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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Lactobacillus delbrueckii subsp. bulgaricus (strain 2038)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotationSAAS annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei138 – 1381UniRule annotation
Active sitei572 – 5721UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, PyruvateImported

Enzyme and pathway databases

BioCyciLDEL353496:GLF6-427-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
Ordered Locus Names:LBU_0412Imported
OrganismiLactobacillus delbrueckii subsp. bulgaricus (strain 2038)Imported
Taxonomic identifieri353496 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesLactobacillaceaeLactobacillus
ProteomesiUP000008126 Componenti: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

KOiK01595.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F0K0D8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTAKKLENNS NHAVIAEEVK ILTDLLDEST RHLVGDEEFA KIKGLVKIAA
60 70 80 90 100
SSDHSQLESQ IACLSNQEMI IVARYFATLP LLINITEDVD LATEVNLLNN
110 120 130 140 150
TDKDYLGKLE STVDLVAEKD NAAEILSHVN VVPVLTAHPT QVQRKTILEL
160 170 180 190 200
TNKIHDQLRR HRDVKASTIN RKEWTNQLRR YIEIIMQTDI IREKKLKVSN
210 220 230 240 250
EIKNVMVYYP GSLIPAITKL TARYKELARE KGLNVDGATP ITMGMWIGGD
260 270 280 290 300
RDGNPYVTAE TLRLSATIQS EVIFEYYVKA LNDLYRTVSV STSYVQPTPE
310 320 330 340 350
VAELAKLSAD NSPFRENEPY RRAFYYLESR LAHTEMELLD VFSKEAVVKK
360 370 380 390 400
EAALKAPVYK DAYEFKKDLE AIKRSLIQNH DRAVTGGHFD ALLEAIDVFG
410 420 430 440 450
FHLATIDMRQ DSSVNEACVA ELLKSARICD NYSDLDEEEK IQILLSELNN
460 470 480 490 500
DPRSLHSSNS PKSELLQREL KIYHTARLLK DTLGENVIKQ HIISHTESIS
510 520 530 540 550
DMLEQAIMLK EYGLLDSEKA RVQVVPLFET VEDLQNSREI MKRYLSFDIV
560 570 580 590 600
KRWVASKGNY QEIMLGYSDS NKDGGYLASC WNLYKAQTEL TAIGEEQGIK
610 620 630 640 650
ITFMHGRGGT VGRGGGPSYE AITSQPFGSI KDRIRTTEQG EIIQNKYGNK
660 670 680 690 700
DAAYYNLEML VSAAVDRIVS KQKVSQDHIQ DFTASMDGIV EDSNRVYREL
710 720 730 740 750
VFDNPHFHDY FFQATPIKEV SSLNIGSRPA ARKKITELSG LRAIPWVFSW
760 770 780 790 800
SQSRVMFPGW YGVGSAFKHF IDADPNNLKE LQEMYQCWPF FHSLLSNVDM
810 820 830 840 850
VLSKSNMEIA EKYADLCEDE ATRSVFDIIK KEWELTKEVI LQIEGHSKLL
860 870 880 890 900
EDNPSLERSL DYRLPYFNVL NYVQLEMIKR GRQEKLSGIY ESIIHITING

VASGLRNSG
Length:909
Mass (Da):103,322
Last modified:May 3, 2011 - v1
Checksum:i811DD4247AEBDF9D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000156 Genomic DNA. Translation: ADY84597.1.
RefSeqiWP_014564655.1. NC_017469.1.
YP_005851621.1. NC_017469.1.

Genome annotation databases

EnsemblBacteriaiADY84597; ADY84597; LBU_0412.
KEGGildl:LBU_0412.
PATRICi47128955. VBILacDel183177_0457.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000156 Genomic DNA. Translation: ADY84597.1.
RefSeqiWP_014564655.1. NC_017469.1.
YP_005851621.1. NC_017469.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiADY84597; ADY84597; LBU_0412.
KEGGildl:LBU_0412.
PATRICi47128955. VBILacDel183177_0457.

Phylogenomic databases

KOiK01595.

Enzyme and pathway databases

BioCyciLDEL353496:GLF6-427-MONOMER.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete sequencing and pan-genomic analysis of Lactobacillus delbrueckii subsp. bulgaricus reveal its genetic basis for industrial yogurt production."
    Hao P., Zheng H., Yu Y., Ding G., Gu W., Chen S., Yu Z., Ren S., Oda M., Konno T., Wang S., Li X., Ji Z.S., Zhao G.
    PLoS ONE 6:E15964-E15964(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 2038Imported.

Entry informationi

Entry nameiF0K0D8_LACD2
AccessioniPrimary (citable) accession number: F0K0D8
Entry historyi
Integrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: May 3, 2011
Last modified: April 1, 2015
This is version 21 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.