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F0J6E1 (F0J6E1_ACIMA) Unreviewed, UniProtKB/TrEMBL

Last modified May 29, 2013. Version 20. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Protein attributes

Sequence length357 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity. HAMAP-Rule MF_01201

Catalytic activity

L-alanine = D-alanine. RuleBase RU000608 HAMAP-Rule MF_01201 SAAS SAAS020622

Cofactor

Pyridoxal phosphate By similarity. RuleBase RU000608 HAMAP-Rule MF_01201 SAAS SAAS020622

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. HAMAP-Rule MF_01201 SAAS SAAS020622

Sequence similarities

Belongs to the alanine racemase family. HAMAP-Rule MF_01201 RuleBase RU004188

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site331Proton acceptor; specific for D-alanine By similarity HAMAP-Rule MF_01201
Active site2521Proton acceptor; specific for L-alanine By similarity HAMAP-Rule MF_01201
Binding site1301Substrate By similarity HAMAP-Rule MF_01201
Binding site3001Substrate; via amide nitrogen By similarity HAMAP-Rule MF_01201

Amino acid modifications

Modified residue331N6-(pyridoxal phosphate)lysine By similarity HAMAP-Rule MF_01201

Sequences

Sequence LengthMass (Da)Tools
F0J6E1 [UniParc].

Last modified May 3, 2011. Version 1.
Checksum: 5B639431682BF56F

FASTA35737,258
        10         20         30         40         50         60 
MNHPTLTIDP GAVAANWQAL AARHAGEVAG VVKADAYGLG AALIAPALAA AGCRSFFVAT 

        70         80         90        100        110        120 
LDEALSLRAL LPAARIGVLN GCPPGEEETM RARELRPVLG SLAACARWRG AAGDDEAPPS 

       130        140        150        160        170        180 
FLHLDTGMNR LGLDRDEAAH LIAHPTLLDG LGLTHVMTHL VAAEEPDASA NAAQRERFAA 

       190        200        210        220        230        240 
FAARFPWLRT SLANSSGLFL GPGFGSDLAR PGYALYGGNP TPTAANPMRP AIALAAPILQ 

       250        260        270        280        290        300 
IRAIASGETV GYNGTWRAAR PSRIATIGVG YADGLPRSLS NRLTARWQGK IIPVAGRLSM 

       310        320        330        340        350 
DLTTFDVTEH PDIAPGDVIE LIGPGHDIDA IAAEAGTIGY EILTSLGPRY RRVVKSV

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References

[1]"Whole genome sequence of Acidiphilium multivorum AIU301."
Narita-Yamada S., Nakamura S., Ito N., Takarada H., Katano Y., Nakazawa H., Hosoyama A., Yamada R., Fujita N.
Submitted (DEC-2010) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 11245 / JCM 8867 / AIU301.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AP012035 Genomic DNA. Translation: BAJ82558.1.
RefSeqYP_004285440.1. NC_015186.1.

3D structure databases

ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAJ82558; BAJ82558; ACMV_32110.
GeneID10320184.
KEGGamv:ACMV_32110.
PATRIC46815417. VBIAciMul178205_3637.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK01775.

Enzyme and pathway databases

BioCycAMUL926570:GI8V-3265-MONOMER.
UniPathwayUPA00042; UER00497.

Family and domain databases

Gene3D2.40.37.10. 1 hit.
HAMAPMF_01201. Ala_racemase.
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
[Graphical view]
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. Racem_decarbox_C. 1 hit.
TIGRFAMsTIGR00492. alr. 1 hit.
PROSITEPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameF0J6E1_ACIMA
AccessionPrimary (citable) accession number: F0J6E1
Entry history
Integrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: May 3, 2011
Last modified: May 29, 2013
This is version 20 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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