E9QN59 (E9QN59_MOUSE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Mitogen-activated protein kinase 10 Ensembl ENSMUSP00000108469

Gene names

Name:

Mapk10 Ensembl ENSMUSP00000108469 MGI 1346863

Organism

Mus musculus (Mouse) [Reference proteome] Ensembl ENSMUSP00000108469

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	494 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Catalytic activity	ATP + a protein = ADP + a phosphoprotein. SAAS SAAS003527
Sequence similarities	Contains 1 protein kinase domain. SAAS SAAS003527
Caution	The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSMUSP00000108469

Ontologies

Keywords
Ligand	ATP-binding SAAS SAAS003527 Nucleotide-binding
Molecular function	Kinase Serine/threonine-protein kinase SAAS SAAS003527 Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	MAPK cascade Inferred from electronic annotation. Source: GOC
Cellular_component	mitochondrion Inferred from direct assay PubMed 17724133. Source: MGI plasma membrane Inferred from direct assay PubMed 17724133. Source: MGI
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW MAP kinase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	E9QN59 [UniParc]. Last modified April 5, 2011. Version 1. Checksum: 0B07B6C2E5630B41	FASTA	494	55,714
	10 20 30 40 50 60 MGDTGVSGAP MKEMAQVMRI AEVTEDGRVF MSLHFLYYCS EPTLDVKIAF CQGFDKHVDV 70 80 90 100 110 120 SSIAKHYNMS KSKVDNQFYS VEVGDSTFTV LKRYQNLKPI GSGAQGIVCA AYDAVLDRNV 130 140 150 160 170 180 AIKKLSRPFQ NQTHAKRAYR ELVLMKCVNH KNIISLLNVF TPQKTLEEFQ DVYLVMELMD 190 200 210 220 230 240 ANLCQVIQME LDHERMSYLL YQMLCGIKHL HSAGIIHRDL KPSNIVVKSD CTLKILDFGL 250 260 270 280 290 300 ARTAGTSFMM TPYVVTRYYR APEVILGMGY KENVDIWSVG CIMGEMVRHK ILFPGRDYID 310 320 330 340 350 360 QWNKVIEQLG TPCPEFMKKL QPTVRNYVEN RPKYAGLTFP KLFPDSLFPA DSEHNKLKAS 370 380 390 400 410 420 QARDLLSKML VIDPAKRISV DDALQHPYIN VWYDPAEVEA PPPQIYDKQL DEREHTIEEW 430 440 450 460 470 480 KELIYKEVMN SEEKTKNGVV KGQPSPSGAA VNSSESLPPS SSVNDISSMS TDQTLASDTD 490 SSLEASAGPL GCCR

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Lineage-specific biology revealed by a finished genome assembly of the mouse." Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. , Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P. PLoS Biol. 7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: C57BL/6J Ensembl ENSMUSP00000108469.
[2]	Ensembl Submitted (MAY-2011) to UniProtKB Cited for: IDENTIFICATION. Strain: C57BL/6J Ensembl ENSMUSP00000108469.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC123664 Genomic DNA. No translation available. AC125252 Genomic DNA. No translation available. AC137121 Genomic DNA. No translation available. AC160244 Genomic DNA. No translation available.
IPI	IPI00623629.
3D structure databases
ProteinModelPortal	E9QN59.
SMR	E9QN59. Positions 41-430.
ModBase	Search...
Proteomic databases
PRIDE	E9QN59.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSMUST00000112848; ENSMUSP00000108469; ENSMUSG00000046709.
Organism-specific databases
MGI	MGI:1346863. Mapk10.
Phylogenomic databases
GeneTree	ENSGT00550000074271.
OMA	KEVMNFE.
Gene expression databases
ArrayExpress	E9QN59.
Bgee	E9QN59.
Family and domain databases
InterPro	IPR011009. Kinase-like_dom. IPR003527. MAP_kinase_CS. IPR008351. MAPK_JNK. IPR000719. Prot_kinase_cat_dom. IPR002290. Ser/Thr_dual-sp_kinase_dom. IPR008271. Ser/Thr_kinase_AS. [Graphical view]
Pfam	PF00069. Pkinase. 1 hit. [Graphical view]
PRINTS	PR01772. JNKMAPKINASE.
SMART	SM00220. S_TKc. 1 hit. [Graphical view]
SUPFAM	SSF56112. Kinase_like. 1 hit.
PROSITE	PS01351. MAPK. 1 hit. PS50011. PROTEIN_KINASE_DOM. 1 hit. PS00108. PROTEIN_KINASE_ST. 1 hit. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	MAPK10. mouse.
NextBio	35556055.
SOURCE	Search...

Entry information

Entry name

E9QN59_MOUSE

Accession

Primary (citable) accession number: E9QN59

Entry history

Integrated into UniProtKB/TrEMBL:	April 5, 2011
Last sequence update:	April 5, 2011
Last modified:	May 1, 2013
This is version 15 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)