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Protein

Alpha-amylase

Gene

CEA_P0166

Organism
Clostridium acetobutylicum (strain EA 2018)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Endohydrolysis of (1->4)-alpha-D-glucosidic linkages in polysaccharides containing three or more (1->4)-alpha-linked D-glucose units.UniRule annotation

GO - Molecular functioni

  1. alpha-amylase activity Source: UniProtKB-EC
  2. cation binding Source: InterPro
  3. starch binding Source: InterPro

GO - Biological processi

  1. carbohydrate metabolic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

GlycosidaseUniRule annotation, Hydrolase

Keywords - Biological processi

Carbohydrate metabolismUniRule annotation

Enzyme and pathway databases

BioCyciCACE863638:GLBA-4014-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Alpha-amylaseUniRule annotation (EC:3.2.1.1UniRule annotation)
Gene namesi
Ordered Locus Names:CEA_P0166Imported
Encoded oniPlasmid EA2018Imported
OrganismiClostridium acetobutylicum (strain EA 2018)Imported
Taxonomic identifieri863638 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium
ProteomesiUP000007476: Plasmid EA2018

Structurei

3D structure databases

ProteinModelPortaliF0KER4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyl hydrolase 13 family.UniRule annotation

Phylogenomic databases

KOiK01176.
OMAiGQNIFVV.

Family and domain databases

Gene3Di2.60.40.1180. 1 hit.
3.20.20.80. 1 hit.
InterProiIPR006048. A-amylase_b_C.
IPR006046. Alpha_amylase.
IPR005085. CBM_fam25.
IPR015902. Glyco_hydro_13.
IPR013780. Glyco_hydro_13_b.
IPR006047. Glyco_hydro_13_cat_dom.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERiPTHR10357. PTHR10357. 1 hit.
PfamiPF00128. Alpha-amylase. 1 hit.
PF03423. CBM_25. 3 hits.
[Graphical view]
PRINTSiPR00110. ALPHAAMYLASE.
SMARTiSM00632. Aamy_C. 1 hit.
SM01066. CBM_25. 3 hits.
[Graphical view]
SUPFAMiSSF51445. SSF51445. 1 hit.

Sequencei

Sequence statusi: Complete.

F0KER4-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSKRSKLLKR RMLSLSVICV LIGYGPVFNP VRSQAKVMTY SSENRELPEN
60 70 80 90 100
TKDGVMLHAF DWSFNNIKKE LPSIAAAGYK AVQVSPVQGT KSNSTNSSDW
110 120 130 140 150
WLLYQPTNQA IGNAQLGSYD DFKSLCSEAK NYGISIVVDV VMNHMANNGN
160 170 180 190 200
DDEVASEVDP SFKDPSLYHH NGQCTDWNNR QDVTQEGIGM PDLNTQSSAV
210 220 230 240 250
QSKAITFLNQ CVDAGATGFR FDAAKHIETD LGLDANKSWS GNYWENVLGS
260 270 280 290 300
LHNKSNLYIY GEVLQDGKVD NISAYESFMN VEASAYDGSL RGAIKSGDLT
310 320 330 340 350
NAQGMGGLDS NKCVDMLETH DEYEHNESKD LTDWQRKAGW AIAASRAGSV
360 370 380 390 400
PLFFDRPTGN IGSEGDALWK DSDVVAVNEF HNAMAGQNEY LRLQNNNKAM
410 420 430 440 450
IIERGSKGAV IVNEGDSFNL NTPTNLEDGN YDNHGSATDS LTVSQGRMTG
460 470 480 490 500
TVPANSIIVI YNKNSNPGSD RVTLSEQAAK AGDSVTITYD AGTTALKDAS
510 520 530 540 550
NVNLYWGYDG FSAATSKAMT SLGDNKWQTT ITVPKEVTKN VNFSFTDGTS
560 570 580 590 600
WDNNNGANWN IPLASNYLPH AGYKVDYDSS NLVSGNNFTI YYNGNLANSS
610 620 630 640 650
NVSLHWGVNG WSNMQNLAMV KDSNGFWEAT IAIPASSNTL NFCFTNGSSW
660 670 680 690 700
DNNNNNNWTL NTWSSVPKVQ VTPAPEACKQ ISVYYNGSLA SSASNITLHW
710 720 730 740 750
GCNGFTSPQD INMVKQADGR WLANITLPSG CYNVNMAFKD QSGTWDNNNS
760
NNYNFSSTNN
Length:760
Mass (Da):83,045
Last modified:May 3, 2011 - v1
Checksum:i10E146F40252F6D0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002119 Genomic DNA. Translation: ADZ22949.1.
RefSeqiWP_010890852.1. NC_017296.1.
YP_005673044.1. NC_017296.1.

Genome annotation databases

EnsemblBacteriaiADZ22949; ADZ22949; CEA_P0166.
GeneIDi12232697.
KEGGicay:CEA_P0166.
PATRICi47114904. VBICloAce167171_3957.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002119 Genomic DNA. Translation: ADZ22949.1.
RefSeqiWP_010890852.1. NC_017296.1.
YP_005673044.1. NC_017296.1.

3D structure databases

ProteinModelPortaliF0KER4.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiADZ22949; ADZ22949; CEA_P0166.
GeneIDi12232697.
KEGGicay:CEA_P0166.
PATRICi47114904. VBICloAce167171_3957.

Phylogenomic databases

KOiK01176.
OMAiGQNIFVV.

Enzyme and pathway databases

BioCyciCACE863638:GLBA-4014-MONOMER.

Family and domain databases

Gene3Di2.60.40.1180. 1 hit.
3.20.20.80. 1 hit.
InterProiIPR006048. A-amylase_b_C.
IPR006046. Alpha_amylase.
IPR005085. CBM_fam25.
IPR015902. Glyco_hydro_13.
IPR013780. Glyco_hydro_13_b.
IPR006047. Glyco_hydro_13_cat_dom.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERiPTHR10357. PTHR10357. 1 hit.
PfamiPF00128. Alpha-amylase. 1 hit.
PF03423. CBM_25. 3 hits.
[Graphical view]
PRINTSiPR00110. ALPHAAMYLASE.
SMARTiSM00632. Aamy_C. 1 hit.
SM01066. CBM_25. 3 hits.
[Graphical view]
SUPFAMiSSF51445. SSF51445. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Comparative genomic and transcriptomic analysis revealed genetic characteristics related to solvent formation and xylose utilization in Clostridium acetobutylicum EA 2018."
    Hu S., Zheng H., Gu Y., Zhao J., Zhang W., Yang Y., Wang S., Zhao G., Yang S., Jiang W.
    BMC Genomics 12:93-93(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: EA 2018Imported.

Entry informationi

Entry nameiF0KER4_CLOAE
AccessioniPrimary (citable) accession number: F0KER4
Entry historyi
Integrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: May 3, 2011
Last modified: January 7, 2015
This is version 23 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported, PlasmidImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.