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Protein
Submitted name:

Regulator of G-protein-signaling 11

Gene

Rgs11

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. G-protein beta-subunit binding Source: MGI
  2. GTPase activator activity Source: GO_Central
  3. signal transducer activity Source: InterPro

GO - Biological processi

  1. G-protein coupled receptor signaling pathway Source: MGI
  2. intracellular signal transduction Source: InterPro
  3. positive regulation of GTPase activity Source: GOC
  4. termination of G-protein coupled receptor signaling pathway Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Regulator of G-protein-signaling 11Imported
Gene namesi
Name:Rgs11Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589 Componenti: Chromosome 17

Organism-specific databases

MGIiMGI:1354739. Rgs11.

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: GO_Central
  2. dendrite terminus Source: MGI
  3. heterotrimeric G-protein complex Source: InterPro
  4. plasma membrane Source: GO_Central
  5. protein complex Source: MGI
Complete GO annotation...

Expressioni

Gene expression databases

BgeeiE9QNN3.
ExpressionAtlasiE9QNN3. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliE9QNN3.
SMRiE9QNN3. Positions 13-422.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains 1 RGS domain.UniRule annotation

Phylogenomic databases

GeneTreeiENSGT00760000119142.
OrthoDBiEOG7BZVS5.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
1.10.196.10. 1 hit.
4.10.260.10. 1 hit.
InterProiIPR000591. DEP_dom.
IPR015898. G-protein_gamma-like_dom.
IPR016137. RGS.
IPR024066. RGS_subdom1.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00610. DEP. 1 hit.
PF00631. G-gamma. 1 hit.
PF00615. RGS. 1 hit.
[Graphical view]
PRINTSiPR01301. RGSPROTEIN.
SMARTiSM00049. DEP. 1 hit.
SM00224. GGL. 1 hit.
SM00315. RGS. 1 hit.
[Graphical view]
SUPFAMiSSF48097. SSF48097. 1 hit.
SSF48670. SSF48670. 1 hit.
PROSITEiPS50186. DEP. 1 hit.
PS50132. RGS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E9QNN3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVTRCTPHGG CSRMQRPHLS KMERVVVSMQ DPDQGVKMRS QRLLITVIPH
60 70 80 90 100
AVAGRDLVEW LVQKFCILED EALHLGTLLA QHGYIYPLRE SRDLTLRPDE
110 120 130 140 150
TPYRFQTPYF WTSTMWPAAE LDYAIYLAKK NIQKQGALVD YEKEHYALLH
160 170 180 190 200
KKINHAWDLV LMQAREQLRA AKQRRKGDRM VISCQEQTYW LVNKPPPGAP
210 220 230 240 250
NILEQGPERG SYNPSHMQMS SDFYKCEIEC FRKALGRNRV KSSACLEAYL
260 270 280 290 300
KFSSQHGPHD PIMSGCLPSN PWITDDVTYW AMNAPNVAAP TKLRVERWSF
310 320 330 340 350
SFRELLDDPV GRAHFMDFLQ KEFSAENLSF WEACEELRFG GQAQVPTLVD
360 370 380 390 400
SVYQQFLAPG AARWINIDSR TMERTLEGLR QPHRYVLDAA QLHIYMLMKK
410 420 430 440 450
DSYPRFLKSD IYKGLLEEAV IPLETKRWPF PFLRKPLHSS PSPALQSTPR
460
EPAATSSPEG ADGE
Length:464
Mass (Da):53,440
Last modified:April 5, 2011 - v1
Checksum:iED161C58685F2FDD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC126438 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSMUST00000122058; ENSMUSP00000113885; ENSMUSG00000024186.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC126438 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliE9QNN3.
SMRiE9QNN3. Positions 13-422.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000122058; ENSMUSP00000113885; ENSMUSG00000024186.

Organism-specific databases

MGIiMGI:1354739. Rgs11.

Phylogenomic databases

GeneTreeiENSGT00760000119142.
OrthoDBiEOG7BZVS5.

Miscellaneous databases

ChiTaRSiRgs11. mouse.
NextBioi35556076.
SOURCEiSearch...

Gene expression databases

BgeeiE9QNN3.
ExpressionAtlasiE9QNN3. baseline and differential.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
1.10.196.10. 1 hit.
4.10.260.10. 1 hit.
InterProiIPR000591. DEP_dom.
IPR015898. G-protein_gamma-like_dom.
IPR016137. RGS.
IPR024066. RGS_subdom1.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00610. DEP. 1 hit.
PF00631. G-gamma. 1 hit.
PF00615. RGS. 1 hit.
[Graphical view]
PRINTSiPR01301. RGSPROTEIN.
SMARTiSM00049. DEP. 1 hit.
SM00224. GGL. 1 hit.
SM00315. RGS. 1 hit.
[Graphical view]
SUPFAMiSSF48097. SSF48097. 1 hit.
SSF48670. SSF48670. 1 hit.
PROSITEiPS50186. DEP. 1 hit.
PS50132. RGS. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Ensembl
    Submitted (MAY-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiE9QNN3_MOUSE
AccessioniPrimary (citable) accession number: E9QNN3
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: February 4, 2015
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.