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Protein
Submitted name:

Inner nuclear membrane protein Man1

Gene

Lemd3

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Inner nuclear membrane protein Man1Imported
Gene namesi
Name:Lemd3Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 10

Organism-specific databases

MGIiMGI:3580376. Lemd3.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei480 – 501HelicalSequence analysisAdd BLAST22
Transmembranei642 – 659HelicalSequence analysisAdd BLAST18

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

MaxQBiE9QP59.
PaxDbiE9QP59.
PRIDEiE9QP59.

Expressioni

Gene expression databases

BgeeiENSMUSG00000048661.
ExpressionAtlasiE9QP59. baseline and differential.
GenevisibleiE9QP59. MM.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000113103.

Structurei

3D structure databases

ProteinModelPortaliE9QP59.
SMRiE9QP59.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini7 – 51LEMInterPro annotationAdd BLAST45

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili40 – 64Sequence analysisAdd BLAST25

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG0147. Eukaryota.
ENOG410XP20. LUCA.
GeneTreeiENSGT00530000063791.
KOiK19410.
TreeFamiTF315385.

Family and domain databases

Gene3Di1.10.720.40. 1 hit.
3.30.70.330. 1 hit.
InterProiIPR018996. Inner-Nucl-membr_MAN1.
IPR011015. LEM/LEM-like_dom.
IPR003887. LEM_dom.
IPR012677. Nucleotide-bd_a/b_plait.
[Graphical view]
PfamiPF03020. LEM. 1 hit.
PF09402. MSC. 1 hit.
[Graphical view]
SMARTiSM00540. LEM. 1 hit.
[Graphical view]
SUPFAMiSSF54928. SSF54928. 1 hit.
SSF63451. SSF63451. 1 hit.
PROSITEiPS50954. LEM. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E9QP59-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAATAAAAP QQLSDEELFS QLRRYGLSPG PVTESTRPVY LKKLKKLREE
60 70 80 90 100
EQQQQQQQQQ QQHRAGGRGN KTRNSNNNNT ATAMGGRPGS GDLAYLRSPA
110 120 130 140 150
GLGRLSASAA ESPVAGGSGG AAAVPAAGSK VLLGFSSDES DVEASPREQA
160 170 180 190 200
GGGGARRDRA ALQYRGLRAP PAPPAAGEVT GGHPGERRKP HSWWGARRPA
210 220 230 240 250
GPEPQPPAAG SDGAAEDADE ELADGEDRDP EAEEPLWASR TVNGSRLLPY
260 270 280 290 300
SSCREHYSDS EEEEEEGEED GDVAPARQVL KDDSLARHRP RRSHSKPFSA
310 320 330 340 350
LTAKSGGSRQ ETSVQGGGAL AMNDRAAAAG SLDRSRNLEE AAAEPGGGGG
360 370 380 390 400
GGCGCDPVDS IPRYRAGAKK LAPLLSPPSP DGDSTLESPT GPLLKTNNHI
410 420 430 440 450
GGGAFGVDSP GLYANSLPPG ATAAAAPGTL RINHANHTGS NHTYLKTAYG
460 470 480 490 500
KPKLCEPEEE LLQQFKREEV SPTGSFSAHY LSMFLLTAAC LFFLILGLTY
510 520 530 540 550
LGMRGTGVPE DGGLIKNPFD ETFGKIQESE KNLLMSTLYK LHDRLAQIAG
560 570 580 590 600
DHECGSSSQR MLSVQEAAAY LKNLGPEYED VFNTSLLWIF KNGKDVGIRC
610 620 630 640 650
VGYGPEEDLT NITDVQFLQS TRPQMPFWCR FRRAFITVTH RLLLLCLGVV
660 670 680 690 700
LVCVALRYMR YRWTKEEEET RQMYDMVVKI IDVLRSHNEA CQETKDLQPY
710 720 730 740 750
MPLPHVRDSL IQPQDRKKMK KVWDRAVDFL AANESRVRTE TRRVGGADFL
760 770 780 790 800
VWRWIQPSAS CDKTLVIPSK VWQGQAFHLD RRNSPPNSLT PCLKIRNMFD
810 820 830 840 850
PVMEIGDHWH LAIQEAILEK CSDNDGIVHI AVDRNSREGC VYVKCLSPEY
860 870 880 890 900
AGKAFKALHG SWFDGKLVTV KYLRLDRYHH RFPQALTCNT PLKPANKHMN
910
SLSHLRLRTG LANSQGSS
Length:918
Mass (Da):100,166
Last modified:April 5, 2011 - v1
Checksum:iC17647DAD36292E5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC140381 Genomic DNA. No translation available.
RefSeqiNP_001074662.2. NM_001081193.2.
UniGeneiMm.339371.

Genome annotation databases

EnsembliENSMUST00000119944; ENSMUSP00000113103; ENSMUSG00000048661.
GeneIDi380664.
KEGGimmu:380664.
UCSCiuc007hfi.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC140381 Genomic DNA. No translation available.
RefSeqiNP_001074662.2. NM_001081193.2.
UniGeneiMm.339371.

3D structure databases

ProteinModelPortaliE9QP59.
SMRiE9QP59.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000113103.

Proteomic databases

MaxQBiE9QP59.
PaxDbiE9QP59.
PRIDEiE9QP59.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000119944; ENSMUSP00000113103; ENSMUSG00000048661.
GeneIDi380664.
KEGGimmu:380664.
UCSCiuc007hfi.1. mouse.

Organism-specific databases

CTDi23592.
MGIiMGI:3580376. Lemd3.

Phylogenomic databases

eggNOGiKOG0147. Eukaryota.
ENOG410XP20. LUCA.
GeneTreeiENSGT00530000063791.
KOiK19410.
TreeFamiTF315385.

Miscellaneous databases

ChiTaRSiLemd3. mouse.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000048661.
ExpressionAtlasiE9QP59. baseline and differential.
GenevisibleiE9QP59. MM.

Family and domain databases

Gene3Di1.10.720.40. 1 hit.
3.30.70.330. 1 hit.
InterProiIPR018996. Inner-Nucl-membr_MAN1.
IPR011015. LEM/LEM-like_dom.
IPR003887. LEM_dom.
IPR012677. Nucleotide-bd_a/b_plait.
[Graphical view]
PfamiPF03020. LEM. 1 hit.
PF09402. MSC. 1 hit.
[Graphical view]
SMARTiSM00540. LEM. 1 hit.
[Graphical view]
SUPFAMiSSF54928. SSF54928. 1 hit.
SSF63451. SSF63451. 1 hit.
PROSITEiPS50954. LEM. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiE9QP59_MOUSE
AccessioniPrimary (citable) accession number: E9QP59
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: November 2, 2016
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.