E9QNN3 (E9QNN3_MOUSE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Regulator of G-protein-signaling 11 Ensembl ENSMUSP00000113885

Gene names

Name:

Rgs11 Ensembl ENSMUSP00000113885 MGI 1354739

Organism

Mus musculus (Mouse) [Reference proteome] Ensembl ENSMUSP00000113885

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	464 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities	Contains 1 RGS domain. RuleBase RU003298
Caution	The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSMUSP00000113885

Ontologies

Keywords
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	G-protein coupled receptor signaling pathway Traceable author statement PubMed 11342430. Source: MGI intracellular signal transduction Inferred from electronic annotation. Source: InterPro termination of G-protein coupled receptor signaling pathway Inferred from electronic annotation. Source: InterPro
Cellular_component	cytoplasm Inferred from Biological aspect of Ancestor. Source: RefGenome dendrite terminus Inferred from direct assay PubMed 22689652. Source: MGI heterotrimeric G-protein complex Inferred from electronic annotation. Source: InterPro plasma membrane Inferred from Biological aspect of Ancestor. Source: RefGenome protein complex Inferred from sequence orthology PubMed 18468998. Source: MGI
Molecular_function	GTPase activator activity Inferred from Biological aspect of Ancestor. Source: RefGenome signal transducer activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	E9QNN3 [UniParc]. Last modified April 5, 2011. Version 1. Checksum: ED161C58685F2FDD	FASTA	464	53,440
	10 20 30 40 50 60 MVTRCTPHGG CSRMQRPHLS KMERVVVSMQ DPDQGVKMRS QRLLITVIPH AVAGRDLVEW 70 80 90 100 110 120 LVQKFCILED EALHLGTLLA QHGYIYPLRE SRDLTLRPDE TPYRFQTPYF WTSTMWPAAE 130 140 150 160 170 180 LDYAIYLAKK NIQKQGALVD YEKEHYALLH KKINHAWDLV LMQAREQLRA AKQRRKGDRM 190 200 210 220 230 240 VISCQEQTYW LVNKPPPGAP NILEQGPERG SYNPSHMQMS SDFYKCEIEC FRKALGRNRV 250 260 270 280 290 300 KSSACLEAYL KFSSQHGPHD PIMSGCLPSN PWITDDVTYW AMNAPNVAAP TKLRVERWSF 310 320 330 340 350 360 SFRELLDDPV GRAHFMDFLQ KEFSAENLSF WEACEELRFG GQAQVPTLVD SVYQQFLAPG 370 380 390 400 410 420 AARWINIDSR TMERTLEGLR QPHRYVLDAA QLHIYMLMKK DSYPRFLKSD IYKGLLEEAV 430 440 450 460 IPLETKRWPF PFLRKPLHSS PSPALQSTPR EPAATSSPEG ADGE

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Lineage-specific biology revealed by a finished genome assembly of the mouse." Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. , Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P. PLoS Biol. 7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: C57BL/6J Ensembl ENSMUSP00000113885.
[2]	Ensembl Submitted (MAY-2011) to UniProtKB Cited for: IDENTIFICATION. Strain: C57BL/6J Ensembl ENSMUSP00000113885.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC126438 Genomic DNA. No translation available.
IPI	IPI00131162.
3D structure databases
ProteinModelPortal	E9QNN3.
SMR	E9QNN3. Positions 13-422.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSMUST00000122058; ENSMUSP00000113885; ENSMUSG00000024186.
Organism-specific databases
MGI	MGI:1354739. Rgs11.
Phylogenomic databases
GeneTree	ENSGT00700000104259.
Gene expression databases
ArrayExpress	E9QNN3.
Bgee	E9QNN3.
Family and domain databases
Gene3D	1.10.10.10. 1 hit. 1.10.196.10. 1 hit. 4.10.260.10. 1 hit.
InterPro	IPR000591. DEP_dom. IPR015898. G-protein_gamma-like_dom. IPR000342. Regulat_G_prot_signal. IPR024066. Regulat_G_prot_signal_dom1. IPR016137. Regulat_G_prot_signal_superfam. IPR011991. WHTH_DNA-bd_dom. [Graphical view]
Pfam	PF00610. DEP. 1 hit. PF00631. G-gamma. 1 hit. PF00615. RGS. 1 hit. [Graphical view]
PRINTS	PR01301. RGSPROTEIN.
SMART	SM00049. DEP. 1 hit. SM00224. GGL. 1 hit. SM00315. RGS. 1 hit. [Graphical view]
SUPFAM	SSF48670. G-protein_gamma-like. 1 hit. SSF48097. Regulat_G_prot_signal_superfam. 1 hit.
PROSITE	PS50186. DEP. 1 hit. PS50132. RGS. 1 hit. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	RGS11. mouse.
NextBio	35556076.
SOURCE	Search...

Entry information

Entry name

E9QNN3_MOUSE

Accession

Primary (citable) accession number: E9QNN3

Entry history

Integrated into UniProtKB/TrEMBL:	April 5, 2011
Last sequence update:	April 5, 2011
Last modified:	May 1, 2013
This is version 22 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)