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E9QPN7

- E9QPN7_MOUSE

UniProt

E9QPN7 - E9QPN7_MOUSE

Protein
Submitted name:

Dedicator of cytokinesis protein 6

Gene

Dock6

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 27 (01 Oct 2014)
      Sequence version 1 (05 Apr 2011)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. guanyl-nucleotide exchange factor activity Source: InterPro

    GO - Biological processi

    1. small GTPase mediated signal transduction Source: InterPro

    Enzyme and pathway databases

    ReactomeiREACT_198649. Factors involved in megakaryocyte development and platelet production.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Dedicator of cytokinesis protein 6Imported
    Gene namesi
    Name:Dock6Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 9

    Organism-specific databases

    MGIiMGI:1914789. Dock6.

    PTM / Processingi

    Proteomic databases

    PRIDEiE9QPN7.

    Expressioni

    Gene expression databases

    BgeeiE9QPN7.

    Structurei

    3D structure databases

    ProteinModelPortaliE9QPN7.
    SMRiE9QPN7. Positions 1812-2084.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    GeneTreeiENSGT00740000115071.
    OMAiKVTSMFE.
    OrthoDBiEOG7P8P7G.
    TreeFamiTF313629.

    Family and domain databases

    InterProiIPR027007. DHR-1_domain.
    IPR027357. DHR-2.
    IPR026791. DOCK.
    IPR026798. DOCK6.
    IPR010703. DOCK_C.
    IPR021816. DOCK_C/D_N.
    [Graphical view]
    PANTHERiPTHR23317. PTHR23317. 1 hit.
    PTHR23317:SF65. PTHR23317:SF65. 1 hit.
    PfamiPF06920. Ded_cyto. 1 hit.
    PF14429. DOCK-C2. 1 hit.
    PF11878. DUF3398. 1 hit.
    [Graphical view]
    PROSITEiPS51650. DHR_1. 1 hit.
    PS51651. DHR_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    E9QPN7-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAASERRAFA HKINRTVAAE VRKQVSRERS GSPHSSRRSS SSLGVPLTEV     50
    IEPLDFEDVL LSRPPEVEPG PLRDLIEFPV DDLELLKQPR ECRTTESGVP 100
    EDGQLDAQVR AAVEMYSEDW VIVRRRYQHL STAYSPITTE TQREWQKGLT 150
    CQVFEQDTPG DERTGPEDVD DPQHCSGSPE DTPRSSGASG IFSLRNLAAD 200
    SLLPTLLEQA APEDVDRRNE ALRRQHRAPT LLTLYPAPDE DEAVERCSRP 250
    EPPREHFGQR ILVKCLSLKF EIEIEPIFGT LALYDVREKK KISENFYFDL 300
    NSDSVKGLLR AHGTHPAIST LARSAIFSVT YPSPDIFLVV KLEKVLQQGD 350
    ISECCEPYMV MKEADTAKNK EKLEKLRLAA EQFCTRLGRY RMPFAWTAVH 400
    LANIVSRPQD RDSDSEGERR PTWAERRRRG PQDRGYSGDD ACSFSSFRPA 450
    TLTVTNFFKQ EAERLSDEDL FKFLADMRRP SSLLRRLRPV TAQLKLDISP 500
    APENLHFCLS PDLLHVKPYP DPRGRPTKEI LEFPAREVYA PHSCYRNLLF 550
    VYPHSLNFSS RQGSVRNLAV RIQYMAGEDQ SQALPVIFGK SSCSEFTREA 600
    FTPVVYHNKS PEFYEEFKLR LPACVTENHH LFFTFYHVSC QPRPGTALET 650
    PVGFTWIPLL QHGRLRTGPF CLPVSVDQPP PSYSVLTPDV ALPGMRWVDG 700
    HKGVFSVELT AVSSVHPQDP HLDKFFTLVH VLEEGIFPFR LKETVLSEGT 750
    MEQELRASLA ALRLASPEPL VAFSHLVLDK LVRLVVRPPI ICGQMVNLGR 800
    GAFEAMAHVA SLVHRNLEAV QDSRGHCPLL ASYVHYAFRL PGGDLSLPGE 850
    APPATVQAAT LARGSGRPAS LYLARSKSIS SSNPDLAVVP GSVDDEVSRI 900
    LASKGVDRSH SWVNSAYAPG GSKAVLRRVP PYCGADPRQA IDRNSSRASS 950
    YLEASSSALP APQSRHTVQK LLHEELALQW VVSGSAVREL VLQHAWFFFQ 1000
    LMVKSMELHL LLGQRLDTPR KLRFPGRFLD DIAALVASVG LEVITRVHKD 1050
    MKLAERLNAS LAFFLSDLLS IADRGYIFSL VRAHYKQVAT RLQSAPNPTA 1100
    LLTLRMDFTR ILCSHEHYVT LNLPCCPLSP PASPSPSVSS TTSQSSTFSS 1150
    QAPDPKVTSM FELSGPFRQQ HFLSGLLLTE LALALDPEAE GASLLHKKAI 1200
    SAVHSLLCSH DVDSRYAEAT VKAKVAELYL PLLSLARDTL PQLHGFAEGS 1250
    GQRSRLASML DSDTEGEGDI GSTINPSVAM AIAGGPLAPG SRTSISQGPS 1300
    TAARSGCPLS AESSRTLLVC VLWVLKNAEP TLLQRWAADL ALPQLGRLLD 1350
    LLYLCLAAFE YKGKKAFERI NSLTFKKSLD MKARLEEAIL GTIGARQEMV 1400
    RRSRERSPFG NQENVRWRKS ATHWRQTSDR VDKTKDEMEH EALVDGNLAT 1450
    EASLVVLDTL ETIVQTVMLS EARESILSAV LKVVLYSLGS AQSALFLQHG 1500
    LATQRALVSK FPELLFEEDT ELCADLCLRL LRHCGSRIST IRMHASASLY 1550
    LLMRQNFEIG HNFARVKMLV TMSLSSLVGT TQNFSEEHLR KSLKTILTYA 1600
    EEDIGLRDST FAEQVQDLMF NLHMILTDTV KMKEHQEDPE MLMDLMYRIA 1650
    RGYQGSPDLR LTWLQNMAGK HAELGNHAEA AQCMVHAAAL VAEYLALLED 1700
    SRHLPVGCVS FQNVSSNVLE ESAISDDILS PDEEGFCSGK NFTELGLVGL 1750
    LEQAAGYFTM GGLYEAVNEV YKNLIPILEA HRDYKKLAAV HGKLQEAFTK 1800
    IMHQSSGWER VFGTYFRVGF YGTRFGDLDE QEFVYKEPSI TKLAEISHRL 1850
    EEFYTERFGD DVVEIIKDSN PVDKSKLDPQ KAYIQITYVE PHFDTYELKD 1900
    RVTYFDRNYG LRAFLFCTPF TPDGRAHGEL AEQHKRKTLL STEHAFPYIK 1950
    TRIRVCHREE TVLTPVEVAI EDMQKKTREL AFATEQDPPD AKMLQMVLQG 2000
    SVGPTVNQGP LEVAQVFLSE IPEDPKLFRH HNKLRLCFKD FCKKCEDALR 2050
    KNKALIGPDQ KEYHRELERH YSRLREALQP LLTQRLPQLL APSSTSLRSS 2100
    MNRSSFRKAD L 2111
    Length:2,111
    Mass (Da):236,565
    Last modified:April 5, 2011 - v1
    Checksum:i1080358DE7C20914
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC161371 Genomic DNA. No translation available.
    AC166992 Genomic DNA. No translation available.
    RefSeqiNP_796004.2. NM_177030.3.
    UniGeneiMm.128153.

    Genome annotation databases

    EnsembliENSMUST00000034728; ENSMUSP00000034728; ENSMUSG00000032198.
    GeneIDi319899.
    KEGGimmu:319899.
    UCSCiuc009omo.1. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC161371 Genomic DNA. No translation available.
    AC166992 Genomic DNA. No translation available.
    RefSeqi NP_796004.2. NM_177030.3.
    UniGenei Mm.128153.

    3D structure databases

    ProteinModelPortali E9QPN7.
    SMRi E9QPN7. Positions 1812-2084.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi E9QPN7.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000034728 ; ENSMUSP00000034728 ; ENSMUSG00000032198 .
    GeneIDi 319899.
    KEGGi mmu:319899.
    UCSCi uc009omo.1. mouse.

    Organism-specific databases

    CTDi 57572.
    MGIi MGI:1914789. Dock6.

    Phylogenomic databases

    GeneTreei ENSGT00740000115071.
    OMAi KVTSMFE.
    OrthoDBi EOG7P8P7G.
    TreeFami TF313629.

    Enzyme and pathway databases

    Reactomei REACT_198649. Factors involved in megakaryocyte development and platelet production.

    Miscellaneous databases

    NextBioi 395613.
    SOURCEi Search...

    Gene expression databases

    Bgeei E9QPN7.

    Family and domain databases

    InterProi IPR027007. DHR-1_domain.
    IPR027357. DHR-2.
    IPR026791. DOCK.
    IPR026798. DOCK6.
    IPR010703. DOCK_C.
    IPR021816. DOCK_C/D_N.
    [Graphical view ]
    PANTHERi PTHR23317. PTHR23317. 1 hit.
    PTHR23317:SF65. PTHR23317:SF65. 1 hit.
    Pfami PF06920. Ded_cyto. 1 hit.
    PF14429. DOCK-C2. 1 hit.
    PF11878. DUF3398. 1 hit.
    [Graphical view ]
    PROSITEi PS51650. DHR_1. 1 hit.
    PS51651. DHR_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6JImported.
    3. Ensembl
      Submitted (MAY-2011) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.

    Entry informationi

    Entry nameiE9QPN7_MOUSE
    AccessioniPrimary (citable) accession number: E9QPN7
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 5, 2011
    Last sequence update: April 5, 2011
    Last modified: October 1, 2014
    This is version 27 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3