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F0K7H8

- F0K7H8_CLOAE

UniProt

F0K7H8 - F0K7H8_CLOAE

Protein

Elongation factor Tu

Gene

tuf

Organism
Clostridium acetobutylicum (strain EA 2018)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 30 (01 Oct 2014)
      Sequence version 1 (03 May 2011)
      Previous versions | rss
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    Functioni

    This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.UniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi19 – 268GTPUniRule annotation
    Nucleotide bindingi81 – 855GTPUniRule annotation
    Nucleotide bindingi136 – 1394GTPUniRule annotation

    GO - Molecular functioni

    1. GTPase activity Source: InterPro
    2. GTP binding Source: UniProtKB-HAMAP
    3. translation elongation factor activity Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Elongation factorUniRule annotationImported

    Keywords - Biological processi

    Protein biosynthesis

    Keywords - Ligandi

    GTP-bindingUniRule annotation, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciCACE863638:GLBA-3217-MONOMER.
    CACE863638:GLBA-3231-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Elongation factor TuUniRule annotation
    Short name:
    EF-TuUniRule annotation
    Gene namesi
    Name:tufUniRule annotationImported
    Ordered Locus Names:CEA_G3141Imported, CEA_G3155Imported
    OrganismiClostridium acetobutylicum (strain EA 2018)Imported
    Taxonomic identifieri863638 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium
    ProteomesiUP000007476: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    CytoplasmUniRule annotation

    Interactioni

    Subunit structurei

    Monomer.UniRule annotation

    Structurei

    3D structure databases

    SMRiF0K7H8. Positions 3-397.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the GTP-binding elongation factor family. EF-Tu/EF-1A subfamily.UniRule annotation
    Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.UniRule annotation

    Phylogenomic databases

    KOiK02358.
    OMAiGTEMCMP.

    Family and domain databases

    Gene3Di3.40.50.300. 1 hit.
    HAMAPiMF_00118_B. EF_Tu_B.
    InterProiIPR000795. EF_GTP-bd_dom.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR009000. Transl_B-barrel.
    IPR009001. Transl_elong_EF1A/Init_IF2_C.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    IPR004541. Transl_elong_EFTu/EF1A_bac/org.
    IPR004160. Transl_elong_EFTu/EF1A_C.
    [Graphical view]
    PfamiPF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 1 hit.
    PF03143. GTP_EFTU_D3. 1 hit.
    [Graphical view]
    PRINTSiPR00315. ELONGATNFCT.
    SUPFAMiSSF50447. SSF50447. 1 hit.
    SSF50465. SSF50465. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEiPS00301. EFACTOR_GTP. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    F0K7H8-1 [UniParc]FASTAAdd to Basket

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    MAKEKFERTK PHVNIGTIGH VDHGKTTLTA AITTILAKEG KAKAFNYEEI    50
    DKAPEEKERG ITINTAHVEY ETENRHYAHV DCPGHADYVK NMITGAAQMD 100
    GAILVVSAAD GPMPQTREHI LLASRVGVEY IVVFLNKADQ VDDPELIDLV 150
    EMEVRELLNE YGFPGDDTPI VVGSALKALQ NPDDAEAIKP IKDLMAEVDA 200
    YIPTPERPTD KAFLMPIEDV FTITGRGTVA TGRVETGTLK VGDEVEIVGM 250
    KDEITKVVVT GVEMFRKILD SALAGDNIGA LLRGVQREDI ERGQVLAKPG 300
    SITPHNKFVG QVYVLKKEEG GRHTPFFNGY RPQFYFRTTD VTGSIQLPDG 350
    VEMVMPGDHI DMTVELITKV AMGDNLRFAI REGGRTVGSG VVTSIIE 397
    Length:397
    Mass (Da):43,453
    Last modified:May 3, 2011 - v1
    Checksum:iF031B2F700434452
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002118 Genomic DNA. Translation: ADZ22178.1.
    CP002118 Genomic DNA. Translation: ADZ22192.1.
    RefSeqiYP_005672273.1. NC_017295.1.
    YP_005672287.1. NC_017295.1.

    Genome annotation databases

    EnsemblBacteriaiADZ22178; ADZ22178; CEA_G3141.
    ADZ22192; ADZ22192; CEA_G3155.
    GeneIDi12233889.
    12233903.
    KEGGicay:CEA_G3141.
    cay:CEA_G3155.
    PATRICi47113278. VBICloAce167171_3171.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002118 Genomic DNA. Translation: ADZ22178.1 .
    CP002118 Genomic DNA. Translation: ADZ22192.1 .
    RefSeqi YP_005672273.1. NC_017295.1.
    YP_005672287.1. NC_017295.1.

    3D structure databases

    SMRi F0K7H8. Positions 3-397.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ADZ22178 ; ADZ22178 ; CEA_G3141 .
    ADZ22192 ; ADZ22192 ; CEA_G3155 .
    GeneIDi 12233889.
    12233903.
    KEGGi cay:CEA_G3141.
    cay:CEA_G3155.
    PATRICi 47113278. VBICloAce167171_3171.

    Phylogenomic databases

    KOi K02358.
    OMAi GTEMCMP.

    Enzyme and pathway databases

    BioCyci CACE863638:GLBA-3217-MONOMER.
    CACE863638:GLBA-3231-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.300. 1 hit.
    HAMAPi MF_00118_B. EF_Tu_B.
    InterProi IPR000795. EF_GTP-bd_dom.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR009000. Transl_B-barrel.
    IPR009001. Transl_elong_EF1A/Init_IF2_C.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    IPR004541. Transl_elong_EFTu/EF1A_bac/org.
    IPR004160. Transl_elong_EFTu/EF1A_C.
    [Graphical view ]
    Pfami PF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 1 hit.
    PF03143. GTP_EFTU_D3. 1 hit.
    [Graphical view ]
    PRINTSi PR00315. ELONGATNFCT.
    SUPFAMi SSF50447. SSF50447. 1 hit.
    SSF50465. SSF50465. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsi TIGR00485. EF-Tu. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEi PS00301. EFACTOR_GTP. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Comparative genomic and transcriptomic analysis revealed genetic characteristics related to solvent formation and xylose utilization in Clostridium acetobutylicum EA 2018."
      Hu S., Zheng H., Gu Y., Zhao J., Zhang W., Yang Y., Wang S., Zhao G., Yang S., Jiang W.
      BMC Genomics 12:93-93(2011) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: EA 2018Imported.

    Entry informationi

    Entry nameiF0K7H8_CLOAE
    AccessioniPrimary (citable) accession number: F0K7H8
    Entry historyi
    Integrated into UniProtKB/TrEMBL: May 3, 2011
    Last sequence update: May 3, 2011
    Last modified: October 1, 2014
    This is version 30 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3