 – 2421Helical;UniRule annotationAdd
    BLAST
    Transmembranei87 – 10721Helical;UniRule annotationAdd
    BLAST
    Transmembranei115 – 13521Helical;UniRule annotationAdd
    BLAST
    Transmembranei178 – 19821Helical;UniRule annotationAdd
    BLAST
    Transmembranei206 – 22621Helical;UniRule annotationAdd
    BLAST
    Transmembranei262 – 28221Helical;UniRule annotationAdd
    BLAST
    Transmembranei293 – 31321Helical;UniRule annotationAdd
    BLAST
    Transmembranei315 – 33521Helical;UniRule annotationAdd
    BLAST
    Transmembranei352 – 37221Helical;UniRule annotationAdd
    BLAST
    Transmembranei384 – 40421Helical;UniRule annotationAdd
    BLAST
    Transmembranei414 – 43421Helical;UniRule annotationAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the glycosyltransferase 83 family.UniRule annotation

    Keywords - Domaini

    Transmembrane, Transmembrane helixUniRule annotationSAAS annotation

    Phylogenomic databases

    KOiK07264.
    OMAiGNWIAPH.

    Family and domain databases

    HAMAPiMF_01165. ArnT_transfer.
    InterProiIPR022839. ArnT_tfrase.
    IPR003342. Glyco_trans_39.
    [Graphical view]
    PfamiPF02366. PMT. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    F0KUU8-1 [UniParc]FASTAAdd to Basket

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    MKLLKGSGAA LLALFFALVY LLPINSRLLW QPDETRYAEI SREMLQRGDW    50
    VVPHLLGIRY FEKPIAGYWF NNISQWIFGD TNFAVRFGSI FSTALSAVLV 100
    YWLATLLWRN RSTSFLATLI YLSMLLVFSI GSYAVLDPMI SLWLTASMVC 150
    FYLTLRAETA KQKIGAYLLL GLACGMGFMT KGFLALAVPV ISVLPIVIQQ 200
    KRVKDLIIFG PIAIVGAVIL SLPWALAIAQ REPDFWHYFF WVEHIQRFAE 250
    KDAQHKAPIW YYLPILCLGV LPWLGLLPAA ILKGWRERVA RPELFFLLSW 300
    VLMPLIFFSV AKGKLPTYIL PCMAPLSLLM AAYATDCANK MHMRALKVNG 350
    AINLILGFIC ALAILVIGMG WIGHLVAYGP QEHQKVILAT IAFAGWGIAG 400
    FATMRNNARH WRWAAACPLL FILLVGYLIP QQVIDSKQPQ NFIQNNFNEL 450
    SSSRYVATDS VGVAAGLAWE LKRSDILMFS EKGELSYGLN YADSGDHYIS 500
    AQDFSDWLVH ARQKGDVSLV IQLSRNEKIP DSLPAADKVS LMNRLALLWY 550
    KKTP 554
    Length:554
    Mass (Da):62,293
    Last modified:May 3, 2011 - v1
    Checksum:i69C16794E0A889BD
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002246 Genomic DNA. Translation: ADZ42501.1.
    RefSeqiYP_004298204.1. NC_015224.1.

    Genome annotation databases

    EnsemblBacteriaiADZ42501; ADZ42501; YE105_C2005.
    GeneIDi10301840.
    KEGGiyep:YE105_C2005.
    PATRICi47215930. VBIYerEnt184081_2154.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002246 Genomic DNA. Translation: ADZ42501.1 .
    RefSeqi YP_004298204.1. NC_015224.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ADZ42501 ; ADZ42501 ; YE105_C2005 .
    GeneIDi 10301840.
    KEGGi yep:YE105_C2005.
    PATRICi 47215930. VBIYerEnt184081_2154.

    Phylogenomic databases

    KOi K07264.
    OMAi GNWIAPH.

    Enzyme and pathway databases

    UniPathwayi UPA00037 .
    BioCyci YENT994476:GHRB-2102-MONOMER.

    Family and domain databases

    HAMAPi MF_01165. ArnT_transfer.
    InterProi IPR022839. ArnT_tfrase.
    IPR003342. Glyco_trans_39.
    [Graphical view ]
    Pfami PF02366. PMT. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Complete genome sequence of a Yersinia enterocolitica "Old World" (3/O:9) strain and comparison with the "New World" (1B/O:8) strain."
      Wang X., Li Y., Jing H., Ren Y., Zhou Z., Wang S., Kan B., Xu J., Wang L.
      J. Clin. Microbiol. 49:1251-1259(2011) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 105.5R(r)Imported.

    Entry informationi

    Entry nameiF0KUU8_YERE3
    AccessioniPrimary (citable) accession number: F0KUU8
    Entry historyi
    Integrated into UniProtKB/TrEMBL: May 3, 2011
    Last sequence update: May 3, 2011
    Last modified: October 1, 2014
    This is version 24 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3