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E9QPN7

- E9QPN7_MOUSE

UniProt

E9QPN7 - E9QPN7_MOUSE

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Protein
Submitted name:

Dedicator of cytokinesis protein 6

Gene

Dock6

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. guanyl-nucleotide exchange factor activity Source: InterPro

GO - Biological processi

  1. small GTPase mediated signal transduction Source: InterPro
Complete GO annotation...

Enzyme and pathway databases

ReactomeiREACT_198649. Factors involved in megakaryocyte development and platelet production.

Names & Taxonomyi

Protein namesi
Submitted name:
Dedicator of cytokinesis protein 6Imported
Gene namesi
Name:Dock6Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 9

Organism-specific databases

MGIiMGI:1914789. Dock6.

PTM / Processingi

Proteomic databases

PRIDEiE9QPN7.

Expressioni

Gene expression databases

BgeeiE9QPN7.

Structurei

3D structure databases

ProteinModelPortaliE9QPN7.
SMRiE9QPN7. Positions 1812-2084.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00760000119234.
OMAiKVTSMFE.
OrthoDBiEOG7P8P7G.
TreeFamiTF313629.

Family and domain databases

InterProiIPR027007. DHR-1_domain.
IPR027357. DHR-2.
IPR026791. DOCK.
IPR026798. DOCK6.
IPR010703. DOCK_C.
IPR021816. DOCK_C/D_N.
[Graphical view]
PANTHERiPTHR23317. PTHR23317. 1 hit.
PTHR23317:SF65. PTHR23317:SF65. 1 hit.
PfamiPF06920. Ded_cyto. 1 hit.
PF14429. DOCK-C2. 1 hit.
PF11878. DUF3398. 1 hit.
[Graphical view]
PROSITEiPS51650. DHR_1. 1 hit.
PS51651. DHR_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E9QPN7-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAASERRAFA HKINRTVAAE VRKQVSRERS GSPHSSRRSS SSLGVPLTEV
60 70 80 90 100
IEPLDFEDVL LSRPPEVEPG PLRDLIEFPV DDLELLKQPR ECRTTESGVP
110 120 130 140 150
EDGQLDAQVR AAVEMYSEDW VIVRRRYQHL STAYSPITTE TQREWQKGLT
160 170 180 190 200
CQVFEQDTPG DERTGPEDVD DPQHCSGSPE DTPRSSGASG IFSLRNLAAD
210 220 230 240 250
SLLPTLLEQA APEDVDRRNE ALRRQHRAPT LLTLYPAPDE DEAVERCSRP
260 270 280 290 300
EPPREHFGQR ILVKCLSLKF EIEIEPIFGT LALYDVREKK KISENFYFDL
310 320 330 340 350
NSDSVKGLLR AHGTHPAIST LARSAIFSVT YPSPDIFLVV KLEKVLQQGD
360 370 380 390 400
ISECCEPYMV MKEADTAKNK EKLEKLRLAA EQFCTRLGRY RMPFAWTAVH
410 420 430 440 450
LANIVSRPQD RDSDSEGERR PTWAERRRRG PQDRGYSGDD ACSFSSFRPA
460 470 480 490 500
TLTVTNFFKQ EAERLSDEDL FKFLADMRRP SSLLRRLRPV TAQLKLDISP
510 520 530 540 550
APENLHFCLS PDLLHVKPYP DPRGRPTKEI LEFPAREVYA PHSCYRNLLF
560 570 580 590 600
VYPHSLNFSS RQGSVRNLAV RIQYMAGEDQ SQALPVIFGK SSCSEFTREA
610 620 630 640 650
FTPVVYHNKS PEFYEEFKLR LPACVTENHH LFFTFYHVSC QPRPGTALET
660 670 680 690 700
PVGFTWIPLL QHGRLRTGPF CLPVSVDQPP PSYSVLTPDV ALPGMRWVDG
710 720 730 740 750
HKGVFSVELT AVSSVHPQDP HLDKFFTLVH VLEEGIFPFR LKETVLSEGT
760 770 780 790 800
MEQELRASLA ALRLASPEPL VAFSHLVLDK LVRLVVRPPI ICGQMVNLGR
810 820 830 840 850
GAFEAMAHVA SLVHRNLEAV QDSRGHCPLL ASYVHYAFRL PGGDLSLPGE
860 870 880 890 900
APPATVQAAT LARGSGRPAS LYLARSKSIS SSNPDLAVVP GSVDDEVSRI
910 920 930 940 950
LASKGVDRSH SWVNSAYAPG GSKAVLRRVP PYCGADPRQA IDRNSSRASS
960 970 980 990 1000
YLEASSSALP APQSRHTVQK LLHEELALQW VVSGSAVREL VLQHAWFFFQ
1010 1020 1030 1040 1050
LMVKSMELHL LLGQRLDTPR KLRFPGRFLD DIAALVASVG LEVITRVHKD
1060 1070 1080 1090 1100
MKLAERLNAS LAFFLSDLLS IADRGYIFSL VRAHYKQVAT RLQSAPNPTA
1110 1120 1130 1140 1150
LLTLRMDFTR ILCSHEHYVT LNLPCCPLSP PASPSPSVSS TTSQSSTFSS
1160 1170 1180 1190 1200
QAPDPKVTSM FELSGPFRQQ HFLSGLLLTE LALALDPEAE GASLLHKKAI
1210 1220 1230 1240 1250
SAVHSLLCSH DVDSRYAEAT VKAKVAELYL PLLSLARDTL PQLHGFAEGS
1260 1270 1280 1290 1300
GQRSRLASML DSDTEGEGDI GSTINPSVAM AIAGGPLAPG SRTSISQGPS
1310 1320 1330 1340 1350
TAARSGCPLS AESSRTLLVC VLWVLKNAEP TLLQRWAADL ALPQLGRLLD
1360 1370 1380 1390 1400
LLYLCLAAFE YKGKKAFERI NSLTFKKSLD MKARLEEAIL GTIGARQEMV
1410 1420 1430 1440 1450
RRSRERSPFG NQENVRWRKS ATHWRQTSDR VDKTKDEMEH EALVDGNLAT
1460 1470 1480 1490 1500
EASLVVLDTL ETIVQTVMLS EARESILSAV LKVVLYSLGS AQSALFLQHG
1510 1520 1530 1540 1550
LATQRALVSK FPELLFEEDT ELCADLCLRL LRHCGSRIST IRMHASASLY
1560 1570 1580 1590 1600
LLMRQNFEIG HNFARVKMLV TMSLSSLVGT TQNFSEEHLR KSLKTILTYA
1610 1620 1630 1640 1650
EEDIGLRDST FAEQVQDLMF NLHMILTDTV KMKEHQEDPE MLMDLMYRIA
1660 1670 1680 1690 1700
RGYQGSPDLR LTWLQNMAGK HAELGNHAEA AQCMVHAAAL VAEYLALLED
1710 1720 1730 1740 1750
SRHLPVGCVS FQNVSSNVLE ESAISDDILS PDEEGFCSGK NFTELGLVGL
1760 1770 1780 1790 1800
LEQAAGYFTM GGLYEAVNEV YKNLIPILEA HRDYKKLAAV HGKLQEAFTK
1810 1820 1830 1840 1850
IMHQSSGWER VFGTYFRVGF YGTRFGDLDE QEFVYKEPSI TKLAEISHRL
1860 1870 1880 1890 1900
EEFYTERFGD DVVEIIKDSN PVDKSKLDPQ KAYIQITYVE PHFDTYELKD
1910 1920 1930 1940 1950
RVTYFDRNYG LRAFLFCTPF TPDGRAHGEL AEQHKRKTLL STEHAFPYIK
1960 1970 1980 1990 2000
TRIRVCHREE TVLTPVEVAI EDMQKKTREL AFATEQDPPD AKMLQMVLQG
2010 2020 2030 2040 2050
SVGPTVNQGP LEVAQVFLSE IPEDPKLFRH HNKLRLCFKD FCKKCEDALR
2060 2070 2080 2090 2100
KNKALIGPDQ KEYHRELERH YSRLREALQP LLTQRLPQLL APSSTSLRSS
2110
MNRSSFRKAD L
Length:2,111
Mass (Da):236,565
Last modified:April 5, 2011 - v1
Checksum:i1080358DE7C20914
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC161371 Genomic DNA. No translation available.
AC166992 Genomic DNA. No translation available.
RefSeqiNP_796004.2. NM_177030.3.
UniGeneiMm.128153.

Genome annotation databases

EnsembliENSMUST00000034728; ENSMUSP00000034728; ENSMUSG00000032198.
GeneIDi319899.
KEGGimmu:319899.
UCSCiuc009omo.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC161371 Genomic DNA. No translation available.
AC166992 Genomic DNA. No translation available.
RefSeqi NP_796004.2. NM_177030.3.
UniGenei Mm.128153.

3D structure databases

ProteinModelPortali E9QPN7.
SMRi E9QPN7. Positions 1812-2084.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi E9QPN7.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000034728 ; ENSMUSP00000034728 ; ENSMUSG00000032198 .
GeneIDi 319899.
KEGGi mmu:319899.
UCSCi uc009omo.1. mouse.

Organism-specific databases

CTDi 57572.
MGIi MGI:1914789. Dock6.

Phylogenomic databases

GeneTreei ENSGT00760000119234.
OMAi KVTSMFE.
OrthoDBi EOG7P8P7G.
TreeFami TF313629.

Enzyme and pathway databases

Reactomei REACT_198649. Factors involved in megakaryocyte development and platelet production.

Miscellaneous databases

NextBioi 395613.
SOURCEi Search...

Gene expression databases

Bgeei E9QPN7.

Family and domain databases

InterProi IPR027007. DHR-1_domain.
IPR027357. DHR-2.
IPR026791. DOCK.
IPR026798. DOCK6.
IPR010703. DOCK_C.
IPR021816. DOCK_C/D_N.
[Graphical view ]
PANTHERi PTHR23317. PTHR23317. 1 hit.
PTHR23317:SF65. PTHR23317:SF65. 1 hit.
Pfami PF06920. Ded_cyto. 1 hit.
PF14429. DOCK-C2. 1 hit.
PF11878. DUF3398. 1 hit.
[Graphical view ]
PROSITEi PS51650. DHR_1. 1 hit.
PS51651. DHR_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  3. Ensembl
    Submitted (MAY-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiE9QPN7_MOUSE
AccessioniPrimary (citable) accession number: E9QPN7
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: October 29, 2014
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3